Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yuanzhang, Zhou"'
Autor:
Yang Liu, Ting Liu, Yuanzhang Zhou, Wenjie Li, Min Wang, Nanshan Song, Wenbin Zhang, Jingwei Jiang, Shengtao Yuan, Jianhua Ding, Gang Hu, Ming Lu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 2, Pp 662-677 (2023)
Alanine–serine–cysteine transporter 2 (ASCT2) is reported to participate in the progression of tumors and metabolic diseases. It is also considered to play a crucial role in the glutamate-glutamine shuttle of neuroglial network. However, it remai
Externí odkaz:
https://doaj.org/article/1401357c85f546649511a5744180d615
Autor:
Yang Liu, Nanshan Song, Hang Yao, Siyuan Jiang, Yueping Wang, Ying Zheng, Yuanzhang Zhou, Jianhua Ding, Gang Hu, Ming Lu
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Major depressive disorder (MDD) is a prevalent and devastating psychiatric illness. Unfortunately, the current therapeutic practice, generally depending on the serotonergic system for drug treatment is unsatisfactory and shows int
Externí odkaz:
https://doaj.org/article/55a35af0ffc947ebb73efd322adade43
Autor:
Zheng Zhou, Yaokun Dong, Na Li, Mengyue Niu, Shisheng Wang, Yuanzhang Zhou, Zhaolin Sun, Peng Chu, Zeyao Tang
Publikováno v:
Cell Biology International. 46:1801-1813
Oleanolic acid (OA) and its derivatives show potent anticancer function. Pancreatic cancer (PC) is the fourth core motive of cancer-related deaths worldwide. Epidermal growth factor receptor (EGFR) has been implicated in PC and has been validated as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66db0430eb593b7711e034b39a82e94
https://doi.org/10.1002/cbin.11866
https://doi.org/10.1002/cbin.11866
Autor:
Elena, Montauti, Samuel E, Weinberg, Peng, Chu, Shuvam, Chaudhuri, Nikita L, Mani, Radhika, Iyer, Yuanzhang, Zhou, Yusi, Zhang, Changhong, Liu, Chen, Xin, Shana, Gregory, Juncheng, Wei, Yana, Zhang, Wantao, Chen, Zhaolin, Sun, Ming, Yan, Deyu, Fang
Publikováno v:
Science advances. 8(47)
The tumor microenvironment (TME) enhances regulatory T (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32b9e112037c1a69eef1a010d4df618e
https://pubmed.ncbi.nlm.nih.gov/36427305
https://pubmed.ncbi.nlm.nih.gov/36427305
Publikováno v:
Molecular Neurobiology. 58:1303-1311
Recent researches showed that nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3) inflammasome inhibition exerted dopaminergic neuroprotection in cellular or animal models of Parkinson's disease (PD). NLRP3 inflammasome has been propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64912e1b5bbe195cc57fb19bfc856107
https://doi.org/10.1007/s12035-020-02198-5
https://doi.org/10.1007/s12035-020-02198-5
Autor:
Jian-Hua Ding, Zhaoma Shu, Ming Lu, Xi-Yang Sun, Yiming Sun, Yaqi Bian, Gang Hu, Xiao-Dong Shu, Yuanzhang Zhou
Publikováno v:
Cell Death and Disease, Vol 10, Iss 8, Pp 1-16 (2019)
Cell Death & Disease
Cell Death & Disease
Although multiple hypotheses had been proposed to clarify the causes of depression, the accurate pathogenesis and effective treatment of depression still need to be solved. Pathological change of astrocytes has been recognized to play a pivotal role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4352deb9ef3d0dabc135a2a279300123
http://link.springer.com/article/10.1038/s41419-019-1813-9
http://link.springer.com/article/10.1038/s41419-019-1813-9
Autor:
Ran Yan, Liming Wang, Li Lv, Yan Hu, Yuanzhang Zhou, Ruimin Sun, Jihong Yao, Ning Zhang, Zhecheng Wang, Junyi Chu, Yan Zhao, Musen Lin, Wen Shan
Publikováno v:
Pharmacological research. 168
Alcohol-associated liver disease (ALD) is a liver system disease caused by alcohol abuse, and it involves complex processes ranging from steatosis to fibrosis, cirrhosis and hepatocellular carcinoma. Steatosis and inflammation are the main phenomena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7427dd8cf6f5d0c7b0f47bde3c9e6ee8
https://pubmed.ncbi.nlm.nih.gov/33826947
https://pubmed.ncbi.nlm.nih.gov/33826947
Publikováno v:
Molecular neurobiology. 58(4)
Recent researches showed that nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3) inflammasome inhibition exerted dopaminergic neuroprotection in cellular or animal models of Parkinson's disease (PD). NLRP3 inflammasome has been propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7c24666e4d5e49997a40c5d04a8462b
https://pubmed.ncbi.nlm.nih.gov/33169332
https://pubmed.ncbi.nlm.nih.gov/33169332
Autor:
Gang Hu, Mengdi Liu, Cong Wang, Ming Lu, Fangfang Zhao, Jian-Hua Ding, Meng Mei, Yuanzhang Zhou
Publikováno v:
Neuropharmacology. 160
Emerging evidence has demonstrated that the integrity and the function of blood-brain barrier (BBB) are gradually impaired in the processes of aging and nervous system disorders, including neurodegenerative diseases (e.g. Parkinson's disease, PD). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74878b8d84eda5b71bd2979afbfc3cc
https://pubmed.ncbi.nlm.nih.gov/31494143
https://pubmed.ncbi.nlm.nih.gov/31494143
Autor:
Jiaqian Han, Wei Li, Yuanzhang Zhou, Pengwu Zheng, Wufu Zhu, Tu Yuanbiao, Zhou Lan, Caolin Wang, Shan Xu
Publikováno v:
Bioorganicmedicinal chemistry. 25(12)
Two series of quinazoline derivatives bearing aryl semicarbazone scaffolds (9a-o and 10a-o) were designed, synthesized and evaluated for the IC50 values against four cancer cell lines (A549, HepG2, MCF-7 and PC-3). The selected compound 9o was furthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fae94a09fb155eb5d9562dba71be37
https://pubmed.ncbi.nlm.nih.gov/28428040
https://pubmed.ncbi.nlm.nih.gov/28428040