Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yuanxue, Huang"'
Autor:
Wenhan Deng, Alexandra Clipson, Hongxiang Liu, Yuanxue Huang, Rachel Dobson, Ming Wang, Peter Johnson, Ming-Qing Du
Publikováno v:
Translational Oncology, Vol 11, Iss 5, Pp 1147-1154 (2018)
Several newly developed drugs including JQ1 (BET inhibitor), ABT199 (BCL2 inhibitor), and bortezomib (proteasome inhibitor) may offer novel therapeutic strategies for aggressive diffuse large B-cell lymphoma (DLBCL). We tested these drugs together wi
Externí odkaz:
https://doaj.org/article/79c99316987d42e7a4a5bd19dd109841
Autor:
Wenyan Zhang, Lívia Rásó-Barnett, Zifen Gao, Yuanxue Huang, Ayoma D. Attygalle, Ming Wang, Zi Chen, Luis Miguel Pino Campos, Shaowei Zhang, George A Follows, Margaret Ashton-Key, Joe Sneath Thompson, Lorant Farkas, John W Grant, Hongxiang Liu, Alexandra Clipson, Ming-Qing Du, Hesham EI‐Daly, Hani Bibawi, Shih-Sung Chuang, Weiping Liu, Fangtian Wu, Penny Wright, Wen-Qing Yao
Publikováno v:
The Journal of Pathology
Angioimmunoblastic T‐cell lymphoma (AITL) is a neoplastic proliferation of T follicular helper cells with clinical and histological presentations suggesting a role of antigenic drive in its development. Genetically, it is characterized by a stepwis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ebec7f9827c283c27d2242a106a8bb
https://doi.org/10.1002/path.5376
https://doi.org/10.1002/path.5376
Autor:
Yingwen Bi, Naiyan Zeng, Estelle Chanudet, Yuanxue Huang, Rifat A. Hamoudi, Hongxiang Liu, Gehong Dong, A. James Watkins, Steven C. Ley, Lifen Zou, Rongjia Chen, Xiongzeng Zhu, Ming-Qing Du
Publikováno v:
Haematologica, Vol 97, Iss 6 (2012)
Recent studies showed A20 inactivation by deletion, mutation and promoter methylation in ocular adnexal mucosa-associated lymphoid tissue lymphoma. However, the incidences of A20 abnormalities and their clinical impact remain for the most part unknow
Externí odkaz:
https://doaj.org/article/8ffa92c762454c96b682622c51a9b771
Autor:
Qingguo Yan, Yuanxue Huang, A. James Watkins, Sylvia Kocialkowski, Naiyan Zeng, Rifat A. Hamoudi, Peter G. Isaacson, Laurence de Leval, Andrew Wotherspoon, Ming-Qing Du
Publikováno v:
Haematologica, Vol 97, Iss 4 (2012)
The genetics and pathogenesis of splenic marginal zone lymphoma are poorly understood. The lymphoma lacks chromosome translocation, and approximately 30% of cases are featured by 7q deletion, but the gene targeted by the deletion is unknown. A recent
Externí odkaz:
https://doaj.org/article/d006489dd1364bb6b9e845f7ba5efacb
Autor:
A James Watkins, Rifat A Hamoudi, Naiyan Zeng, Qingguo Yan, Yuanxue Huang, Hongxiang Liu, Jianzhong Zhang, Esteban Braggio, Rafael Fonseca, Laurence de Leval, Peter G Isaacson, Andrew Wotherspoon, Ellen D McPhail, Ahmet Dogan, Ming-Qing Du
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44997 (2012)
Splenic marginal zone lymphoma (SMZL) is an indolent B-cell lymphoproliferative disorder characterised by 7q32 deletion, but the target genes of this deletion remain unknown. In order to elucidate the genetic target of this deletion, we performed an
Externí odkaz:
https://doaj.org/article/e1d4ae1c07664ed4a79db9763d506bf1
Autor:
Olivier Giger, Anthony J. Bench, Ming-Qing Du, Lívia Rásó-Barnett, Yuanxue Huang, Michael A. Scott, Anna L. Paterson, Hesham Eldaly, Thomas Roberts, Hani Bibawi, Hongxiang Liu, Baljinder K Matharu, Elizabeth J. Soilleux
Publikováno v:
British journal of haematology. 185(2)
Identification of clonal IGH, IGK and IGL gene rearrangements offers diagnostic adjunct in suspected B-cell neoplasms. However, many centres omit IGL analysis as its value is uncertain. A review of 567 cases with IGH, IGK and IGL rearrangement assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685292d05cc2d5211efe082b35e4a01b
https://pubmed.ncbi.nlm.nih.gov/30681735
https://pubmed.ncbi.nlm.nih.gov/30681735
Autor:
Alexandra Clipson, Rachel Dobson, Peter Johnson, Ming-Qing Du, Ming Wang, Wenhan Deng, Yuanxue Huang, Hongxiang Liu
Publikováno v:
Translational Oncology, Vol 11, Iss 5, Pp 1147-1154 (2018)
Translational Oncology
Translational Oncology
Several newly developed drugs including JQ1 (BET inhibitor), ABT199 (BCL2 inhibitor), and bortezomib (proteasome inhibitor) may offer novel therapeutic strategies for aggressive diffuse large B-cell lymphoma (DLBCL). We tested these drugs together wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090ef5102df09203d49c1c6a563a194d
https://eprints.soton.ac.uk/422730/
https://eprints.soton.ac.uk/422730/
Autor:
Simon Crouch, Penny Wright, Jenny Buxton, Nicholas Francis Grigoropoulos, Ming-Qing Du, Bridget S. Wilkins, Yuanxue Huang, Andrew Jack, A. James Watkins, Michael J. Neat, Paul Fields, Lisa Worrillow, Sharon Barrans, Peter Johnson, Sylvia Kocialkowski, Hongxiang Liu, Alexandra Clipson, Eve Roman, Hesham EI‐Daly, John R. Goodlad, George A Follows, John W Grant, Ming Wang, Naiyan Zeng
Publikováno v:
The Journal of Pathology: Clinical Research. 1:125-133
A proportion of MYC translocation positive diffuse large B-cell lymphomas (DLBCL) harbour a BCL2 and/or BCL6 translocation, known as double-hit DLBCL, and are clinically aggressive. It is unknown whether there are other genetic abnormalities that coo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27b9777ee0826cc1e44a266941a0d9ba
https://doi.org/10.1002/cjp2.10
https://doi.org/10.1002/cjp2.10
Autor:
Annalise, Katz-Summercorn, Shubha, Anand, Sophie, Ingledew, Yuanxue, Huang, Thomas, Roberts, Nuria, Galeano-Dalmau, Maria, O'Donovan, Hongxiang, Liu, Rebecca C, Fitzgerald
Publikováno v:
The Journal of Pathology: Clinical Research
The early detection and endoscopic treatment of patients with the dysplastic stage of Barrett's oesophagus is a key to preventing progression to oesophageal adenocarcinoma. However, endoscopic surveillance protocols are hampered by the invasiveness o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::287e34046e9217fc2eb5d557c2dc9051
https://pubmed.ncbi.nlm.nih.gov/29085666
https://pubmed.ncbi.nlm.nih.gov/29085666
Autor:
Ming Wang, David R. Westhead, Matthew A. Care, Jon Laye, Gina M. Doody, Ming Du, Reuben Tooze, Andrew Jack, S. Barrans, Mario Cocco, Nicholas A. Barnes, Yuanxue Huang
Publikováno v:
Nucleic Acids Research
Interferon regulatory factor 4 (IRF4) is central to the transcriptional network of activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL), an aggressive lymphoma subgroup defined by gene expression profiling. Since cofactor association modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3dad1dfc1174b45709fe14b6c5d180d
https://doi.org/10.1093/nar/gku451
https://doi.org/10.1093/nar/gku451