Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yuanxing, Zhi"'
Autor:
Xiaoyan Wu, Xin Yi, Boxin Zhao, Yuanxing Zhi, Ziwei Xu, Ying Cao, Xiong Cao, Jianxin Pang, Ken Kin Lam Yung, Shiqing Zhang, Shuwen Liu, Pingzheng Zhou
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 107016- (2023)
The NLRP3 inflammasome is a supramolecular complex that is linked to sterile and pathogen-dependent inflammation, and its excessive activation underlies many diseases. Ion flux disturbance and cell volume regulation are both reported to mediate NLRP3
Externí odkaz:
https://doaj.org/article/d8d493bd9e1d4acd8d32e06aaa0de23a
Autor:
Xin Zhang, Xiulin Lin, Hui Luo, Yuanxing Zhi, Xin Yi, Xiaoyan Wu, Wendi Duan, Ying Cao, Jianxin Pang, Shuwen Liu, Pingzheng Zhou
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106112- (2022)
Emerging data have demonstrated the critical roles of potassium efflux in the innate immune system. However, the role of potassium efflux in TLR3/4 activation and type I interferon (IFN) responses are not well elucidated. In the present study, we fou
Externí odkaz:
https://doaj.org/article/9006914cad0e4935be71a309d68cb262
Autor:
Xin, Zhang, Xiulin, Lin, Hui, Luo, Yuanxing, Zhi, Xin, Yi, Xiaoyan, Wu, Wendi, Duan, Ying, Cao, Jianxin, Pang, Shuwen, Liu, Pingzheng, Zhou
Publikováno v:
Pharmacological research. 177
Emerging data have demonstrated the critical roles of potassium efflux in the innate immune system. However, the role of potassium efflux in TLR3/4 activation and type I interferon (IFN) responses are not well elucidated. In the present study, we fou
Autor:
Yuanxing, Zhi, Jin, Liu, Peihua, Kuang, Xin, Zhang, Ziwei, Xu, Yanshan, Chen, Xiuling, Lin, Xiaoyan, Wu, Pingzheng, Zhou, Jianjun, Chen
Publikováno v:
Biochemical Pharmacology. 199:114988
The enzyme cyclic GMP-AMP synthase (cGAS) senses cytosolic DNA and catalyzes the formation of 2'3'-cyclic-GMP-AMP (cGAMP), which in turn triggers interferon (IFN) production. Inappropriate activation of cGAS and production of cGAMP have been linked t
Autor:
Xin Zhang, Xiuling Lin, Hui Luo, Yuanxing Zhi, Xin Yi, Xiaoyan Wu, Wendi Duan, Ying Cao, Jianxin Pang, Shuwen Liu, Pingzheng Zhou
Publikováno v:
Pharmacological Research. 178:106192