Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yuanxiao Tang"'
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111452- (2024)
Summary: As an essential regulator of higher-order chromatin structures, CCCTC-binding factor (CTCF) is a highly conserved protein with a central DNA-binding domain of 11 tandem zinc fingers (ZFs), which are flanked by amino (N-) and carboxy (C-) ter
Externí odkaz:
https://doaj.org/article/33561798f80043cbb43272bdc35cc028
Autor:
Huihua Ding, Yubo Wang, Ying Shen, Yuting Qin, Zang X, Yuming Guo, Honglin Xu, Chao Yao, Ning Xu, Yunting Zhang, Zhou M, Jianyang Ma, Yin Z, Yuanxiao Tang, Nan Shen, Weirauch Mt, Kenneth M. Kaufman, Xiaomei Zhu, Zhizhong Ye, Tian Zhou, Guojun Hou, Wangling Yang, Leah C. Kottyan, Bahram Namjou, John B. Harley
Dysregulated transcription factors represent a major class of drug targets that mediate the abnormal expression of many critical genes involved in SLE and other autoimmune diseases. Although strong evidence suggests that natural human genetic variati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9182cc8d0e89e54224aa67ef4f4d51df
https://doi.org/10.1101/2021.06.11.448156
https://doi.org/10.1101/2021.06.11.448156
Publikováno v:
Nucleic Acids Research
Repressor element-1 silencing transcription factor (REST) or neuron-restrictive silencer factor (NRSF) is a zinc-finger (ZF) containing transcriptional repressor that recognizes thousands of neuron-restrictive silencer elements (NRSEs) in mammalian g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e6fd1be425e51903176dedf358536d
https://doi.org/10.1101/2021.03.06.434230
https://doi.org/10.1101/2021.03.06.434230
Autor:
Yuanxiao Tang, Ya Guo, Quan Xu, Yanan Zhai, Zhilian Jia, Qiang Wu, Yonghu Wu, Zhifeng Chen, Jia Shou, Li Jinhuan
Publikováno v:
Journal of Molecular Cell Biology
The human genome contains millions of DNA regulatory elements and a large number of gene clusters, most of which have not been tested experimentally. The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated nuclease 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd456311e9aeb2a506aeb751e3067f73
https://doi.org/10.1093/jmcb/mjv016
https://doi.org/10.1093/jmcb/mjv016
Publikováno v:
Nucleic Acids Research; 5/7/2021, Vol. 49 Issue 8, p4506-4521, 16p, 4 Diagrams, 3 Graphs
Publikováno v:
Molecular and Cellular Biology. 34:3895-3910
The globus pallidus (GP) is a central component of basal ganglia whose malfunctions cause a variety of neuropsychiatric disorders as well as cognitive impairments in neurodegenerative diseases such as Parkinson's disease. Here we report that the prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06f810199aaa5375a49f9397fa186ad
https://doi.org/10.1128/mcb.00760-14
https://doi.org/10.1128/mcb.00760-14
Autor:
Jinhuan Li, JiaShou, YaGuo, Yuanxiao Tang, Yonghu Wu, Zhilian Jia, Yanan Zhai, Zhifeng Chen, Quan Xu, Qiang Wu
Publikováno v:
Journal of Molecular Cell Biology; Aug2015, Vol. 7 Issue 4, p284-289, 15p
Publikováno v:
Molecular & Cellular Biology; 10/15/2014, Vol. 34 Issue 20, p3895-3910, 16p
Autor:
Zhilian Jia, Qiang Wu, Bing Ren, Li Jinhuan, Yanan Zhai, Quan Xu, David U. Gorkin, Michael Q. Zhang, Ya Guo, Yonghu Wu, Tom Maniatis, Wei Li, Adrian R. Krainer, Haiyang Wu, Inkyung Jung, Daniele Canzio, Yichao Lu, Yuanxiao Tang, Jia Shou
Publikováno v:
Cell, vol 162, iss 4
SummaryCTCF and the associated cohesin complex play a central role in insulator function and higher-order chromatin organization of mammalian genomes. Recent studies identified a correlation between the orientation of CTCF-binding sites (CBSs) and ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7cae776863c464fe56731e1b4e5215