Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Yuanqing, Yan"'
High wall shear stress-dependent podosome formation in a novel murine model of intracranial aneurysm
Publikováno v:
Frontiers in Stroke, Vol 3 (2024)
High wall shear stress (HWSS) contributes to intracranial aneurysm (IA) development. However, the underlying molecular mechanisms remain unclear, in part due to the lack of robust animal models that develop IAs in a HWSS-dependent manner. The current
Externí odkaz:
https://doaj.org/article/16a5b449d5394c38aa2094a503b7a917
Autor:
Cheng-Kai Shiau, Lina Lu, Rachel Kieser, Kazutaka Fukumura, Timothy Pan, Hsiao-Yun Lin, Jie Yang, Eric L. Tong, GaHyun Lee, Yuanqing Yan, Jason T. Huse, Ruli Gao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Single-cell nanopore sequencing of full-length mRNAs transforms single-cell multi-omics studies. However, challenges include high sequencing errors and dependence on short-reads and/or barcode whitelists. To address these, we develop scNanoG
Externí odkaz:
https://doaj.org/article/43beb0e6e87041e6ac17042241fa61ab
Autor:
Lina Lu, Jennifer Rui Wang, Ying C. Henderson, Shanshan Bai, Jie Yang, Min Hu, Cheng-Kai Shiau, Timothy Pan, Yuanqing Yan, Tuan M. Tran, Jianzhuo Li, Rachel Kieser, Xiao Zhao, Jiping Wang, Roza Nurieva, Michelle D. Williams, Maria E. Cabanillas, Ramona Dadu, Naifa Lamki Busaidy, Mark Zafereo, Nicholas Navin, Stephen Y. Lai, Ruli Gao
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 11 (2023)
The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated thyroid cancer (DTC); however, the complex intratumor transformation process is poorly understood. We investigated an anaplastic transformation model by disse
Externí odkaz:
https://doaj.org/article/0d8eae2e1a504a25ac0667fae8df590b
Autor:
Balveen Kaur, Guangsheng Pei, Zhongming Zhao, Jianhua Yu, Bangxing Hong, Upasana Sahu, Matthew P Mullarkey, Evan Hong, Yuanqing Yan, Yoshihiro Otani, Yeshavanth Banasavadi-Siddegowda, Huihui Fan, Michael A Caligiuri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Mammalian cells have developed multiple intracellular mechanisms to defend against viral infections. These include RNA-activated protein kinase (PKR), cyclic GMP-AMP synthase and stimulation of interferon genes (cGAS-STING) and toll-like r
Externí odkaz:
https://doaj.org/article/7f0511cf9c4748f3863cef617f7c1245
Autor:
Wenbin Yang, Emily Jeong Cerier, Félix L. Núñez-Santana, Qiang Wu, Yuanqing Yan, Chitaru Kurihara, Xianpeng Liu, Anjana Yeldandi, Nigar Khurram, Diego Avella-Patino, Haiying Sun, G.R. Scott Budinger, Daniel Kreisel, Thalachallour Mohanakumar, Emilia Lecuona, Ankit Bharat
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
Preexisting lung-restricted autoantibodies (LRAs) are associated with a higher incidence of primary graft dysfunction (PGD), although it remains unclear whether LRAs can drive its pathogenesis. In syngeneic murine left lung transplant recipients, pre
Externí odkaz:
https://doaj.org/article/6acb2674719446cabb799ad8228631c6
Autor:
Feng Wang, Kiyomi Morita, Courtney D. DiNardo, Ken Furudate, Tomoyuki Tanaka, Yuanqing Yan, Keyur P. Patel, Kyle J. MacBeth, Bin Wu, Guowen Liu, Mark Frattini, Jairo A. Matthews, Latasha D. Little, Curtis Gumbs, Xingzhi Song, Jianhua Zhang, Erika J. Thompson, Tapan M. Kadia, Guillermo Garcia-Manero, Elias Jabbour, Farhad Ravandi, Kapil N. Bhalla, Marina Konopleva, Hagop M. Kantarjian, P. Andrew Futreal, Koichi Takahashi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The regulation of resistance to IDH inhibitors in acute myeloid leukaemia is not completely understood. Here the authors reveal with integrative multi-omics analyses that stemness features are major drivers of primary resistance, while high-risk muta
Externí odkaz:
https://doaj.org/article/af530f137f2d430f8c1dd47dd38789db
Autor:
Aradhana M. Venkatesan, Eniola Mudairu-Dawodu, Cihan Duran, R. Jason Stafford, Yuanqing Yan, Wei Wei, Vikas Kundra
Publikováno v:
Cancer Imaging, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The utility of multiparametric MRI (mpMRI) in detecting suspected local recurrence post radical prostatectomy (RP) may be associated with PSA and Gleason grade. The purpose of the study was to evaluate the likelihood of detecting
Externí odkaz:
https://doaj.org/article/e4bf6bc869c846fabf939a72a306be37
Autor:
Kiyomi Morita, Feng Wang, Katharina Jahn, Tianyuan Hu, Tomoyuki Tanaka, Yuya Sasaki, Jack Kuipers, Sanam Loghavi, Sa A. Wang, Yuanqing Yan, Ken Furudate, Jairo Matthews, Latasha Little, Curtis Gumbs, Jianhua Zhang, Xingzhi Song, Erika Thompson, Keyur P. Patel, Carlos E. Bueso-Ramos, Courtney D. DiNardo, Farhad Ravandi, Elias Jabbour, Michael Andreeff, Jorge Cortes, Kapil Bhalla, Guillermo Garcia-Manero, Hagop Kantarjian, Marina Konopleva, Daisuke Nakada, Nicholas Navin, Niko Beerenwinkel, P. Andrew Futreal, Koichi Takahashi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Understanding the evolutionary trajectory of cancer samples may enable understanding resistance to treatment. Here, the authors used single cell sequencing of a cohort of acute myeloid leukemia tumours and identify features of linear and branching ev
Externí odkaz:
https://doaj.org/article/c334158e79f74f09bd8df84c3b7562c1
Autor:
Bangxing Hong, Kamaldeen Muili, Chelsea Bolyard, Luke Russell, Tae Jin Lee, Yeshavanth Banasavadi-Siddegowda, Ji Young Yoo, Yuanqing Yan, Leomar Y. Ballester, Kurt H. Bockhorst, Balveen Kaur
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss , Pp 93-102 (2019)
HMGB1 is a ubiquitously expressed intracellular protein that binds DNA and transcription factors and regulates chromosomal structure and function. Under conditions of cell death or stress, it is actively or passively released by cells into the extrac
Externí odkaz:
https://doaj.org/article/185c5a6fa40c4a3782fdededeedc9563
Autor:
Barlas Benkli, Sun Young Kim, Nobuya Koike, Chorong Han, Celia K. Tran, Emma Silva, Yuanqing Yan, Kazuhiro Yagita, Zheng Chen, Seung-Hee Yoo, Mark J. Burish
Publikováno v:
Neurology. 100:e2224-e2236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9a0b4953226b4f8f43cf16877c47c5e
https://doi.org/10.1212/wnl.0000000000207240
https://doi.org/10.1212/wnl.0000000000207240