Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Yuanqiang wang"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveAs a novel drug formulation, antibody drug conjugates (ADCs) are widely used in various types of cancer. However, clinically, there is a lack of attention to the CVD produced by them, as well as a lack of research on the real-world situation
Externí odkaz:
https://doaj.org/article/c5937ae11eb64635b8653b3fbef0905c
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 620 (2024)
In situ depot gel is a type of polymeric long-acting injectable (pLAI) drug delivery system; compared to microsphere technology, its preparation process is simpler and more conducive to industrialization. To ensure the chemical stability of peptide A
Externí odkaz:
https://doaj.org/article/8daec77f00d2413cb5c15d7fdd986c83
Autor:
Jin Cheng, Yixuan Hao, Qin Shi, Guanyu Hou, Yanan Wang, Yong Wang, Wen Xiao, Joseph Othman, Junnan Qi, Yuanqiang Wang, Yan Chen, Guanghua Yu
Publikováno v:
Molecules, Vol 28, Iss 3, p 937 (2023)
The transmission and infectivity of COVID-19 have caused a pandemic that has lasted for several years. This is due to the constantly changing variants and subvariants that have evolved rapidly from SARS-CoV-2. To discover drugs with therapeutic poten
Externí odkaz:
https://doaj.org/article/a5316ec98b3c47509fc3b55906698291
Autor:
Mengjun Zhang, Yuanqiang Wang, Xiangqian Li, Gang Meng, Xiaoling Chen, Lina Wang, Zhihua Lin, Li Wang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Autoreactive CD8+ T cells play an indispensable key role in the destruction of pancreatic islet β-cells and the initiation of type 1 diabetes (T1D). Insulin is an essential β-cell autoantigen in T1D. An HLA-A*0201-restricted epitope of insulin A ch
Externí odkaz:
https://doaj.org/article/92f23dea53084ec1a93b4c747af46943
Autor:
Yan Chen, Zhiwei Feng, Mingzhe Shen, Weiwei Lin, Yuanqiang Wang, Siyi Wang, Caifeng Li, Shengfeng Wang, Maozi Chen, Weiguang Shan, Xiang-Qun Xie
Publikováno v:
ACS Omega, Vol 5, Iss 5, Pp 2428-2439 (2020)
Externí odkaz:
https://doaj.org/article/78bee7c9bf1443ecb09a58bb5113f960
Publikováno v:
Molecules, Vol 20, Iss 1, Pp 1014-1030 (2015)
The mitochondrial cytochrome P450 enzymes inhibitor steroid 11β-hydroxylase (CYP11B1) can decrease the production of cortisol. Therefore, these inhibitors have an effect in the treatment of Cushing’s syndrome. A pharmacophore model generated by Ge
Externí odkaz:
https://doaj.org/article/532cdf436d124f90a174e0df0ce888a0
Autor:
Yuanqiang Wang, Haiqiong Guo, Zhiwei Feng, Siyi Wang, Yuxuan Wang, Qingxiu He, Guangping Li, Weiwei Lin, Xiang-Qun Xie, Zhihua Lin
Publikováno v:
Molecules, Vol 24, Iss 20, p 3784 (2019)
The blockade of the programmed cell death protein 1/programmed cell death ligand 1 (PD-1/PD-L1) pathway plays a critical role in cancer immunotherapy by reducing the immune escape. Five monoclonal antibodies that antagonized PD-1/PD-L1 interaction ha
Externí odkaz:
https://doaj.org/article/e644c8f46a2a42da8067e0edd35783d5
Publikováno v:
Molecules, Vol 24, Iss 18, p 3390 (2019)
Studies have indicated that Na+-d-glucose co-transporter (SGLT) inhibitors had anti-proliferative activity by attenuating the uptake of glucose in several tumor cell lines. In this study, the molecular docking showed that, trilobatin, one of the dihy
Externí odkaz:
https://doaj.org/article/f6289363df664c9cb4ca29b45f49cff2
Publikováno v:
Molecules, Vol 17, Iss 2, Pp 2015-2029 (2012)
Human mitotic kinesin Eg5 plays an essential role in mitoses and is an interesting drug target against cancer. To find the correlation between Eg5 and its inhibitors, structure-based 3D-quantitative structure–activity relationship (QSAR) studies we
Externí odkaz:
https://doaj.org/article/26da66bc686848f481d0aa579ac4ecae
Publikováno v:
International Journal of Antennas and Propagation, Vol 2015 (2015)
A printed dual-element antenna array for LTE MIMO mobile phone applications is presented in this paper. The two array elements are symmetrically placed with the same dimensions, and each of the them consists of a novel driven strip and a wandering sh
Externí odkaz:
https://doaj.org/article/aef2437e358a4da3a481d0f7b1511fad