Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yuanming Cheng"'
Autor:
Yuanming Cheng, Hanzhi Luo, Franco Izzo, Brian F. Pickering, Diu Nguyen, Robert Myers, Alexandra Schurer, Saroj Gourkanti, Jens C. Brüning, Ly P. Vu, Samie R. Jaffrey, Dan A. Landau, Michael G. Kharas
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1703-1716.e6 (2019)
Summary: Stem cells balance cellular fates through asymmetric and symmetric divisions in order to self-renew or to generate downstream progenitors. Symmetric commitment divisions in stem cells are required for rapid regeneration during tissue damage
Externí odkaz:
https://doaj.org/article/d0575c334f4841de919b97361dfd2bba
Autor:
Ning Wei, Yuanming Cheng, Zhijia Wang, Yuguo Liu, Chunling Luo, Lina Liu, Linlin Chen, Zhiqin Xie, Yun Lu, Ying Feng
Publikováno v:
Cell Reports, Vol 13, Iss 8, Pp 1647-1657 (2015)
Alternative splicing is a major mechanism of controlling gene expression and protein diversity in higher eukaryotes. We report that the splicing factor SRSF10 functions during striated muscle development, myoblast differentiation, and glucose product
Externí odkaz:
https://doaj.org/article/fb5628686ff5487cb40003115c2947f0
Publikováno v:
Genomics Data, Vol 2, Iss C, Pp 20-23 (2014)
Splicing factor SRSF10 is known to function as a sequence-specific splicing activator that is capable of regulating alternative splicing both in vitro and in vivo. We recently used an RNA-seq approach coupled with bioinformatics analysis to identify
Externí odkaz:
https://doaj.org/article/046cf2166fe44afd94077385ed64ca8f
Autor:
Maurizio Scaltriti, Pedram Razavi, Jorge S. Reis-Filho, Sarat Chandarlapaty, Fabrice Andre, Alicia Tran-Dien, Alexandra Jacquet, Marta Jimenez, Eneda Toska, Komal Jhaveri, Alison Zhao, Yuanming Cheng, Pau Castel, Erik Ladewig, Pier Selenica, Xuan Qu, Carmen Chan, Flavia Michelini, Fan Wu, Guotai Xu, Yanyan Cai
Supplemental Tables 1-4. Table S1. Sequences of sgRNAs and oligonucleotides; Table S2. GSEA pathway enrichment analysis of enriched and dropout genes in MCF7 and T47D cells; Table S3. The top 2.5% (3745) enriched sgRNAs of whole-genome CRISPR/Cas9 sg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f1f4d741990626626ce17d344076d3
https://doi.org/10.1158/0008-5472.22429978
https://doi.org/10.1158/0008-5472.22429978
Autor:
Ying Feng, Wenwu Wu, Zhiqin Xie, Ning Wei, Lina Liu, Linlin Chen, Yuguo Liu, Yuanming Cheng, Chunling Luo
Aberrant RNA splicing is recognized to contribute to cancer pathogenesis, but the underlying mechanisms remain mainly obscure. Here, we report that the splicing factor SRSF2 is upregulated frequently in human hepatocellular carcinoma (HCC), where thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eda6196436706d7abbfd30b3a2ad2b9
https://doi.org/10.1158/0008-5472.c.6509318
https://doi.org/10.1158/0008-5472.c.6509318
Autor:
Ying Feng, Wenwu Wu, Zhiqin Xie, Ning Wei, Lina Liu, Linlin Chen, Yuguo Liu, Yuanming Cheng, Chunling Luo
Supplementary Fig S1. SRSF2 increases colony-forming efficiencies of hepatocarcinoma cells. Supplementary Fig S2. Exogenous expression of SRSF2 in KD cells restores WT splicing patterns of SRSF2-targeted transcripts. Supplementary Fig S3. Knockdown o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f669221849382f1ab02623b97e1aebb
https://doi.org/10.1158/0008-5472.22415552.v1
https://doi.org/10.1158/0008-5472.22415552.v1
Autor:
Yuanming Cheng
Publikováno v:
Materials; Volume 15; Issue 6; Pages: 2268
Five-axis working machines are applied in the high-precision machining of complex convex surfaces. Therefore, this study integrated a horizontal parallel three-axis motion platform and a three-axis machine tools to create a reconfigurable precision f
Autor:
Eneda Toska, Emiliano Cocco, Jane Park, Jorge S. Reis-Filho, Ross L. Levine, Pier Selenica, Jordan E. Otto, Maurizio Scaltriti, Fan Wu, Clayton K. Collings, Lorenzo Ferrando, Komal Jhaveri, Carmen Chan, Erik Ladewig, Huiyong Zhao, José Baselga, Yanyan Cai, Sagar Chhangawala, Mirna Sallaku, Cristian Serna-Tamayo, Pedram Razavi, Richard Koche, Andrew R. D’Avino, Christina S. Leslie, Guotai Xu, Alison Zhao, Arnaud Da Cruz Paula, Yuanming Cheng, Cigall Kadoch, Xuan Qu, Matthew Witkin
Publikováno v:
Nat Genet
Mutations in ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, are the most common alterations of the SWI/SNF complex in estrogen-receptor-positive (ER(+)) breast cancer. We identify that ARID1A inactivating mutations are present at a hi
Publikováno v:
Cell Stem Cell
In this issue of Cell Stem Cell, Shen et al. (2020) and Wang et al. (2020) independently identify the essential function of m(6)A demethylase ALKBH5 in maintaining myeloid leukemia stem cells. These studies expand the regulators of the epitranscripto
Publikováno v:
Cancer Discovery. 9:25-33
Hematopoietic development and differentiation are highly regulated processes, and recent studies focusing on m6A mRNA methylation have uncovered how this mark controls cell fate in both normal and malignant hematopoietic states. In this review, we fo