Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yuanjie Wen"'
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 4, Pp 519-529 (2021)
The liver is an important organ for drugs disposition, and thus how to accurately evaluate hepatic clearance is essential for proper drug dosing. However, there are many limitations in drug dosage adjustment based on liver function and pharmacogenomi
Externí odkaz:
https://doaj.org/article/e1f5c4b656284e2cab704dca8b8f3e43
Publikováno v:
Asian Journal of Pharmaceutical Sciences
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 4, Pp 519-529 (2021)
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 4, Pp 519-529 (2021)
The liver is an important organ for drugs disposition, and thus how to accurately evaluate hepatic clearance is essential for proper drug dosing. However, there are many limitations in drug dosage adjustment based on liver function and pharmacogenomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9cdd6bd2a86c23d08e0f2de6da1152
https://doi.org/10.1016/j.ajps.2021.03.002
https://doi.org/10.1016/j.ajps.2021.03.002
Publikováno v:
Toxicology. 476
Anti-tuberculosis drugs-induced liver injury may be associated with the hepatic farnesoid X receptor (FXR). However, the relationship between isoniazid, rifampicin, pyrazinamide and ethambutol (HRZE) coadministration-induced liver injury and FXR has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a375e2b554e47ec9857f4a96685e2c47
https://pubmed.ncbi.nlm.nih.gov/35835356
https://pubmed.ncbi.nlm.nih.gov/35835356
Publikováno v:
European journal of pharmacology. 885
Cholestasis causes the intrahepatic accumulation of bile acids leading to hepatobiliary injury. Recently obeticholic acid, a farnesoid X receptor (FXR) agonist, was FDA-approved to treat cholestatic liver diseases, providing a new therapeutic strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647b43c4570a325a896106c7b424c25f
https://pubmed.ncbi.nlm.nih.gov/32841642
https://pubmed.ncbi.nlm.nih.gov/32841642
Publikováno v:
Toxicology and applied pharmacology. 402
Isoniazid (INH)-induced liver injury may be associated with inhibition of the liver farnesoid X receptor (FXR). However, the relationship between FXR and INH-induced liver injury remained unclear. The present study was performed to clarify the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe241d2721abed32815ab89e1fd9511b
https://pubmed.ncbi.nlm.nih.gov/32673658
https://pubmed.ncbi.nlm.nih.gov/32673658
Publikováno v:
Asian Journal of Pharmaceutical Sciences; Jul2021, Vol. 16 Issue 4, p519-529, 11p
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307393 (2024)
Global warming has led to the expansion of arid lands and more frequent droughts, which are the largest cause of global food production losses. In our previous study, we developed TaPYLox wheat overexpressing the plant hormone abscisic acid (ABA) rec
Externí odkaz:
https://doaj.org/article/aa4f7eaa838e4895b04a1fc91f27e370