Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yuanhua Cai"'
Autor:
Yuan Chen, Xianglei Chen, Lili Pan, Yuanmao Huang, Yuanhua Cai, Jinggang Li, Yang Li, Shaoyuan Wang
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background DHX15 is one of the RNA helicase family members involving in several biological processes. Studies have reported that overexpression of DHX15 is related to cancer progression. However, the role of DHX15 in Burkitt lymphoma (BL) an
Externí odkaz:
https://doaj.org/article/a88d74874e7d42e1acd79227d4b891b8
Autor:
Yuanhua Cai, Jocelyn A. Schroeder, Weiqing Jing, Cody Gurski, Calvin B. Williams, Shaoyuan Wang, Bonnie N. Dittel, Qizhen Shi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system with no cure yet. Here, we report genetic engineering of hematopoietic stem cells (HSCs) to express myelin oligodendrocyte glycoprotein (MOG), specific
Externí odkaz:
https://doaj.org/article/ec6a2fddd5f34326a50e945eeb517ef7
Autor:
Weiqing Jing, Juan Chen, Yuanhua Cai, Yingyu Chen, Jocelyn A. Schroeder, Bryon D. Johnson, Weiguo Cui, Qizhen Shi
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 3099-3110 (2019)
Abstract: The development of neutralizing anti-FVIII antibodies (inhibitors) is a major complication of FVIII protein replacement therapy in patients with hemophilia A (HA). Although multiple lines of evidence indicate that the immune response agains
Externí odkaz:
https://doaj.org/article/538a91862d0c4f2abde43edc1239876f
Autor:
Chunyan Gao, Jocelyn A. Schroeder, Feng Xue, Weiqing Jing, Yuanhua Cai, Amelia Scheck, Saravanan Subramaniam, Sridhar Rao, Hartmut Weiler, Agnieszka Czechowicz, Qizhen Shi
Publikováno v:
Blood Advances, Vol 3, Iss 18, Pp 2700-2711 (2019)
Gene therapy offers the potential to cure hemophilia A (HA). We have shown that hematopoietic stem cell (HSC)–based platelet-specific factor VIII (FVIII) (2bF8) gene therapy can produce therapeutic protein and induce antigen-specific immune toleran
Externí odkaz:
https://doaj.org/article/83420e9f07c946c78fd2d34f6a0da735
Autor:
Fuquan Tu, Lili Pan, Wenwei Wu, Yuanhua Cai, Jinggang Li, Xuechun Wang, Xiaolin Lai, Zhixiang Chen, Luya Ye, Shaoyuan Wang
Publikováno v:
Journal of Leukocyte Biology; Nov2023, Vol. 114 Issue 5, p443-458, 16p
Autor:
Yuanhua Cai, Qizhen Shi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Platelets are small anucleated blood components primarily described as playing a fundamental role in hemostasis and thrombosis. Over the last decades, increasing evidence has demonstrated the role of platelets in modulating inflammatory reactions and
Externí odkaz:
https://doaj.org/article/c33ba0ba3b0a4dfcaab841bfed2a687f
Autor:
Jiucun Wang, Xue-Chun Wang, Tao P. Zhong, Yuanhua Cai, Shao-Yuan Wang, Yang Li, Xianglei Chen, Daqing Jin, Feng Qian, Lili Pan, Jing Wang, Qiao Liu
Publikováno v:
Cancer Science
Gene alterations are recognized as important events in acute myeloid leukemia (AML) progression. Studies on hematopoiesis of altered genes contribute to a better understanding on their roles in AML progression. Our previous work reported a DEAH box h
Publikováno v:
Tumor Biology, Vol 39 (2017)
Xianyou county of Fujian province, located on the southeast coastal of China, has higher gastric cancer mortality. Chronic inflammation plays an important role in the occurrence of gastric cancer, in which the nuclear factor-κB signaling pathway of
Externí odkaz:
https://doaj.org/article/7b0517e38f4749f2bad46a361accfe33
Autor:
Yingyu Chen, Jocelyn A. Schroeder, Qizhen Shi, Yuanhua Cai, Paul E. Monahan, Juan Chen, Hongyin Yu, Jeremy G Mattson
Publikováno v:
Blood Adv
Gene therapy may lead to a cure for hemophilia B (HB) if it is successful. Data from clinical trials using adeno-associated virus (AAV)–mediated liver-targeted FIX gene therapy are very encouraging. However, this protocol can be applied only to adu
Autor:
Jinpeng Yao, Yuanhua Cai, Zhixiang Chen, Xuechun Wang, Xiaolin Lai, Lili Pan, Yang Li, Shaoyuan Wang
Publikováno v:
Genomics. 115:110578