Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yuanhong Bi"'
Publikováno v:
Electronic Research Archive, Vol 32, Iss 1, Pp 293-316 (2024)
In this paper, the stability and bifurcation of a two–dimensional p53 gene regulatory network without and with time delay are taken into account by rigorous theoretical analyses and numerical simulations. In the absence of time delay, the existence
Externí odkaz:
https://doaj.org/article/53c972da28e848aabe558a5347336bc2
Publikováno v:
Electronic Research Archive, Vol 30, Iss 3, Pp 850-873 (2022)
In this paper, based on a p53 gene regulatory network regulated by Programmed Cell Death 5(PDCD5), a time delay in transcription and translation of Mdm2 gene expression is introduced into the network, the effects of the time delay on oscillation dyna
Externí odkaz:
https://doaj.org/article/6774e512a7b5420b974131543c23310b
Publikováno v:
IET Systems Biology, Vol 15, Iss 3, Pp 101-109 (2021)
Abstract The dynamics of cortical neuronal activity plays important roles in controlling body movement and is regulated by connection weights between neurons in a cortex–basal ganglia–thalamus (BGCT) loop. Beta‐band oscillation of cortical acti
Externí odkaz:
https://doaj.org/article/921639ceeb874b06a8d2e724852b7e6c
Publikováno v:
Complexity, Vol 2020 (2020)
Exploring the behaviors of beta oscillations in the basal ganglia is helpful to understand the mechanism of Parkinson’s disease. Studies have shown that the external and internal segments (GPe, GPi) of the globus pallidus receive different intensit
Externí odkaz:
https://doaj.org/article/bd158a0352a0467ea9c7909e6b17493d
Publikováno v:
IET Systems Biology, Vol 15, Iss 3, Pp 101-109 (2021)
The dynamics of cortical neuronal activity plays important roles in controlling body movement and is regulated by connection weights between neurons in a cortex–basal ganglia–thalamus (BGCT) loop. Beta‐band oscillation of cortical activity is c
Publikováno v:
Nonlinear Dynamics. 103:2903-2916
MicroRNAs are able to modulate gene expression at the posttranscriptional level and play an essential role in various biological processes. In this paper, we establish a general model of an miRNA-mediated gene regulatory network motif with extracellu
Publikováno v:
Chaos, Solitons & Fractals. 166:112885
Publikováno v:
International Journal of Bifurcation and Chaos. 31
p53 dynamics plays an important role in determining cell arrest or apoptosis upon DNA damage response. In this paper, based on a p53 gene regulatory network composed of its core regulator ATM, Mdm2 and Wip1, the effect of multiple time delays in tran
Publikováno v:
Communications in Nonlinear Science and Numerical Simulation. 102:105918
In this paper, considering blood as an incompressible Newtonian fluid, we explore the propagation of blood flow. Based on the Navier–Stokes equations and the continuity equation, the vorticity equation is deduced. Then, using the multi-scale analys
Publikováno v:
Theoretical Biology & Medical Modelling
Theoretical Biology and Medical Modelling, Vol 16, Iss 1, Pp 1-9 (2019)
Theoretical Biology and Medical Modelling, Vol 16, Iss 1, Pp 1-9 (2019)
Background Autophagy and apoptosis are two important physiological processes that determine cell survival or death in response to different stress signals. The regulatory mechanisms of these two processes share B-cell lymphoma-2 family proteins and A