Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yuangang Su"'
Publikováno v:
ACS Omega, Vol 9, Iss 31, Pp 33574-33593 (2024)
Externí odkaz:
https://doaj.org/article/477e3108834a4861a219556596e02a25
Autor:
Zhijuan Liu, Yijie Gao, Xiaoliang Feng, Yuangang Su, Haoyu Lian, Jinmin Zhao, Jiake Xu, Qian Liu, Fangming Song
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116933- (2024)
Reactive oxidative species (ROS) generation triggers pyroptosis and induces development of inflammatory osteolysis. Hecogenin (HG) has anti-inflammatory and antioxidative property, but its effects on inflammatory osteolysis remains unclear. In our st
Externí odkaz:
https://doaj.org/article/d8e2b1a54f1e48c5af79f69bda47ecad
Autor:
Kai Gan, Haoyu Lian, Tao Yang, Jian Huang, Junchun Chen, Yuangang Su, Jinmin Zhao, Jiake Xu, Qian Liu
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract The key target for treating inflammatory osteolysis is osteoclasts. In an inflammatory environment, osteoclast differentiation increases, and bone resorption is enhanced. Periplogenin (Ppg) is a traditional Chinese medicine. It has anti-infl
Externí odkaz:
https://doaj.org/article/b884611b500a471a85a0456188af4ee7
Autor:
Tao Yang, Weiwei Chen, Kai Gan, Chaofeng Wang, Xiaoxiao Xie, Yuangang Su, Haoyu Lian, Jiake Xu, Jinmin Zhao, Qian Liu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Activated osteoclasts cause excessive bone resorption, and disrupt bone homeostasis, leading to osteoporosis. The extracellular signal-regulated kinase (ERK) signaling is the classical pathway related to osteoclast differentiation
Externí odkaz:
https://doaj.org/article/529da04999ca4eec8f36a80200b95eab
Autor:
Hailong Teng, Biao Yang, Yuangang Su, Junchun Chen, Lei Cui, Ran Sun, Jinmin Zhao, Qian Liu, An Qin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115605- (2023)
The second most common cancer among men is prostate cancer, which is also the fifth leading reason for male cancer deaths worldwide. Bone metastases are the main factor affecting the prognosis of prostate cancer. Consequently, antitumor and anti-pros
Externí odkaz:
https://doaj.org/article/dd760589e5794acb9ea1f7aab0d3f23b
Autor:
Minglian Xu, Dezhi Song, Xiaoxiao Xie, Yiwu Qin, Jian Huang, Chaofeng Wang, Junchun Chen, Yuangang Su, Jiake Xu, Jinmin Zhao, Qian Liu
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107760- (2023)
Summary: Osteoporosis is a prevalent systemic metabolic disease in modern society, in which patients often suffer from bone loss due to over-activation of osteoclasts. Currently, amelioration of bone loss through modulation of osteoclast activity is
Externí odkaz:
https://doaj.org/article/7cd94c79399b4e77b17e625973dab16e
Autor:
Hui Wang, Dezhi Song, Linhua Wei, Linke Huang, Donglei Wei, Yuangang Su, Jiamin Liang, Haoyu Lian, Jinmin Zhao, Qian Liu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114508- (2023)
Heterotopic ossification (HO) denotes the presence of mature bone tissue in soft tissues or around joints. Inflammation is a key driver of traumatic HO, and macrophages play an important role in this process. Ethyl caffeate (ECF), a critical active c
Externí odkaz:
https://doaj.org/article/819befb4f3f64da3829f0e525c8f90fe
Autor:
Yiwu Qin, Dezhi Song, Shijie Liao, Junchun Chen, Minglian Xu, Yuangang Su, Haoyu Lian, Hui Peng, Linhua Wei, Kai Chen, Jiake Xu, Jinmin Zhao, Qian Liu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114347- (2023)
The formation of osteoclasts and their hyperactive bone resorption are related to the aggregation of intracellular reactive oxygen species (ROS). Flavonoids, derived from plant active ingredients, can alleviate the symptoms of osteoporosis (OP). Isos
Externí odkaz:
https://doaj.org/article/840c67229095470185303b8ed4f80e43
Autor:
Yang Xu, Dezhi Song, Yuangang Su, Junchun Chen, Liwei Wu, Haoyu Lian, Na Hai, Jing li, Jie Jiang, Jinmin Zhao, Jiake Xu, Qian Liu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114101- (2023)
4-Methylcatechol (4-MC) is an agonist of various neurotrophic factors, which can upregulate the expression of Heme oxygenase 1 (HO-1) protein by activating nuclear factor erythroid 2-related factor 2 (Nrf2), thereby inhibiting oxidative stress-induce
Externí odkaz:
https://doaj.org/article/6b7012807097475191d60e860cbb457f
Autor:
Biao Yang, Yuangang Su, Shuai Han, Runfeng Chen, Ran Sun, Kewei Rong, Feng Long, Hailong Teng, Jinmin Zhao, Qian Liu, An Qin
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Osteoclasts undergo active metabolic reprogramming to acquire the energy needed during differentiation and bone resorption. Compared with immature osteoclasts, mature osteoclasts comprise higher levels of electron transport chain enzymes and more met
Externí odkaz:
https://doaj.org/article/f8fae486ad484a8db0b376ce8080da67