Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Yuanfu Xu"'
Autor:
Ruibo Chen, Tianran Cheng, Sisi Xie, Xiaoting Sun, Mingjia Chen, Shumin Zhao, Qingyan Ruan, Xiaolei Ni, Mei Rao, Xinyi Quan, Kaiwen Chen, Shiyue Zhang, Tao Cheng, Yuanfu Xu, Yuguo Chen, Yunlong Yang, Yihai Cao
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) are common hematological malignancies in adults. Despite considerable research advances, the development of standard therapies, supportive care, and prognosis for the majori
Externí odkaz:
https://doaj.org/article/a1eb68033e5d480892816695b5cd8e45
Autor:
Kayoko Hosaka, Chenchen Wang, Shiyue Zhang, Xue Lv, Takahiro Seki, Yin Zhang, Xu Jing, Jieyu Wu, Qiqiao Du, Xingkang He, Yulong Fan, Xuan Li, Makoto Kondo, Masahito Yoshihara, Hong Qian, Lihong Shi, Ping Zhu, Yuanfu Xu, Yunlong Yang, Tao Cheng, Yihai Cao
Publikováno v:
Cancer Communications, Vol 43, Iss 6, Pp 637-660 (2023)
Abstract Background Tumors possess incessant growth features, and expansion of their masses demands sufficient oxygen supply by red blood cells (RBCs). In adult mammals, the bone marrow (BM) is the main organ regulating hematopoiesis with dedicated m
Externí odkaz:
https://doaj.org/article/8df481223bdb46a19afced0251c70f02
Autor:
Yigeng Cao, Jiali Wang, Shan Jiang, Mengnan Lyu, Fei Zhao, Jia Liu, Mingyang Wang, Xiaolei Pei, Weihua Zhai, Xiaoming Feng, Sizhou Feng, Mingzhe Han, Yuanfu Xu, Erlie Jiang
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract Objectives Ruxolitinib, a Janus kinase (JAK) 1/2 inhibitor, demonstrates efficacy for treating steroid‐resistant acute graft‐versus‐host disease (SR‐aGVHD) following allogeneic stem cell transplantation (allo‐HSCT). Myeloid‐deriv
Externí odkaz:
https://doaj.org/article/be8510b24b7b49af83a76c6c101bbf94
Autor:
Kayoko Hosaka, Yunlong Yang, Takahiro Seki, Qiqiao Du, Xu Jing, Xingkang He, Jieyu Wu, Yin Zhang, Hiromasa Morikawa, Masaki Nakamura, Martin Scherzer, Xiaoting Sun, Yuanfu Xu, Tao Cheng, Xuri Li, Xialin Liu, Qi Li, Yizhi Liu, An Hong, Yuguo Chen, Yihai Cao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Anti-VEGF therapy has many limitations that might be resolved by using combination treatment approaches. Here, the authors demonstrate that the dual-targeting of VEGF and PDGF is required for targeting resistant FGF2+ tumors which depend on the recru
Externí odkaz:
https://doaj.org/article/67e5eca4e69c483cb274470b002be274
Autor:
Lu Chen, Xianfu Yi, Piao Guo, Hua Guo, Ziye Chen, Chunyu Hou, Lisha Qi, Yongrong Wang, Chengwen Li, Peng Liu, Yucun Liu, Yuanfu Xu, Ning Zhang
Publikováno v:
Cancer Biology & Medicine, Vol 17, Iss 1, Pp 142-153 (2020)
Objective: Epithelial cancers often originate from progenitor cells, while the origin of hepatocellular carcinoma (HCC) is still controversial. HCC, one of the deadliest cancers, is closely linked with liver injuries and chronic inflammation, which t
Externí odkaz:
https://doaj.org/article/fc87a8df64514067aedcb8d711ba6032
Autor:
Li Ma, Chunhua She, Qian Shi, Qiang Yin, Xinxin Ji, Yongrong Wang, Yulong Fan, Xinyao Kong, Peng Li, Zengfeng Sun, Xiaohui Zhang, Zhen Zhang, Jian Wang, Tong Wang, Yuanfu Xu, Wenliang Li
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 3, Pp 606-617 (2019)
Objective More than half of human glioblastomas show EGFR gene amplification and mutation, but EGFR inhibitors have not been effective in treating EGFR-positive glioblastoma patients. The mechanism behind this type of primary resistance is not well u
Externí odkaz:
https://doaj.org/article/a9c185ed459846a4b49fe9abf3676197
Autor:
Mengge Wang, Hongtao Wang, Yuqi Wen, Xiaoyuan Chen, Xin Liu, Jie Gao, Pei Su, Yuanfu Xu, Wen Zhou, Lihong Shi, Jiaxi Zhou
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-13 (2018)
Abstract Background Despite considerable progress in the development of methods for hematopoietic differentiation, efficient generation of transplantable hematopoietic stem cells (HSCs) and other genuine functional blood cells from human embryonic st
Externí odkaz:
https://doaj.org/article/b5213ca3e6f5453a86b8465ee2e9d710
Autor:
Xiaoyu Zhang, Kutay Karatepe, Direkrit Chiewchengchol, Haiyan Zhu, Rongxia Guo, Peng Liu, Hongbo Yu, Qian Ren, Xiao Luo, Tao Cheng, Fengxia Ma, Yuanfu Xu, Mingzhe Han, Hongbo R. Luo
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Pathogen-initiated chronic inflammation or autoimmune diseases accelerate proliferation and promote differentiation of hematopoietic stem cells (HSCs) but simultaneously reduce reconstitution capacity. Nevertheless, the effect of acute infection and
Externí odkaz:
https://doaj.org/article/a3cde2e710584b1e980e46c79dc60146
Autor:
Kutay Karatepe, Haiyan Zhu, Xiaoyu Zhang, Rongxia Guo, Hiroto Kambara, Fabien Loison, Peng Liu, Hongbo Yu, Qian Ren, Xiao Luo, John Manis, Tao Cheng, Fengxia Ma, Yuanfu Xu, Hongbo R. Luo
Publikováno v:
Stem Cell Reports, Vol 11, Iss 5, Pp 1092-1105 (2018)
Summary: Hematopoietic stem and progenitor cells (HSPCs) undergo self-renewal and differentiation to guarantee a constant supply of short-lived blood cells. Both intrinsic and extrinsic factors determine HSPC fate, but the underlying mechanisms remai
Externí odkaz:
https://doaj.org/article/3d9d3603a5284d5f802879ab3bf06d5c
Autor:
Leisheng Zhang, Hongtao Wang, Cuicui Liu, Qingqing Wu, Pei Su, Dan Wu, Jiaojiao Guo, Wen Zhou, Yuanfu Xu, Lihong Shi, Jiaxi Zhou
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 497-513 (2018)
Summary: The gap in knowledge of the molecular mechanisms underlying differentiation of human pluripotent stem cells (hPSCs) into the mesenchymal cell lineages hinders the application of hPSCs for cell-based therapy. In this study, we identified a cr
Externí odkaz:
https://doaj.org/article/743d956fb9094592915f952633905479