Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Yuancheng Chen"'
Autor:
Yuran Cao, Jingjing Wang, Xingyu Tang, Yan Tian, Jicheng Yu, Hong Liang, Jufang Wu, Yuancheng Chen, Guoying Cao, Jing Zhang
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0296940 (2024)
Mesalazine is a well-established treatment for ulcerative colitis by oral or topical administration. However, the pharmacokinetic (PK) and safety profiles of mesalazine administered by an enema has not been clarified in Chinese population. We conduct
Externí odkaz:
https://doaj.org/article/96169cf126d44edfab53b53e77677b41
Autor:
Na Wang, Yuancheng Chen, Xingyi Qu, Xingchen Bian, Jiali Hu, Xiaogang Xu, Li Xiao, Yang Liu, Jing Zhang
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Mycoplasma pneumoniae is the causative agent of respiratory infections in children and adults. Macrolide still plays a significant role in treating infections by M. pneumoniae. However, macrolide-resistant M. pneumoniae (MRMP) was encountere
Externí odkaz:
https://doaj.org/article/4b8a19b5fa3a4e408971e7f13bfb9279
Publikováno v:
Antibiotics, Vol 13, Iss 6, p 497 (2024)
This study conducted a quantitative meta-analysis to investigate the association of vancomycin indicators, particularly area under the curve over 24 h (AUC24) and trough concentrations (Ctrough), and their relationship with both nephrotoxicity and ef
Externí odkaz:
https://doaj.org/article/ae3e8412dc084614a69eaa8ec83a867f
Autor:
Shanshan Li, Xiaojie Wu, Nanyang Li, Guoying Cao, Jingjing Wang, Yuancheng Chen, Size Li, Jinjie He, Jufang Wu, Haijing Yang, Ke Lin, Chao Qiu, Angela Liu, He Zhou, Francisco Adrian, Liang Schweizer, Wenhong Zhang, Jingwen Gu, Jing Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objective: The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) still protracts worldwide. HFB30132A is an anti- SARS-CoV-2 monoclonal antibody purposely engineered for an extended
Externí odkaz:
https://doaj.org/article/0e5267ec43d046bda3c93c9e5f568cc1
Autor:
Yuancheng Chen, Xiaojie Wu, Chengyuan Tsai, Liwen Chang, Jicheng Yu, Guoying Cao, Beining Guo, Yaoguo Shi, Demei Zhu, Fupin Hu, Jinyi Yuan, Yang Liu, Xu Zhao, Yingyuan Zhang, Jufang Wu, Jing Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Nemonoxacin is an innovative quinolone antibiotic for treatment of community-acquired pneumonia (CAP). As more data are available from clinical studies, it is necessary to perform an integrative pharmacokinetic/pharmacodynamic (PK/PD) a
Externí odkaz:
https://doaj.org/article/102adff3a6dd4b28a447fde2e61315e0
Autor:
Ming Zhao, Yuancheng Chen, Dong Yang, Cheng Lyu, Xingchen Bian, Xin Li, Weiyi Qiu, Zhiwei Huang, Zijian Hu, Jing Zhang
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 12, Pp 1466-1478 (2021)
Abstract Pharmacometrics is an emerging science that interprets drug, disease, and trial information in a mathematical fashion to inform and facilitate efficient drug development and/or regulatory decisions. Pharmacometrics study is increasingly adop
Externí odkaz:
https://doaj.org/article/eb56930a6bfd4339a10ecd4798829480
Autor:
Huanhuan Qi, Xin Li, Yuancheng Chen, Xueyuan Zhang, Meng Yang, Cancan Li, Hao Feng, Jing Zhang, Chunlei Li
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 23, Iss , Pp 113-119 (2020)
Objectives: We reported the pharmacokinetic/pharmacodynamic (PK/PD) targets of a biosimilar generic product of amphotericin B colloidal dispersion (G-ABCD) againstCandida albicans (MIC 1–2 μg/mL) in a rat model of invasive candidiasis (IC) to faci
Externí odkaz:
https://doaj.org/article/1f3973cd55b4440f990a624dad203ba2
Autor:
Haijing Yang, Zhiwei Huang, Yuancheng Chen, Yusong Zhu, Guoying Cao, Jingjing Wang, Yan Guo, Jicheng Yu, Jufang Wu, Lichuan Liu, Jun Deng, Jing Liu, Harald Reinhart, Jing Zhang, Xiaojie Wu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: Omadacycline is a new type of aminomethylcycline antibiotic, having a broad antibacterial spectrum. But the pharmacokinetic characteristics and safety profile of the Chinese population remain unknown. It is also unclear whether the US-appr
Externí odkaz:
https://doaj.org/article/835c36f73093449cb301f7112048faf0
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 22, Iss , Pp 608-612 (2020)
Objective: G-ABCD is a biosimilar product of amphotericin B colloidal dispersion (ABCD). This study was designed to systematically examine the plasma pharmacokinetics (PK) and tissue distribution of G-ABCD in rats, using amphotericin B deoxycholate (
Externí odkaz:
https://doaj.org/article/8ff2dfb818e04365ad6a4ffa25c906b7
Autor:
Xingchen Bian, Xiaofen Liu, Fupin Hu, Meiqing Feng, Yuancheng Chen, Phillip J. Bergen, Jian Li, Xin Li, Yan Guo, Jing Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
The latest PK/PD findings have demonstrated negligible efficacy of intravenous polymyxins against pulmonary infections. We investigated pharmacokinetic/pharmacodynamic (PK/PD)-based breakpoints of polymyxin B for bloodstream infections and the ration
Externí odkaz:
https://doaj.org/article/921ac7e372c04582bc4c8cd7eacae4cb