Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yuanbiao Tu"'
Autor:
Linxiao Wang, Xiaoling Huang, Shidi Xu, Yufeng An, Xinya Lv, Wufu Zhu, Shan Xu, Yuanbiao Tu, Shuhui Chen, Qiaoli Lv, Pengwu Zheng
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-14 (2024)
Abstract Background Facing the significant challenge of overcoming drug resistance in cancer treatment, particularly resistance caused by mutations in epidermal growth factor receptor (EGFR), the aim of our study was to identify potent EGFR inhibitor
Externí odkaz:
https://doaj.org/article/dc1948ba5a58471095b3f8bb7ecc4a8e
Autor:
Yuanbiao Tu, Caolin Wang, Zunhua Yang, Bingbing Zhao, Luogen Lai, Qi Yang, Pengwu Zheng, Wufu Zhu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 16, Iss , Pp 462-478 (2018)
Aimed at discovering effective EGFR inhibitors, six series of quinazoline derivatives bearing a semicarbazone moiety were designed, synthesized and evaluated in different cancer cell lines (A549, HepG2, MCF-7 and PC-3). Most of the selected compounds
Externí odkaz:
https://doaj.org/article/ee56ad5b4a9649ee836c8b9185c0f7e9
Publikováno v:
Analytical Chemistry. 95:7344-7353
Autor:
Kaili Qin, Suling Xin, Gang Li, Kuncheng Zhou, Rongbin Pan, Shuying Chen, Tianming Tao, Changsheng Li, Ji Tao, Ray P.S. Han, Yuanbiao Tu
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 239:112648
Autor:
Zhaolun Li, Yi Ma, Ji Tao, Yueqing Gu, Fang Wang, Zicun Liu, Zhihao Han, Yuanbiao Tu, Changsheng Li, Peifei Liu
Publikováno v:
ACS Sensors. 5:4072-4080
Hepatocellular carcinoma (HCC) is characterized by a high mortality and early diagnosis and treatment are critically needed. Ang II type 1 receptor (AT1R) has recently emerged as a potential molecular target for cancer diagnosis and intervention. Her
Publikováno v:
Biomaterials Science. 8:2682-2693
Pancreatic cancer has a high mortality rate and efforts towards diagnosis and therapy at an early stage are particularly appealing. Recently, a small peptide, BBN7-14, has attracted much attention for its specific binding ability to gastrin releasing
Autor:
Luogen Lai, Wanqing Zou, Yan Zhang, Yuanbiao Tu, Simeng Li, Tongxuan Xin, Tianyue Zhou, Shan Xu, Pengwu Zheng, Qingshan Pan, Wufu Zhu
Publikováno v:
Chemical Engineering Journal. 435:135084
Autor:
Fang Wang, Peifei Liu, Ji Tao, Zicun Liu, Zhaolun Li, Zhihao Han, Yueqing Gu, Yuanbiao Tu, Yi Ma
Publikováno v:
Biomaterials science. 8(23)
Colorectal cancer (CRC) is the third most common cancer worldwide, and the prognosis of CRC is better with an earlier diagnosis. The presence of the gastrin-releasing peptide receptor (GRPR) has been documented in very high numbers on colorectal canc
Publikováno v:
Biomaterials science. 8(21)
Aureins, natural active peptides extracted from skin secretions of Australian bell frogs, have become a research focus due to the antitumor effects caused by lysing cell membranes. However, clinical translation of Aureins is still limited by non-sele
Publikováno v:
Biomaterials. 235
Cancer starvation therapy based on catalytic chemistry of glucose oxidase (GOx) offers great potential for multimodal treatment, benefiting from both nutrition shutting-off and the oxidization product hydrogen peroxide (H2O2). Herein, further optimiz