Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yuan-Yuan Zhai"'
Autor:
Rejoice Thubelihle Ndebele, Qing Yao, Yan-Nan Shi, Yuan-Yuan Zhai, He-Lin Xu, Cui-Tao Lu, Ying-Zheng Zhao
Publikováno v:
BIO Integration, Vol 3, Iss 2, Pp 71-83 (2022)
Nanotechnology is associated with the development of particles in the nano-size range that can be used in a wide range of applications in the medical field. It has gained more importance in the pharmaceutical research field particularly in drug deliv
Externí odkaz:
https://doaj.org/article/e2aefc7aff5345efa54d1eb6b20f69c6
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 2, Pp 268-283 (2022)
Psoriasis is a common chronic immune-mediated skin disease characterized by hyperproliferation and aberrant differentiation of keratinocytes and massive infiltration of inflammatory immune cells. Recent studies showed that Signal Transducer and Activ
Externí odkaz:
https://doaj.org/article/1b3b524d5f294b6ebca396d93acee234
Autor:
Zhe Zhang, Xiang Kai Leng, Yuan Yuan Zhai, Xiao Zhang, Zhi Wei Sun, Jun Ying Xiao, Jun Feng Lu, Kun Liu, Bo Xia, Qi Gao, Miao Jia, Cheng Qi Xu, Yi Na Jiang, Xiao Gang Zhang, Kai Shan Tao, Jiang Wei Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Liver injury is a core pathological process in the majority of liver diseases, yet the genetic factors predisposing individuals to its initiation and progression remain poorly understood. Here we show that asialoglycoprotein receptor 1 (ASGR
Externí odkaz:
https://doaj.org/article/e9e4812692804d69afd203ccfd5ded3c
Autor:
Qing Yao, Yuan-Yuan Zhai, Rejoice Thubelihle Ndebele, He-Lin Xu, Cui-Tao Lu, Yannan Shi, Ying-Zheng Zhao
Publikováno v:
BIO Integration. 3:71-83
Nanotechnology is associated with the development of particles in the nano-size range that can be used in a wide range of applications in the medical field. It has gained more importance in the pharmaceutical research field particularly in drug deliv
Publikováno v:
Current Bioinformatics. 17:206-216
Background: Epithelial-Mesenchymal Transition (EMT) and its reverse Mesenchymal- Epithelial Transition (MET) are essential for tumor cells metastasis. However, the effect of epigenetic modifications on this transition is unclear. Objective: We aimed
Autor:
Qing Yao, Yuan-Yuan Zhai, Zhimin He, Qian Wang, Lining Sun, Tuyue Sun, Leyao Lv, Yingtao Li, Jiyong Yang, Donghui Lv, Ruijie Chen, Hailin Zhang, Xiang Luo, Longfa Kou
Publikováno v:
Asian Journal of Pharmaceutical Sciences. 18:100782
Autor:
Meng-Ting Lin, Ying-Zheng Zhao, Qing-Hua Lan, Yuan-Yuan Zhai, Longfa Kou, He-Lin Xu, Jian Xiao, Qing Yao
Publikováno v:
Molecular Pharmaceutics. 17:3857-3869
Disulfiram (DSF) is an FDA-approved anti-alcoholic drug that has recently proven to be effective in cancer treatment. However, the short half-life in the bloodstream and the metal ion-dependent antitumor activity significantly limited the further app
Autor:
Ying-Zheng Zhao, Zhi-Wei Huang, Qing Yao, Lan-Zi Luo, Yong-Hui Han, Yue Meng, Longfa Kou, Yuan-Yuan Zhai, Peng-Peng Xue, He-Lin Xu
Publikováno v:
ACS Applied Materials & Interfaces. 12:5462-5475
Islet transplantation has been considered the most promising therapeutic option with the potential to restore the physiological regulation of blood glucose concentrations in type 1 diabetes treatment. However, islets suffer from oxidative stress and
Autor:
Yan-Ling Sun, Yubo Fan, Jing Du, Xin-Bin Zhao, Lan Zhao, Yuan-Yuan Zhai, Xi-Qiao Feng, Yan Gong, Min Tan, Yun-Ping Chen
Publikováno v:
Advanced healthcare materials. 10(16)
Extracellular matrix (ECM) stiffness has profound effects on the regulation of cell functions. DNA methylation is an important epigenetic modification governing gene expression. However, the effects of ECM stiffness on DNA methylation remain elusive.
Autor:
Zhi-Wei Huang, Run-Jie Yu, Jiaoyuan Zhai, Qing Yao, Yuan-Yuan Zhai, Yannan Shi, Ying-Zheng Zhao, Longfa Kou, Jian Xiao, Chu-Chu Du
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 334
Acute kidney injury (AKI) is a common pathological process that is globally associated with a high morbidity and mortality rate. The underlying AKI mechanisms include over-produced reactive oxygen species (ROS), inflammatory cell infiltration, and hi