Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yuan-Xiang Shi"'
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33206- (2024)
Background: Egl-9 family hypoxia-inducible factor 3 (EGLN3) is involved in the regulation of tumor microenvironment and tumor progression. However, its biological function and clinical significance in various cancers remain unclear. Methods: RNA-seq,
Externí odkaz:
https://doaj.org/article/dabb31755c50473b95c157e80b64c590
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background More and more studies have demonstrated that potassium channel tetramerization domain-containing 5 (KCTD5) plays an important role in the development of cancer, but there is a lack of comprehensive research on the biological funct
Externí odkaz:
https://doaj.org/article/d91dd96233d24f9ead8cb31633038416
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract To obtain novel insights into the tumor biology and therapeutic targets of LUAD, we performed a comprehensive analysis of the KCTD family genes. The expression patterns and clinical significance of the KCTD family were identified through mul
Externí odkaz:
https://doaj.org/article/8593ccd322cd413cbc7436a6d5bd4dcb
Publikováno v:
Translational Oncology, Vol 31, Iss , Pp 101658- (2023)
Background: During mitosis and meiosis, centromere proteins (CENPs) play a key role in proper chromosome segregation. Abnormal expression of CENPs leads to chromosome instability, which is the main cause of tumorigenesis. Methods: To elucidate the fu
Externí odkaz:
https://doaj.org/article/7384c42a0ef14446a5480eb86053e62b
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Epigenetic alterations are strongly associated with the development of cancer. The aim of this study was to identify epigenetic pattern in squamous cell lung cancer (LUSC) on a genome-wide scale. Results Here we performed DNA meth
Externí odkaz:
https://doaj.org/article/cd231a4234424f7291ce26e75eb53ac4
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract This study aims to identify promising biomarkers for the early detection of lung cancer and evaluate the prognosis of lung cancer patients. Genome-wide mRNA expression data obtained from the Gene Expression Omnibus (GSE19188, GSE18842 and GS
Externí odkaz:
https://doaj.org/article/0f15c54d952b407e9ccc6da6024cb1a6
Akademický článek
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Autor:
Yuan-Xiang Shi
Publikováno v:
Oncology Letters
Lung cancer is a major public health problem worldwide, with a high associated incidence and mortality. In the present study, novel epigenetic signatures were identified through genome-wide DNA methylation microarrays. The results revealed that tripa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
This study aims to identify promising biomarkers for the early detection of lung cancer and evaluate the prognosis of lung cancer patients. Genome-wide mRNA expression data obtained from the Gene Expression Omnibus (GSE19188, GSE18842 and GSE40791),
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2019 (2019)
Journal of Oncology, Vol 2019 (2019)
Lung cancer is the leading cause of cancer-related mortality worldwide. Tumorigenesis involves a multistep process resulting from the interactions of genetic, epigenetic, and environmental factors. Genome-wide association studies and sequencing studi