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pro vyhledávání: '"Yuan-Tong Liu"'
Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
Autor:
Qi-Chao Yang, Shuo Wang, Yuan-Tong Liu, An Song, Zhi-Zhong Wu, Shu-Cheng Wan, Hui-Min Li, Zhi-Jun Sun
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106916- (2023)
Summary: Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been demonstrated to play a critical role in regulating cholesterol homeostasis and T cell antitumor immunity. However, the expression, function, and therapeutic value of PCSK9 in hea
Externí odkaz:
https://doaj.org/article/6c9538931e2b41bb8241871ed8a29bb0
Autor:
Jun-Jie Zhou, Xiao-Hong Li, Peng-Yu He, Fu-Yu Qi, Muhammad Wajid Ullah, Shu-Jin Li, Yuan-Tong Liu, Lin-Lin Bu, Guang Yang, Zhi-Jun Sun
Publikováno v:
Nano Research. 16:951-963
Publikováno v:
Cancer Letters. 558:216105
Publikováno v:
Molecular Carcinogenesis. 60:556-566
The epithelial-mesenchymal transition (EMT) is a pivotal step involved in cancer recurrence and metastasis. In addition, the activation of the EMT program can induce a cancer stem cell (CSC)-like phenotype and programmed death-ligand 1 (PD-L1) expres
Autor:
Zhi-Jun Sun, Yuan-Tong Liu
Publikováno v:
Theranostics
Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has greatly improved the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend on the infiltration of T cells capable of recognizing and killing tumor
Autor:
Yuan-Tong Liu, Zhi-Jun Sun
Publikováno v:
Theranostics; 2021, Vol. 11 Issue 11, p5365-5386, 22p