Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yuan-Ting Hsieh"'
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141088 (2015)
CPT-11 is an anticancer prodrug that is clinically used for the treatment of metastatic colorectal cancer. Hydrolysis of CPT-11 by human carboxylesterase 2 (CE2) generates SN-38, a topoisomerase I inhibitor that is the active anti-tumor agent. Expres
Externí odkaz:
https://doaj.org/article/36861091ab354b7a9596594001e60242
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118028 (2015)
CPT-11 is a camptothecin analog used for the clinical treatment of colorectal adenocarcinoma. CPT-11 is converted into the therapeutic anti-cancer agent SN-38 by liver enzymes and can be further metabolized to a non-toxic glucuronide SN-38G, resultin
Externí odkaz:
https://doaj.org/article/be23ae563e5c4341b7c364fcfca4b304
Autor:
Yuan-Ting Hsieh, 謝源庭
103
CPT-11, also known as Irinotecan, is a prodrug used for the first-line treatment of colorectal cancer. In humans, CPT-11 is hydrolyzed by human carboxylesterase 2 (hCE2) into SN-38. SN-38 is the active form of the drug that to serves as a DN
CPT-11, also known as Irinotecan, is a prodrug used for the first-line treatment of colorectal cancer. In humans, CPT-11 is hydrolyzed by human carboxylesterase 2 (hCE2) into SN-38. SN-38 is the active form of the drug that to serves as a DN
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/73025283200098435762
Autor:
Yuan-Ting Hsieh, 謝源庭
96
H. pylori is a common gastrointestinal bacterium that causes chronic inflammation for lifelong. Many factors were investigated to see their functions on immune suppression. However, these factors may not be strong enough to help every stain e
H. pylori is a common gastrointestinal bacterium that causes chronic inflammation for lifelong. Many factors were investigated to see their functions on immune suppression. However, these factors may not be strong enough to help every stain e
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/26225119436124699434
Publikováno v:
IEEE Transactions on Very Large Scale Integration (VLSI) Systems. 25:2803-2816
Reliability issues are more severe in multi/many-core systems because of the integration of more devices in advanced technology nodes. To achieve robust computing in nanoscale designs, many circuit-level and architecture-level redundancy techniques h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd585b8c90e704a9fce2ff57bd6df3a7
https://doi.org/10.1109/tvlsi.2017.2715803
https://doi.org/10.1109/tvlsi.2017.2715803
Publikováno v:
ICME
In this paper, we propose a novel algorithm of Generalized Joint Distribution Adaptation (G-JDA) for heterogeneous domain adaptation (HDA), which associates and recognizes cross-domain data observed in different feature spaces (and thus with differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d29be720aafd7e2f5521ae8795daa79
https://doi.org/10.1109/icme.2016.7552878
https://doi.org/10.1109/icme.2016.7552878
Autor:
Ching Yi Lin, Kuang-Wen Liao, Jaw-Town Lin, Yuan Ting Hsieh, Yi-Han Chiu, Ming-Shiang Wu, Ping-Ning Hsu, Po-Ren Hsueh
Publikováno v:
The Journal of Infectious Diseases. 196:1386-1393
BACKGROUND The cytokines induced by Helicobacter pylori, as well as the intricate balance of proinflammatory and anti-inflammatory cytokines, are relevant to the outcomes of H. pylori infection. Transforming growth factor (TGF)-beta and interleukin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f560c1e9f8c90b1afb9c3ede0cda44
https://doi.org/10.1086/522520
https://doi.org/10.1086/522520
Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141088 (2015)
PLoS ONE
PLoS ONE
CPT-11 is an anticancer prodrug that is clinically used for the treatment of metastatic colorectal cancer. Hydrolysis of CPT-11 by human carboxylesterase 2 (CE2) generates SN-38, a topoisomerase I inhibitor that is the active anti-tumor agent. Expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0b705f58f53b9c9dd35993e5667c95
http://europepmc.org/articles/PMC4624787?pdf=render
http://europepmc.org/articles/PMC4624787?pdf=render
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 2, p e0118028 (2015)
PLoS ONE, Vol 10, Iss 2, p e0118028 (2015)
CPT-11 is a camptothecin analog used for the clinical treatment of colorectal adenocarcinoma. CPT-11 is converted into the therapeutic anti-cancer agent SN-38 by liver enzymes and can be further metabolized to a non-toxic glucuronide SN-38G, resultin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5dc66de437ded0ba2067564cfac601
https://pubmed.ncbi.nlm.nih.gov/25688562
https://pubmed.ncbi.nlm.nih.gov/25688562
Autor:
Zeljko M. Prijovich, Tian-Lu Cheng, Cheng-Pao Chen, Steve R. Roffler, Qingzong Tseng, Wei-Cheng Lu, Yuan-Ting Hsieh, Yu-Lin Leu, Kai-Chuan Chen, Huai-Yao Chuang
Publikováno v:
Protein engineering, designselection : PEDS. 25(7)
We describe an adjustable membrane-tethered/soluble protein screening methodology termed ECSTASY (enzyme cleavable surface tethered all-purpose screening system) which combines the power of high-throughput fluorescence-activated cell sorting of membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff9b29dca37d23065b5a6c1ab6b35c8
https://pubmed.ncbi.nlm.nih.gov/22691701
https://pubmed.ncbi.nlm.nih.gov/22691701