Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Yuan-Ping Pang"'
Autor:
Yuan-Ping Pang
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-11 (2022)
Neocarcerand Octacid4 can assemble with small molecule guests at room temperature to produce irreversible noncovalent bimolecular complexes, but the nature of the self-assembly pathway remains poorly understood. Here, the author uses unrestricted, un
Externí odkaz:
https://doaj.org/article/dbb4a916dc034087aad0adc26eeb3a09
Autor:
Katherine G. McFerrin, Yuan-Ping Pang
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-12 (2021)
Molecular dynamics simulation can reveal conformational dynamics of host-guest complexes, but simulating larger systems can be challenging. Here a modular approach allows simulation of a neocarcerand whose complexation is enabled by the guest-induced
Externí odkaz:
https://doaj.org/article/ee9fc3bdb3504feca42a7b8411a21741
Autor:
Gerard W. Dougherty, Katsutoshi Mizuno, Tabea Nöthe-Menchen, Yayoi Ikawa, Karsten Boldt, Asaf Ta-Shma, Isabella Aprea, Katsura Minegishi, Yuan-Ping Pang, Petra Pennekamp, Niki T. Loges, Johanna Raidt, Rim Hjeij, Julia Wallmeier, Huda Mussaffi, Zeev Perles, Orly Elpeleg, Franziska Rabert, Hidetaka Shiratori, Stef J. Letteboer, Nicola Horn, Samuel Young, Timo Strünker, Friederike Stumme, Claudius Werner, Heike Olbrich, Katsuyoshi Takaoka, Takahiro Ide, Wang Kyaw Twan, Luisa Biebach, Jörg Große-Onnebrink, Judith A. Klinkenbusch, Kavita Praveen, Diana C. Bracht, Inga M. Höben, Katrin Junger, Jana Gützlaff, Sandra Cindrić, Micha Aviram, Thomas Kaiser, Yasin Memari, Petras P. Dzeja, Bernd Dworniczak, Marius Ueffing, Ronald Roepman, Kerstin Bartscherer, Nicholas Katsanis, Erica E. Davis, Israel Amirav, Hiroshi Hamada, Heymut Omran
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
The mechanism by which adenosine monophosphate modulates dynein ATPase-mediated ciliary and flagellar beating remains obscure. Here the authors identify an axonemal module including cilia and flagella associated protein 45 that supports adenine nucle
Externí odkaz:
https://doaj.org/article/ab0a6ca10924497e88909fc70b971840
Autor:
Kaiqin Ye, Wei X. Meng, Hongbin Sun, Bo Wu, Meng Chen, Yuan-Ping Pang, Jia Gao, Hongzhi Wang, Junfeng Wang, Scott H. Kaufmann, Haiming Dai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Mitochondrial apoptosis is controlled by BCL2 family proteins, and the BH3-only proteins often act as sensors that transmit apoptotic signals. Here the authors show how the BH3-only proteins BMF and HRK can directly activate the BCL2 protein BAK and
Externí odkaz:
https://doaj.org/article/cc7dbbdb162b4e9e8b2fa1674205cb01
Autor:
Yuan-Ping Pang, Marta Casal Moura, Gwen E. Thompson, Darlene R. Nelson, Amber M. Hummel, Dieter E. Jenne, Daniel Emerling, Wayne Volkmuth, William H. Robinson, Ulrich Specks
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mutants of a catalytically inactive variant of Proteinase 3 (PR3)—iPR3-Val103 possessing a Ser195Ala mutation relative to wild-type PR3-Val103—offer insights into how autoantigen PR3 interacts with antineutrophil cytoplasmic antibodies (ANCAs) in
Externí odkaz:
https://doaj.org/article/315a254bfbd1410fbcbda94f11de70d8
Autor:
Liang Zhang, Song Zhang, Izumi Maezawa, Sergey Trushin, Paras Minhas, Matthew Pinto, Lee-Way Jin, Keshar Prasain, Thi D.T. Nguyen, Yu Yamazaki, Takahisa Kanekiyo, Guojun Bu, Benjamin Gateno, Kyeong-Ok Chang, Karl A. Nath, Emirhan Nemutlu, Petras Dzeja, Yuan-Ping Pang, Duy H. Hua, Eugenia Trushina
Publikováno v:
EBioMedicine, Vol 2, Iss 4, Pp 294-305 (2015)
Development of therapeutic strategies to prevent Alzheimer's disease (AD) is of great importance. We show that mild inhibition of mitochondrial complex I with small molecule CP2 reduces levels of amyloid beta and phospho-Tau and averts cognitive decl
Externí odkaz:
https://doaj.org/article/89446c32603a429e97abaf9d89ef71a0
Autor:
Yuan-Ping Pang
Publikováno v:
Heliyon, Vol 2, Iss 9 (2016)
Predicting crystallographic B-factors of a protein from a conventional molecular dynamics simulation is challenging, in part because the B-factors calculated through sampling the atomic positional fluctuations in a picosecond molecular dynamics simul
Externí odkaz:
https://doaj.org/article/66999a3fd8cf4b37a416ba48b640e22e
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32288 (2012)
Since the report of a paralogous acetylcholinesterase (AChE, EC3.1.1.7) gene in the greenbug (Schizaphis graminum) in 2002, two different AChE genes (Ace1 and Ace2) have been identified in each of at least 27 insect species. However, the gene models
Externí odkaz:
https://doaj.org/article/a136368f81af42569646404129166f95
Autor:
Yuan-Ping Pang, Jewn Giew Park, Shaohua Wang, Anuradha Vummenthala, Rajesh K Mishra, John E McLaughlin, Rong Di, Jennifer Nielsen Kahn, Nilgun E Tumer, Laszlo Janosi, Jon Davis, Charles B Millard
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17883 (2011)
Ribosome-inactivating proteins (RIPs) are toxic because they bind to 28S rRNA and depurinate a specific adenine residue from the α-sarcin/ricin loop (SRL), thereby inhibiting protein synthesis. Shiga-like toxins (Stx1 and Stx2), produced by Escheric
Externí odkaz:
https://doaj.org/article/53849408323445f0af51c1cb09d5cbd0
Autor:
Yuan-Ping Pang, Jon Davis, Shaohua Wang, Jewn Giew Park, Madhusoodana P Nambiar, James J Schmidt, Charles B Millard
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10129 (2010)
Botulinum neurotoxin serotype A (BoNTA) causes a life-threatening neuroparalytic disease known as botulism that could afflict large, unprotected populations if the toxin were employed in an act of bioterrorism. Current post-exposure therapy is limite
Externí odkaz:
https://doaj.org/article/766b09858f2d41ee8f6c07a5a554572f