Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Yuan-Jia Hu"'
Autor:
Ke-Gang Linghu, Tian Zhang, Guang-Tao Zhang, Peng Lv, Wen-Jun Zhang, Guan-Ding Zhao, Shi-Hang Xiong, Qiu-Shuo Ma, Ming-Ming Zhao, Meiwan Chen, Yuan-Jia Hu, Chang-Sheng Zhang, Hua Yu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 3, Pp 401-415 (2024)
Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) by Kelch-like ECH-associated protein 1 (Keap1) alkylation plays a central role in anti-inflammatory therapy. However, activators of Nrf2 through alkylation of Keap1-Kelch domain have no
Externí odkaz:
https://doaj.org/article/f75993c98ed24cf58861ad94efe72201
Autor:
Xiao-Fei Yin, Taoyu Ye, Han-Lin Chen, Junyan Liu, Xue-Feng Mu, Hao Li, Jun Wang, Yuan-Jia Hu, Hongzhi Cao, Wen-Quan Kang
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT In recent years, most studies on the gut microbiome have primarily focused on feces samples, leaving the microbial communities in the intestinal mucosa relatively unexplored. To address this gap, our study employed shotgun metagenomics to an
Externí odkaz:
https://doaj.org/article/0c827232f6c74f909345af79eb541d54
Autor:
Dai-yan Zhang, Wen-qing Cui, Ling Hou, Jing Yang, Li-yang Lyu, Ze-yu Wang, Ke-Gang Linghu, Wen-bin He, Hua Yu, Yuan-jia Hu
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-17 (2023)
Abstract Background The identification of chemical–target interaction is key to pharmaceutical research and development, but the unclear materials basis and complex mechanisms of traditional medicine (TM) make it difficult, especially for low-conte
Externí odkaz:
https://doaj.org/article/c5dec50bcdee45328144865789a4797b
Autor:
Yu Chen, Shi-Hang Xiong, Fei Li, Xiang-Jun Kong, De-Fang Ouyang, Ying Zheng, Hua Yu, Yuan-Jia Hu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 150-161 (2022)
Implementing small interfering RNA (siRNA) is a promising therapy because it silences disease-related genes theoretically. However, the efficient delivery of siRNA is challenging, which limits its therapeutic applications. Various pharmaceutical deli
Externí odkaz:
https://doaj.org/article/658bd279af294175a541059e910a09b4
Autor:
Ke-Gang Linghu, Guan-Ding Zhao, Dai-Yan Zhang, Shi-Hang Xiong, Guo-Ping Wu, Li-Yu Shen, Wen-Qing Cui, Tian Zhang, Yuan-Jia Hu, Bing Guo, Xiang-Chun Shen, Hua Yu
Publikováno v:
Molecules, Vol 28, Iss 10, p 4241 (2023)
Rheumatoid arthritis (RA) is a chronic autoimmune disease triggered by a cascading inflammatory response. Sigesbeckia Herba (SH) has long been utilized as a traditional remedy to alleviate symptoms associated with rheumatism. Our previous study found
Externí odkaz:
https://doaj.org/article/a5edcfc34cf34de9a2905e4d47dc2cb0
Autor:
Meng-Die Yang, Xiao-Le Chen, Xue-Qing Hu, Xiao-Zheng Xie, Wen-Jun Zhou, Chun-Gen Zhou, Bin Jiang, Qing Ji, Qi Li, Peng Wang, Zhi-Qiang Meng, Wen-Hai Wang, Yuan-Jia Hu, Shi-Bing Su
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 5, Iss 2, Pp 81-87 (2019)
Objective: The objective of the study is to explore the traditional Chinese medicine (TCM) syndrome distribution in colorectal cancer (CRC) and its correlation with treatment methods and clinical laboratory indicators. Materials and Methods: Using th
Externí odkaz:
https://doaj.org/article/497138af469a475da76911c9319e23c6
Autor:
Xue Hua, Hui-Jie Hong, Dai-Yan Zhang, Qiao Liu, Fong Leong, Qi Yang, Yuan-Jia Hu, Xiao-Jia Chen
Publikováno v:
Molecules, Vol 27, Iss 4, p 1155 (2022)
In this study, a high-performance thin layer chromatography (HPTLC) method by two step gradient elution with two mobile phases was developed for the simultaneous analysis of seven constituents in Ophiopogonis Radix. The chromatography was performed o
Externí odkaz:
https://doaj.org/article/83f3734acf7d450897aaab5b495cc837
Autor:
Qian Zhang, Ya-Li Wang, Die Gao, Liang Cai, Yi-Yao Yang, Yuan-Jia Hu, Feng-Qing Yang, Hua Chen, Zhi-Ning Xia
Publikováno v:
Pharmaceutical Biology, Vol 56, Iss 1, Pp 67-75 (2018)
Context: Selaginella tamariscina (P. Beauv.) Spring (Selaginellaceae) (ST) has been widely used in China as a medicine for improving blood circulation. However, its processed product, S. tamariscina carbonisatus (STC), possesses opposite haemostatic
Externí odkaz:
https://doaj.org/article/ca423a376b7940a8946d3e26b8105516
Publikováno v:
Molecules, Vol 26, Iss 23, p 7293 (2021)
In this study; a spectrum–effect relationship analysis combined with a high-performance liquid chromatography–mass spectrometry (LC–MS) analysis was established to screen and identify active components that can inhibit thrombin and factor Xa (T
Externí odkaz:
https://doaj.org/article/c5bdef9bdb034306bd4a651104a036e5
Autor:
Chun-Hong Li, Cen Chen, Qian Zhang, Chen-Ning Tan, Yuan-Jia Hu, Peng Li, Jian-Bo Wan, Gang Feng, Zhi-Ning Xia, Feng-Qing Yang
Publikováno v:
Pharmaceutical Biology, Vol 55, Iss 1, Pp 76-87 (2017)
Context: Corydalis yanhusuo W.T. Wang (Papaveraceae) (Rhizoma Corydalis) showed inhibitory effects on rabbit platelet aggregation induced by ADP, thrombin (THR) or arachidonic acid (AA). Objective: This study separates and identifies the possible tar
Externí odkaz:
https://doaj.org/article/07319bf4a64e4813a44232c73e252683