Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Yuan Ying, Jiang"'
Autor:
Feng Yang, Eduardo F. C. Scopel, Hao Li, Liu-liu Sun, Nora Kawar, Yong-bing Cao, Yuan-Ying Jiang, Judith Berman
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Antifungal drug tolerance is a response distinct from resistance, in which cells grow slowly above the MIC. Here, we found that the majority (69.2%) of 133 Candida albicans clinical isolates, including standard lab strain SC5314, exhibited t
Externí odkaz:
https://doaj.org/article/80d6195302b9458ea579b114577669b8
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Candida parapsilosis is an emerging major human fungal pathogen. Echinocandins are first-line antifungal drugs for the treatment of invasive Candida infections. In clinical isolates, tolerance to echinocandins in Candida species is mostly due to poin
Externí odkaz:
https://doaj.org/article/611e6a2d208e49ddb61c559a297e008d
Autor:
Hao Li, Ming-xing Miao, Cheng-lin Jia, Yong-bing Cao, Tian-hua Yan, Yuan-ying Jiang, Feng Yang
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Candida albicans is a prevalent, opportunistic human fungal pathogen. It usually dwells in the human body as a commensal, however, once in its pathogenic state, it causes diseases ranging from debilitating superficial to life-threatening systemic inf
Externí odkaz:
https://doaj.org/article/4dad46fe52d04300a65d86f1473ea432
Autor:
Yu Zhang, Yan-Chao Liu, Si-Min Chen, Hui Zong, Wei-Tong Hou, Xi-Ran Qiu, Shi-Yu Guo, Yu-Fang Sun, Yuan-Ying Jiang, Mao-Mao An, Hui Shen
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Recent decades have seen a significant increase in invasive fungal infections, resulting in unacceptably high mortality rates. Anidulafungin (AN) is the newest echinocandin and appears to have several advantages over existing antifungals. However, it
Externí odkaz:
https://doaj.org/article/31713cb1c193480b87b91e08b772d192
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Candida species are the most common human fungal pathogens worldwide. Although C. albicans remains the predominant cause of candidiasis, infections caused by non-albicans Candida species, including C. parapsilosis, are increasing. In C. albi
Externí odkaz:
https://doaj.org/article/829813d8cd264717b426ec7797932494
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT The high morbidity and mortality of cryptococcal meningitis is due to the limited range of therapeutic options: only three classes of antifungal drugs are available (polyenes [amphotericin B], azoles [fluconazole], and pyrimidine analogues [
Externí odkaz:
https://doaj.org/article/e187214c86ed473f8539cb99c8e6a344
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT Candida albicans is a prevalent opportunistic human fungal pathogen for which treatment is limited to only four main classes of antifungal drugs, with the azole and echinocandin classes being used most frequently. Drug tolerance, the ability
Externí odkaz:
https://doaj.org/article/69d66f869bbf419987f66096995318a1
Autor:
Feng Yang, Vladimir Gritsenko, Yaniv Slor Futterman, Lu Gao, Cheng Zhen, Hui Lu, Yuan-ying Jiang, Judith Berman
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT How cells exposed to one stress are later able to better survive other types of stress is not well understood. In eukaryotic organisms, physiological and pathological stresses can disturb endoplasmic reticulum (ER) function, resulting in “
Externí odkaz:
https://doaj.org/article/049ece0840e44c8792496e6c6d300248
Autor:
Si-Min Chen, Zui Zou, Shi-Yu Guo, Wei-Tong Hou, Xi-Ran Qiu, Yu Zhang, Li-Jun Song, Xin-Yu Hu, Yuan-Ying Jiang, Hui Shen, Mao-Mao An
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2417-2432 (2020)
ABSTRACTCandida albicans is a common fungal pathogen in humans that colonizes the skin and mucosal surfaces of the majority healthy individuals. How C. albicans disseminates into the bloodstream and causes life-threatening systemic infections in immu
Externí odkaz:
https://doaj.org/article/cfcfe81d0baf426287c10c45a37cca8b
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
A gradual rise in immunocompromised patients over past years has led to the increasing incidence of invasive fungal infections. Development of effective fungicides can not only provide new means for clinical treatment, but also reduce the occurrence
Externí odkaz:
https://doaj.org/article/1d8494ef8b8a4eb28cd5c6242c416446