Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Yuan Liu Chen"'
Publikováno v:
Communications Engineering, Vol 3, Iss 1, Pp 1-12 (2024)
Abstract Atomic Force Microscopy (AFM) is a widely employed tool for micro- and nanoscale topographic imaging. However, conventional AFM scanning struggles to reconstruct complex 3D micro- and nanostructures precisely due to limitations such as incom
Externí odkaz:
https://doaj.org/article/62e1e70b35ab42389157669ae3c66266
Publikováno v:
AIP Advances, Vol 14, Iss 9, Pp 095209-095209-11 (2024)
Subsurface detection using contact resonance atomic force microscopy (CR-AFM) has been well-documented and proven capable of nondestructively detecting subsurface defects at depths of hundreds of nanometers. In CR-AFM, the frequency of the contact re
Externí odkaz:
https://doaj.org/article/2761b8a1bf524c81ab579b1abbd8ba82
Autor:
Lee-Yuan Liu-Chen, Peng Huang
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Kappa opioid receptor (KOR) agonists are potentially useful as analgesic and anti-pruritic agents, for prevention and treatment of substance use disorders, and for treatment of demyelinating diseases. However, side effects of KOR agonists, including
Externí odkaz:
https://doaj.org/article/703df32d492a45cc95efba73c007d405
Autor:
Xiangdang Shi, Eva von Weltin, Emma Fitzsimmons, Chau Do, Carolina Caban Rivera, Chongguang Chen, Lee-Yuan Liu-Chen, Ellen M. Unterwald
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Mechanistic target of rapamycin (mTOR) C1 and its downstream effectors have been implicated in synaptic plasticity and memory. Our prior work demonstrated that reactivation of cocaine memory engages a signaling pathway consisting of Akt, glycogen syn
Externí odkaz:
https://doaj.org/article/9ce6582218524563975336a5db5daf95
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Selective kappa opioid receptor (KOR) agonists are promising antipruritic agents and analgesics. However, clinical development of KOR agonists has been limited by side effects, including psychotomimetic effects, dysphoria, and sedation, except for na
Externí odkaz:
https://doaj.org/article/b6b3def666d547b68d79b7c05e40fed6
Autor:
Zachary W. Reichenbach, Kelly DiMattio, Suren Rajakaruna, David Ambrose, William D. Cornwell, Ronald J. Tallarida, Thomas Rogers, Lee-Yuan Liu-Chen, Ronald F. Tuma, Sara Jane Ward
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Acutely, non-selective cannabinoid (CB) agonists have been shown to increase morphine antinociceptive effects, and we and others have also demonstrated that non-selective CB agonists attenuate morphine antinociceptive tolerance. Activation of cannabi
Externí odkaz:
https://doaj.org/article/978a1c3db7cf456fbd08ebf0eadc29e8
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Objective Selective kappa opioid receptor (KOR) agonists were shown to produce a dose-dependent depression of brain-stimulation reward (BSR) in the rat intracranial self-stimulation (ICSS) tests. However, limited studies using mice produced
Externí odkaz:
https://doaj.org/article/b436467175e6445ab3432dfcd9084fbb
Autor:
Juliet Mengaziol, Amelia D Dunn, Gregory Salimando, Lisa Wooldridge, Jordi Crues-Muncunill, Darrell Eacret, Chongguang Chen, Kathryn Bland, Lee-Yuan Liu-Chen, Michelle E Ehrlich, Gregory Corder, Julie A Blendy
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0270317 (2022)
Key targets of both the therapeutic and abused properties of opioids are μ-opioid receptors (MORs). Despite years of research investigating the biochemistry and signal transduction pathways associated with MOR activation, we do not fully understand
Externí odkaz:
https://doaj.org/article/466f545ecc3444c2ab07f20e19c44050
Publikováno v:
Sensors, Vol 22, Iss 24, p 9906 (2022)
This paper presents a fiber-based chromatic dispersion probe for the simultaneous measurement of dual-axis absolute and relative displacement with nanometric resolutions. The proposed chromatic dispersion probe is based on optical dispersion. In the
Externí odkaz:
https://doaj.org/article/5388af7903f5431ea99387efb1502fb2
Publikováno v:
Sensors, Vol 23, Iss 1, p 51 (2022)
In this paper, a fiber-based chromatic dispersion probe for simultaneous measurement of X-axis and Z-axis displacements with nanometric resolutions by using the full width at half maxima (FWHM) of the detected spectral signal has been proposed and de
Externí odkaz:
https://doaj.org/article/6d89d92beee34b8cb2005dc06d8d4639