Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Yuan Di C. Halvorsen"'
Autor:
Jason B. Harris, Stephen B. Calderwood, Peng Xu, Jeesun Yun, Byungman Lee, Firdausi Qadri, Taufiqur Rahman Bhuiyan, Edward T. Ryan, Somyoung Cho, Chankyu Lee, Julia Lynch, Mohammad Kamruzzaman, Smriti Verma, Meagan Kelly, Yoonhee Whang, Suhi Jeon, Pavol Kováč, Minchul Park, Daniel T. Leung, Yuan-Di C. Halvorsen, Ravi Ganapathy, Richelle C. Charles, Willie F. Vann
Publikováno v:
Vaccine
There is a need to develop cholera vaccines that are protective in young children under 5 years of age, which induce long-term immunity, and which can be incorporated into the Expanded Programme of Immunization (EPI) in cholera-endemic countries. The
Autor:
Sebastian Unizony, Zsofia D. Drobni, Cory A. Perugino, Deborah S. Collier, Janeth Yinh, Chana A. Sacks, Brian C. Healy, John H. Stone, Ana D. Fernandes, Michael Dougan, Allison K. Scherer, Kathryn Bowman, Harry M Schrager, Crystal M. North, Michael K. Mansour, Nina Lin, Eric A. Meyerowitz, Sarah Nikiforow, Amna Zafar, Rachel Wallwork, Mark Matza, Yuan Di C. Halvorsen, Jorge Fleisher, Jonathan Dau, Michael D. Pincus, Arthur Y. Kim, Matthew J. Frigault, Brittany Weber, David S. Huckins, Ana Maria Bensaci, Liam Harvey, Ruta Shah, Megan Lockwood, Tara K. Thurber, Pritha Sen, Manish Sagar, Andrea S. Foulkes, Tomas G. Neilan, Zeina Dagher, Nora Horick, Ann E. Woolley, Minna J. Kohler, Naomi Serling-Boyd, Sara R. Schoenfeld, Matthew Axelrod, Caroline Cubbison, Marcy B. Bolster, Kristin M. D’Silva
Publikováno v:
New England Journal of Medicine
BACKGROUND: The efficacy of interleukin-6 receptor blockade in hospitalized patients with coronavirus disease 2019 (Covid-19) who are not receiving mechanical ventilation is unclear. METHODS: We performed a randomized, double-blind, placebo-controlle
Autor:
Yuan-Di C. Halvorsen, Geoffrey A. Walford, Mason W. Freeman, Heidy Russell, Monica Massaro, Tara K. Thurber
Publikováno v:
Diabetes, Obesity and Metabolism. 22:566-573
AIM To compare the safety and efficacy of bexagliflozin administered as monotherapy at three dosage strengths over a 12-week period to patients with type 2 diabetes who were either naive to pharmacotherapy or were previously prescribed one oral hypog
Autor:
Yuan-Di C. Halvorsen, Robert P Aftring, Geoffrey A. Walford, Joseph M. Massaro, Mason W. Freeman
Publikováno v:
Diabetes, Obesity and Metabolism. 21:2496-2504
AIM To explore the safety and effectiveness of extended exposure to bexagliflozin as a monotherapy for type 2 diabetes. METHODS Adults with diabetes (n = 288) from the USA, Colombia and Mexico were randomized 1:1 to receive bexagliflozin (20 mg) or p
Publikováno v:
Diabetes, Obesity and Metabolism. 21:2248-2256
AIM To compare the relative safety and effectiveness of bexagliflozin and sitagliptin as adjuncts to metformin for the treatment of adults with type 2 diabetes. METHODS Participants (n = 386) were randomized to receive bexagliflozin (20 mg) or sitagl
Publikováno v:
Diabetes. 69
Bexagliflozin is a potent and selective sodium glucose co-transporter 2 inhibitor. To evaluate the safety and effectiveness of bexagliflozin as an adjunct to metformin for the treatment of type 2 diabetes mellitus, participants (317) were randomized
Autor:
Mason W. Freeman, Eldrin F. Lewis, Matthew C. Riddle, Paul Lock, Yuan-Di C. Halvorsen, John J.V. McMurray, Joseph M. Massaro, Scott D. Solomon
Publikováno v:
Diabetes. 69
Bexagliflozin (bexa) is a potent and selective inhibitor of SGLT2. To demonstrate its effects in patients (pts) at increased risk of cardiovascular (CV) events, pts with type 2 diabetes (T2D) ≥40 years old with HbA1c 7.5-11 % and eGFR ≥45 were en
Autor:
Jeffrey M. Gimble, Yuan Di C. Halvorsen, Farshid Guilak, Laura Aust, William O. Wilkison, Amy Kloster, Blythe H. Devlin, Sandra J. Foster, Tracey V. Du Laney, Kevin C. Hicok, Robert W. Storms, Anindita Sen, Lyndon F. Cooper, Henry E. Rice
Publikováno v:
Stem Cell Therapy for Autoimmune Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f1dfca6ed006ecc992e8cfa65d83916
https://doi.org/10.1201/9780367813895-5
https://doi.org/10.1201/9780367813895-5
Autor:
Ajith Welihinda, Geoff E Stilwell, Wenbin Zhang, Xiaoyan Li, Haifeng Ding, Yuan-Di C. Halvorsen, Yuan Lu
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 50(5)
Bexagliflozin is a C-aryl glucoside inhibitor of human sodium-glucose linked transporter 2 (SGLT2) that undergoes oxidation and glucuronidation to form six principal metabolites in humans.In vitro metabolism by human liver microsomes and recombinant