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Desarrollo de un modelo computacional del sitio activo de la metionina sintasa

Autor: Yuan Chen, Natalia

Las transferencias de grupos metilo resultan de interés a nivel biológico por su influencia en el mantenimiento de la integridad del material genético. En los seres vivos, esta reacción se lleva a cabo por medio de complejos enzimáticos. Un sist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1205::3509e05655585292da00203663841a9b
http://repository.icesi.edu.co/biblioteca_digital/handle/10906/83848

Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects In Vitro and Neuroprotective Effects in a Pharmacological Alzheimer's Disease Mouse Model.

Autor: He F; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany., Chou CJ; Department of Drug Discovery and Biomedical Sciences, South Carolina College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, United States., Scheiner M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany., Poeta E; Department of Pharmacy and Biotechnologies, University of Bologna, Via Selmi 3, Bologna 40126, Italy., Yuan Chen N; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany., Gunesch S; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany., Hoffmann M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany., Sotriffer C; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany., Monti B; Department of Pharmacy and Biotechnologies, University of Bologna, Via Selmi 3, Bologna 40126, Italy., Maurice T; MMDN, Univ Montpellier, EPHE, INSERM, Montpellier 34095, France., Decker M; Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg, Am Hubland, Würzburg 97074, Germany.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 Apr 08; Vol. 64 (7), pp. 3794-3812. Date of Electronic Publication: 2021 Mar 26.