Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Yuan‐Soon Ho"'
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-16 (2024)
Abstract Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They mediate the exchange of substances between cells,thereby affecting biological properties and activities of recip
Externí odkaz:
https://doaj.org/article/8a0ab0a760f14f57b735f17bd67c6a3a
Autor:
You-Cheng Liao, Tzu-Chun Cheng, Shih-Hsin Tu, Jungshan Chang, Peixuan Guo, Li-Ching Chen, Yuan-Soon Ho
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 351-366 (2023)
Triple-negative breast cancer (TNBC) is highly aggressive with a poor prognosis because of a lack of cell markers as drug targets. α9-Nicotinic acetylcholine receptor (nAChR) is expressed abundantly in TNBC; thus, it is a valuable biomarker for TNBC
Externí odkaz:
https://doaj.org/article/a18fa65abcf64390b5496800e762520a
Autor:
Ching-Shui Huang, Ming-Lin Tsai, Tzu-Pin Lu, Chao-Chiang Tu, Chih-Yi Liu, Chi-Jung Huang, Yuan-Soon Ho, Shih-Hsin Tu, Eric Y. Chuang, Ling-Ming Tseng, Chi-Cheng Huang
Publikováno v:
Journal of the Formosan Medical Association, Vol 121, Iss 10, Pp 1945-1955 (2022)
Background/purpose: Previously we had identified concurrent genes, which highlighted the interplay between copy number variation (CNV) and differential gene expression (GE) for Han Chinese breast cancers. The merit of the approach is to discovery bio
Externí odkaz:
https://doaj.org/article/3f26c72a3c8a4622a4e0f0a766e5e7b0
Autor:
Wen‐Jui Lee, Li‐Ching Chen, Juo‐Han Lin, Tzu‐Chun Cheng, Ching‐Chuan Kuo, Chih‐Hsiung Wu, Hui‐Wen Chang, Shih‐Hsin Tu, Yuan‐Soon Ho
Publikováno v:
Cancer Medicine, Vol 8, Iss 10, Pp 4821-4835 (2019)
Abstract Neuroblastoma is the second most common pediatric malignancy and has a high rate of spontaneous remission. Uncovering the mechanisms underlying neuroblastoma cell differentiation is critical for therapeutic purposes. A neuroblastoma cell lin
Externí odkaz:
https://doaj.org/article/7db11a9223b44eb8bb62dcd816d0ed33
Autor:
Chun-Yu Lin, Chia-Hwa Lee, Yi-Hsuan Chuang, Jung-Yu Lee, Yi-Yuan Chiu, Yan-Hwa Wu Lee, Yuh-Jyh Jong, Jenn-Kang Hwang, Sing-Han Huang, Li-Ching Chen, Chih-Hsiung Wu, Shih-Hsin Tu, Yuan-Soon Ho, Jinn-Moon Yang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker developm
Externí odkaz:
https://doaj.org/article/34ff9a3b0c684e9db11e11f9aee3a016
Autor:
Kuan-Hsun Wu, Wen-Jui Lee, Tzu-Chun Cheng, Hui-Wen Chang, Li-Ching Chen, Chia-Chang Chen, Hsiu-Man Lien, Teng-Nan Lin, Yuan-Soon Ho
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Apiole was isolated from the leaves of various plants and vegetables and has been demonstrated to inhibit human colon cancer cell (COLO 205 cells) growth through induction of G0/G1 cell cycle arrest and apoptotic cell death. This
Externí odkaz:
https://doaj.org/article/254c8b61d0334ed8ba13d954ccc3c913
Autor:
Juo-Han Lin, Wen-Jui Lee, Han-Chung Wu, Chih-Hsiung Wu, Li-Ching Chen, Chi-Cheng Huang, Hang-Lung Chang, Tzu-Chun Cheng, Hui-Wen Chang, Chi-Tang Ho, Shih-Hsin Tu, Yuan-Soon Ho
Publikováno v:
Cell Adhesion & Migration, Vol 13, Iss 1, Pp 121-138 (2019)
The function of small G protein signalling modulators (SGSM1/2/3) in cancer remains unknown. Our findings demonstrated that SGSM2 is a plasma membrane protein that strongly interacted with E-cadherin/β-catenin. SGSM2 downregulation enhanced the phos
Externí odkaz:
https://doaj.org/article/46865f48a6b342c4a92b3927f29245c7
Autor:
Tzu-Chun Kan, Mei-Hsiang Lin, Chun-Chia Cheng, Jeng-Wei Lu, Ming-Thau Sheu, Yuan-Soon Ho, Sri Rahayu, Jungshan Chang
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 839 (2022)
Cisplatin is one of the most common therapeutics used in treatments of several types of cancers. To enhance cisplatin lipophilicity and reduce resistance and side effects, a polyfluorinated bipyridine-modified cisplatin analogue, dichloro[4,4’-bis(
Externí odkaz:
https://doaj.org/article/544131621a934047b7c9de05ddc9bc17
Autor:
Yu-Ya Hwang, Yuan-Soon Ho
Publikováno v:
Food Science and Human Wellness, Vol 7, Iss 3, Pp 205-208 (2018)
Respiratory diseases have been a major health concern for human beings since several decades. Soothing the irritated nasal passages and airways had been a mutual necessity in multiple ancient cultures. In ancient China, herbs were largely used to hel
Externí odkaz:
https://doaj.org/article/5e6c68b575f74cea8c44d27783f8dee5
Autor:
Hui-Tien Liu, Yuan-Soon Ho
Publikováno v:
Food Science and Human Wellness, Vol 7, Iss 2, Pp 134-137 (2018)
Numerous studies have shown that curcumin, a natural compound, exerts anticancer effects by inhibiting cancer cell proliferation and metastasis and by inducing cell cycle arrest and apoptosis. In particular, curcumin exhibits potent inhibitory effect
Externí odkaz:
https://doaj.org/article/be353745b21f491b8d17e96b23c5c3ab