Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yu. Yu. Silaeva"'
Autor:
D. B. Kazansky, M. S. Vagida, Yu. Yu. Silaeva, A. A. Kalinina, M. A. Zamkova, L. M. Khromykh, N. А. Persiyantseva, L. Kh. Jolokhava
Publikováno v:
Успехи молекулярной онкологии, Vol 4, Iss 4, Pp 42-48 (2017)
Background. Wide use of glucocorticoids therapy for neoplasms, autoimmune diseases and allergies is associated with suppression of adaptive immunity that requires profound study of their immunoregulatory properties and immunotoxicity.Results. In this
Externí odkaz:
https://doaj.org/article/f613546b9b5148f9b03a6dc88c122476
Autor:
D. B. Kazanskiy, Yu. Yu. Silaeva, A. A. Kalinina, M. A. Zamkova, L. M. Khromykh, N. A. Persiyantseva, L. Kh. Dzholokhava
Publikováno v:
Успехи молекулярной онкологии, Vol 4, Iss 3, Pp 21-26 (2017)
In wide number of approaches to treatment of cancer immunotherapy plays special role. This approach exploits capabilities of immune system to support genetic constancy of different cells and tissues of the organism. Immunotherapy is designed to induc
Externí odkaz:
https://doaj.org/article/5f5f058a900d4da498433ada19aee46b
Autor:
D. B. Kazanskiy, Yu. Yu. Silaeva, A. A. Kalinina, M. A. Zamkova, L. M. Khromykh, N. A. Persiyantseva, L. Kh. Dzholokhava
Publikováno v:
Успехи молекулярной онкологии, Vol 3, Iss 1, Pp 14-27 (2016)
Findings in experimental oncology in beginning of last century and subsequent achievements of genetics of tissue compatibility resulted in divergence of transplantational immunology and oncoimmunology. However, central achievements of both scientific
Externí odkaz:
https://doaj.org/article/8e8b8cefc73549549c2423a2aeb50fd9
Publikováno v:
Acta Naturae
The peripheral T-cell pool consists of several, functionally distinct populations of CD8+ T cells. CD44 and CD62L are among the major surface markers that allow us to define T-cell populations. The expression of these molecules depends on the functio
Publikováno v:
Doklady. Biochemistry and Biophysics
Abstract Under conditions of lymphopenia, T lymphocytes proliferate and acquire a surface activation phenotype, which in many respects is similar to the phenotype of true memory T cells. We investigated the phenotypic features of the CD8+ T-cell popu
Publikováno v:
Acta Naturae
Cyclophilin A (CypA) is a multifunctional protein that exhibits an isomerase activity and exists in the intracellular and secretory forms. Secretory CypA promotes regeneration of the hematopoietic and the immune systems of an organism by stimulating
Publikováno v:
Russian Journal of Developmental Biology. 49:356-361
The technology of creating genetically modified animals (placental mammals) by microinjection into the pronucleus of a fertilized egg suggests, as one of the key stages, the transplantation of early embryos into female recipients. However, there is a
Autor:
L. Kh. Dzholokhava, N. A. Persiyantseva, A A Kalinina, L. M. Khromykh, D. B. Kazanskiy, Yu Yu Silaeva, M. A. Zamkova
Publikováno v:
Uspehi Molekulârnoj Onkologii, Vol 4, Iss 3, Pp 21-26 (2017)
In wide number of approaches to treatment of cancer immunotherapy plays special role. This approach exploits capabilities of immune system to support genetic constancy of different cells and tissues of the organism. Immunotherapy is designed to induc
Autor:
E. R. Sadchikova, Yu. Yu. Silaeva, A. V. Deikin, Anastasia A Kalinina, T G Ermolkevich, L. M. Khromykh, D. B. Kazansky, Murad Vagida, I. L. Goldman
Publikováno v:
Biochemistry (Moscow). 78:549-559
Peripheral T lymphocytes can be subdivided into naïve and antigen-experienced T cells. The latter, in turn, are represented by effector and central memory cells that are identified by different profiles of activation markers expression, such as CD44
Autor:
T G Ermolkevich, E. V. Maryukhnich, D. B. Kazansky, I. L. Goldman, E. R. Sadchikova, A. V. Deikin, Ekaterina Zvezdova, Yu. Yu. Silaeva, Murad Vagida, S. G. Kadulin
Publikováno v:
Molecular Biology. 44:277-286
Transgenic animal analysis has become a key approach used to study the gene functions and to model various human diseases, including autoimmune disorders. Such disorders are caused by the activation of T-cell clones whose T-cell receptors (TCRs) have