Zobrazeno 1 - 10 of 397 pro vyhledávání: '"Yu. N. Sheinker"'
1
Metabolism of the new antiarrhythmic drug nibentan
Autor: A. I. L'vov, E. F. Kuleshova, Yu. N. Sheinker, N. P. Solov'eva, V. V. Chistyakov, O. S. Anisimova, A. P. Pleshkova
Publikováno v: Pharmaceutical Chemistry Journal. 31:344-349
Rats. Each experiment was performed with a group of 15 2 0 intact white mongrel intact rats weighing about 100 g. One day before testing, the animals were deprived of feeding and received only water. The test preparations were introduced perorally at
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81ee732ca612adcde65d6ca8bb964980
https://doi.org/10.1007/bf02464366
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3
β-(Benzofur-2-yl)-and (indol-2-yl)enamines in the Nenitzescu reaction
Autor: Vladimir G. Granik, E. K. Panisheva, T. I. Mukhanova, V. M. Lyubchanskaya, L. M. Alekseeva, Yu. N. Sheinker
Publikováno v: Tetrahedron. 53:177-184
Depending on the volume and electron-withdrawing properties of the substituents in the heterocyclic ring, reaction of β-(benzofur-2-yl)- and -(indol-2-yl)enamines with benzoquinone leads to the formation of 3-heteroarylbenzofurans, with or without a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60905b0c4a0cf7d3dd432cef2ec94a4b
https://doi.org/10.1016/s0040-4020(96)00961-1
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5
Study of metabolism of the antiviral drug arbidol by mass spectrometry, thin-layer and high-performance liquid chromatography
Autor: A. P. Pleshkova, O. S. Anisimova, S. A. Zotova, I. A. Ermachenkov, I. V. Golovanova, L. V. Frolova, Yu. N. Sheinker, V. A. Yadrovskaya, V. V. Chistyakov
Publikováno v: Pharmaceutical Chemistry Journal. 29:78-82
The metabolism of the antiviral drug arbidol was studied on rats with peroral administration. Mass spectrometry, thin-layer and high-performance liquid chromatography showed that the biotransformation of arbidol occurs with the loss of a dimethylamin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d442c51217ba85f0017e713c538386d
https://doi.org/10.1007/bf02226513
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6
Study of the metabolism of the new anti-ulcer drug quiditene [(3-quinuclidyl)-di(2-thienyl)carbinol]
Autor: S. M. Tupikina, Yu. N. Sheinker, L. N. Yakhontov, M. É. Kaminka, O. S. Anisimova, M. V. Polikarpov, E. F. Kuleshova, L. N. Koikov
Publikováno v: Pharmaceutical Chemistry Journal. 29:26-29
Thin-layer chromatography and mass spectrometry were used to study the metabolism of the new anti-ulcer drug Quiditene. After oral administration in a dose of 100 mg/kg, urine samples taken 2 h later showed no metabolites. Later samples (taken 4, 6,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::039dda03fcc719a0781f370e04654046
https://doi.org/10.1007/bf02219457
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7
Investigation of heterocycles containing nitrogen or sulfur. 48. Derivatives of 1-morpholinooxalyl-1,2-dihydrothiazolo-[5,4-b]pyridine, their structure, and reactions
Autor: L. A. Serochkina, Yu. N. Sheinker, K. F. Turchin, N. P. Solov'eva, T. S. Safonova, O. S. Anisimova, L. G. Levkovskaya, E. M. Peresleni
Publikováno v: Chemistry of Heterocyclic Compounds. 29:966-971
The structures of the products of reactions of 1-N-morpholinooxahi-1,2-dihydrothiazolo-[5,4-b]pyridine have been studied by IR, NMR, UV, and mass spectroscopy. Geometric (cis-anti) and rotational (about the CO-N amide bond) isomers of 1-N-morpholinoo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97f7f64e114faeb3c7001289d54aa57c
https://doi.org/10.1007/bf00534280
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8
Investigation of heterocycles containing nitrogen or sulfur. 47. Reactions of 1,2-dioxo-3a-alkyl-4,7-dichloroxazolidino [3,2-f]pyrido[2,3-b]-1,4-thiazines with saturated cyclic amines. synthesis and structure of derivatives of 1,2-dihydrothiazolo[5,4-b]pyridine
Autor: N. P. Solov'eva, Yu. N. Sheinker, O. S. Anisimova, K. F. Turchin, E. M. Peresleni, L. A. Serochkina, L. G. Levkovskaya, T. S. Safonova
Publikováno v: Chemistry of Heterocyclic Compounds. 29:959-965
It has been established spectroscopically that 1-N-oxalamides of 2-acyl-5-chloro-1,2-dihydrothiazolo[5,4-b] pyridine are formed in the reaction of 4,7-dichloroxazolidino[3,2-f]pyrido[2,3-b]-1,4-thiazines with morpholine, piperidine and pyrrolidine. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea45f72f0418dad597eddfbce35c892d
https://doi.org/10.1007/bf00534279
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10
Synthesis, structure, and properties, of 4a-hydroxyisoxazolidino[4,5-b]quinuclidines
Autor: Yu. N. Sheinker, V. A. Bondarenko, L. N. Yakhontov, T. Ya. Filipenko, K. F. Turchin, E. E. Mikhlina
Publikováno v: Chemistry of Heterocyclic Compounds. 29:103-108
Proton and carbon-13 NMR spectroscopy have been used to confirm the structure and establish the 4a,7a(RR/SS) configuration of 4a-hydroxyisoxazolidino[4,5-b]quinuclidines obtained by the reaction of N-arylhydroxylamines with 2-methylene-3-oxoquinuclid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63f9aedaa52e3d67fc51c617d980b8f9
https://doi.org/10.1007/bf00528646
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