Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yu. M. Parkhomenko"'
Autor:
O. S. Pavlova, A. A. Tykhomyrov, O. A. Mejenskaya, S. P. Stepanenko, L. I. Chehivska, Yu. M. Parkhomenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 4, Pp 41-49 (2019)
Long-term ethyl alcohol consumption induces a deficiency of essential nutrient thiamine (vitamin B1 ) and profoundly impairs metabolic processes in nervous tissue, resulting in structural and functional alterations in the central nervous system (CNS)
Externí odkaz:
https://doaj.org/article/f0d533ed47464c9db43b00252a07634b
Thiamine diphosphate synthesis and redox state indicator in rat brain during of B(1) hypovitaminosis
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 5, Pp 84-95 (2017)
The main aim of this study was to reveal the relationship between thiamine metabolism and the redox balance of cellular metabolism in chronic alimentary thiamine deficiency. On the experimental model of chronic alimentary thiamine deficiency (hypovit
Externí odkaz:
https://doaj.org/article/e6ea16082d5e4c8c8c514f2ef090c31e
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 2, Pp 59-67 (2013)
Oral administration of antituberculosis drugs to rats for 60 days in doses that are equivalent to clinical ones, causes changes in mRNA levels expression of liver cytochrome P-450 isoforms CYP3A2, CYP2C23, CYP2E1 and pro- and antioxidant state. Exper
Externí odkaz:
https://doaj.org/article/9c3a87bdc8634e11bf6a0d3cc4b23310
Publikováno v:
Neurophysiology. 48:429-448
The available information on the mechanisms of involvement of vitamin B1 (thiamine) in vital processes in neural cells is analyzed. It is concluded that, together with the coenzymatic functions performed by this vitamin, the latter realizes “noncoe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77120376d63ce129ef3dc4f7fd08cf59
https://doi.org/10.1007/s11062-017-9620-3
https://doi.org/10.1007/s11062-017-9620-3
Publikováno v:
Neurophysiology. 48:336-345
Vitamin В1 deficiency was modeled in rats; their daily diet during 6 weeks contained about 20% of the necessary amount of thiamine. Under these conditions, the total content of vitamin В1 (thiamine) in the liver was, on average, 18.3% of the contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b365af20d63d7f0993c7f2d4758ae56
https://doi.org/10.1007/s11062-017-9607-0
https://doi.org/10.1007/s11062-017-9607-0
Autor:
G. V. Donchenko, E. N. Gorban, O. A. Mejenskaya, L. I. Chehovskaya, S. P. Stepanenko, Yu. M. Parkhomenko
Publikováno v:
Biotechnologia Acta, Vol 8, Iss 4, Pp 63-70 (2015)
The aim of the research was to test the ability of the drug "Metovitan" to prevent the redox balance disturbance in the tissues and thiamine diphosphate irreversible oxidation upon exposure of ionizing radiation on the body. The rats were subjected t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ca5f144ff34e2ad493605baaef61e5
http://biotechnology.kiev.ua/images/stories/no4_2015/parkhomenko_4_2015.pdf
http://biotechnology.kiev.ua/images/stories/no4_2015/parkhomenko_4_2015.pdf
Autor:
G. V. Donchenko, N. Kh. Pogorelaya, A. O. Strokina, L. I. Chekhovskaya, O. R. Yanchiy, S. Y. Pylypchuk, Yu. M. Parkhomenko, S. A. Chornyi, S. P. Stepanenko
Publikováno v:
Neurophysiology. 46:1-9
We studied the sensitivity of a few reactions of thiamine metabolism in nerve cells upon the action of ethanol and acetaldehyde, as well as effects of the above-mentioned agents on vital capacity of cultured cells of different origins. Experiments we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::611c027d09e9e54e80ab13a4bbee01c2
https://doi.org/10.1007/s11062-014-9399-4
https://doi.org/10.1007/s11062-014-9399-4
Autor:
Yu. M. Parkhomenko, G. V. Donchenko, L. I. Chehovskaya, S. P. Stepanenko, O. A. Mejenskaya, E. N. Gorban
Publikováno v:
Biotechnologia Acta.
The aim of the research was to test the ability of the drug “Metovitan” to prevent the redox balance disturbance in the tissues and thiamine diphosphate irreversible oxidation upon exposure of ionizing radiation on the body. The rats were undergo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2806::cb87fdf11af0de33a22db1aad6943d87
http://cyberleninka.ru/article_covers/16051773.png
http://cyberleninka.ru/article_covers/16051773.png
Autor:
Yu. M. Parkhomenko, S. A. Chornyy
Publikováno v:
Biopolymers and Cell. 22:290-298
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa474657eb14f5782940dea93169590f
https://doi.org/10.7124/bc.00073b
https://doi.org/10.7124/bc.00073b
Publikováno v:
Neurophysiology. 33:135-139
Using preparations of synaptosomes and subsynaptosomal fractions from the rat brain, we studied the localization of thiamine-binding protein (TBP) in the subcellular structures of the neurons. In addition, we studied the distribution in synaptosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d7f2200921b13f59c2f4c11c43488c7
https://doi.org/10.1023/a:1012840417285
https://doi.org/10.1023/a:1012840417285