Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Yu. Khristichenko"'
Publikováno v:
Russian Journal of Numerical Analysis and Mathematical Modelling. 38:89-98
The paper is focused on the dependence of optimal disturbances of stable periodic solutions of time-delay systems on phases of such solutions. The results of numerical experiments with the well-known model of the dynamics of infection caused by lymph
Autor:
Andrey A. Poloznikov, Sergey V. Nikulin, Dmitry M. Hushpulian, Anna Yu. Khristichenko, Andrey I. Osipyants, Andrey F. Asachenko, Olga V. Shurupova, Svyatoslav S. Savin, Sue H. Lee, Irina N. Gaisina, Gregory R. J. Thatcher, Anthony Narciso, Eric P. Chang, Sergey V. Kazakov, Nancy Krucher, Vladimir I. Tishkov, Bobby Thomas, Irina G. Gazaryan
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 220 (2022)
To evaluate the differences in action of commercially available 2-oxoglutarate mimetics and “branched-tail” oxyquinoline inhibitors of hypoxia-inducible factor prolyl hydroxylase (HIF PHD), the inhibitors’ IC50 values in the activation of HIF1
Externí odkaz:
https://doaj.org/article/346dd9b0bc0241e5a107f57d17140f23
Publikováno v:
Медицинская иммунология, Vol 20, Iss 3, Pp 313-340 (2018)
Our understanding of anticancer immune surveillance currently serves as a basis for development of novel therapies that utilize patient’s own immune system as an anticancer agent. Previously, cancer immunotherapy mostly included non-specific immuno
Externí odkaz:
https://doaj.org/article/70bf3e70f41f401cb4a13e41f51b4853
Publikováno v:
Contemporary Mathematics. Fundamental Directions. 68:686-703
This work is devoted to the technology developed by the authors that allows one for fixed values of parameters and tracing by parameters to calculate stationary solutions of systems with delay and analyze their stability. We discuss the results of ap
Publikováno v:
Russian Journal of Numerical Analysis and Mathematical Modelling. 37:203-212
A concept of optimal disturbances of periodic solutions for a system of time-delay differential equations is defined. An algorithm for computing the optimal disturbances is proposed and justified. This algorithm is tested on the known system of four
Publikováno v:
Russian Journal of Numerical Analysis and Mathematical Modelling. 36:87-99
The paper is focused on computation of stable periodic solutions to systems of delay differential equations modelling the dynamics of infectious diseases and immune response. The method proposed here is described by an example of the well-known model
Autor:
Dmitry M. Hushpulian, Andrey A. Poloznikov, Sergey Nikulin, Irina G. Gazaryan, A. Yu. Khristichenko, T. A. Chubar
Publikováno v:
Moscow University Chemistry Bulletin. 76:114-121
The attempts to elucidate the mechanism of the hypoxic activation of erythropoietin synthesis lead to the discovery of the hypoxia inducible factor (HIF) and its stability regulation via HIF prolyl hydroxylase, iron, and α-ketoglutarate dependent di
Publikováno v:
Journal of Mathematical Sciences. 253:618-641
In this paper, we apply optimal perturbations to control mathematical models of infectious diseases expressed as systems of nonlinear differential equations with delayed independent variables. We develop the method for calculation of perturbations of
Autor:
T. A. Chubar, Vladimir I. Tishkov, Yu. Khristichenko, Irina G. Gazaryan, Dmitry M. Hushpulian, Andrey A. Poloznikov, N. A. Smirnova, A. A. Zakhariants
Publikováno v:
Moscow University Chemistry Bulletin. 75:172-178
Reporter vectors expressing of amino acid residues 16–96 and 16–85 from Neh2-domain of Nrf2 transcription factor fused to firefly luciferase have been constructed. Cell lines stably expressing the above reporter constructs as well as an earlier d
Autor:
D. V. Maltseva, O. V. Kindeeva, V. A. Petrov, G. A. Belyakova, A. Yu. Khristichenko, E N Knyazev, T. N. Gerasimenko, Sergey Nikulin
Publikováno v:
Russian Chemical Bulletin. 68:2344-2349
An in vitro placental barrier model based on human choriocarcinoma BeWo b30 cell line was considered as a method of preclinical study of the transport and toxicity of antitumor agents and other organic compounds. Low permeabilities were found for 5-f