Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yu. B. Vikharev"'
Autor:
V. B. Vasilyuk, M. V. Faraponova, A. B. Verveda, G. I. Syraeva, Yu. B. Vikharev, A. V. Popov, A. L. Kovalenko
Publikováno v:
Российский кардиологический журнал, Vol 29, Iss 8 (2024)
Aim. To study the comparative pharmacokinetics and confirmation of bioequivalence of the generic (T) and original (R) dabigatran etexilate in healthy volunteers after a single oral dose under fasted conditions.Material and methods. To confirm bioequi
Externí odkaz:
https://doaj.org/article/f0d4f2861df44468accf235d3577a562
Autor:
Elena F. Shevtsova, A. A. Ustyugov, Yu. B. Vikharev, Sergey O. Bachurin, N. A. Vasil’eva, G. V. Maleev, Vladimir O. Nebogatikov, A. Yu. Aksinenko
Publikováno v:
Russian Chemical Bulletin. 69:781-786
γ-Carboline derivatives were synthesized by the addition of fluorinated vinylpyridines to 2,6-dimethyl-2,3,4,5-tetrahydro-γ-carboline. The effect of repeated intraperitoneal injections of the synthesized derivatives on the progression of motor and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89b28e173670addde4f948c707d4fc5a
https://doi.org/10.1007/s11172-020-2833-4
https://doi.org/10.1007/s11172-020-2833-4
Autor:
Yu. B. Vikharev, I. P. Kalashnikova, V. E. Baulin, D. V. Baulin, E. A. Vikhareva, A. Yu. Tsivadze
Publikováno v:
Russian Journal of General Chemistry. 88:1786-1791
The synthetically convenient method of preparation of unexplored phosphoryl analogs of salicylic acid (2-hydroxyphenylphosphonic and 2-hydroxyphenylphosphinic acids) has been developed for the search of novel nonsteroidal anti-inflammatory drugs. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ff0a6d923477bfa2589a2ab6434e02
https://doi.org/10.1134/s1070363218090049
https://doi.org/10.1134/s1070363218090049
Autor:
O. A. Maiorova, Natalia V. Galaiko, I. A. Tolmacheva, Yu. B. Vikharev, Pavel A. Slepukhin, A. V. Nazarov, Victoria V. Grishko
Publikováno v:
Chemistry of Heterocyclic Compounds. 50:65-75
Lupane and 18αH-oleanane α-hydroximino ketones were used to synthesize derivatives condensed at ring A with a substituted azole fragment, namely, C(2)–C(3)-fused oxazoles and 1,2,3-triazoles. Triterpene isoxazoles fused at the C(1)–C(2) bond ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4065b2f4c375f3353bf90328c893771b
https://doi.org/10.1007/s10593-014-1449-8
https://doi.org/10.1007/s10593-014-1449-8
Publikováno v:
Pharmaceutical Chemistry Journal. 46:707-710
A series of 3-spiro[adamantane-2,3′-isoquinolines] were synthesized. Their neurotropic activity and cytotoxicity were evaluated. Two compounds with anxiolytic activity were found, one of which showed antitumor activity in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22a66dc89f1d5dc0d6a6c850da532ef
https://doi.org/10.1007/s11094-013-0874-9
https://doi.org/10.1007/s11094-013-0874-9
Autor:
Victoria V. Grishko, E. V. Igosheva, E. I. Boreko, Yu. B. Vikharev, I. A. Tolmacheva, O. V. Savinova, V. F. Eremin
Publikováno v:
Russian Journal of Bioorganic Chemistry. 39:186-193
Amides of four types were synthesized derived from 2,3-seco-18αH-oleanane and 2,3-secolupane mono- and dicarboxylic acids. The spectrum of diamide derivatives was expanded with C3-C3′ and C28-C28′ biscondensed amides with two A-secotriterpene ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b50cdc523f4fdf412f4b444f6c1264c
https://doi.org/10.1134/s1068162013020143
https://doi.org/10.1134/s1068162013020143
Autor:
Evgeny V. Buravlev, Lada V. Anikina, Yu. B. Vikharev, Victoria V. Grishko, I. Yu. Chukicheva, M. A. Torlopov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 38:647-651
Water-soluble sulfate polysalts of carboxymethyl cellulose and tertiary aminomethyl derivatives of 2-isobornyl-4-methylphenol were obtained. Investigations were carried out for the synthesized conjugates in vivo of anti-inflammatory activity in the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a09b21f5949394f857e7d1fab02b7d7
https://doi.org/10.1134/s1068162012040048
https://doi.org/10.1134/s1068162012040048
Autor:
Yu. B. Vikharev, Yu. V. Nelyubina, Lada V. Anikina, Vladimir V. Baranov, Ivan S. Bushmarinov, Angelina N. Kravchenko
Publikováno v:
Russian Journal of Bioorganic Chemistry. 38:550-557
A study of the neurotropic, neuroprotective, and antioxidant action of the enantiomers and racemate of 2-[(3,7-dioxo-2,4,6,8-tetraazabicyclo[3.3.0]oct-2-yl)]-4-methylthiobutanoic acid synthesized in a stereoselective reaction of (R)-, (S)-, or (R,S)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec29c6fe180d725cb1644d88ec3e7a70
https://doi.org/10.1134/s106816201205007x
https://doi.org/10.1134/s106816201205007x
Autor:
O. V. Savinova, Yu. B. Vikharev, Victoria V. Grishko, E. I. Boreko, V. F. Eremin, E. V. Igosheva, I. A. Tolmacheva
Publikováno v:
Chemistry of Natural Compounds. 48:426-431
New A-seco-lupane C-3 amide conjugates were prepared by the reaction of 28-methoxy-28-oxo-1-cyano2,3-seco-lup-20(29)-en-3-oic acid chloride with primary amines and synthetic and natural amino acids. Ethyl-N-[28-methyl-28-oxo-1-cyano-2,3-seco-lup-20(2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62ff22355b899050194859bb09c8ff35
https://doi.org/10.1007/s10600-012-0266-5
https://doi.org/10.1007/s10600-012-0266-5
Publikováno v:
Pharmaceutical Chemistry Journal. 45:712-716
Oxidation of substituted N-acyl-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolines led to the corresponding 1,2-epoxides and 1,2-diols. The synthesized 1,2-epoxides were characterized with respect to acute toxicity, cytotoxicity, analgesic acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::384aa7c6775d3ce00f67e013eebb4ef7
https://doi.org/10.1007/s11094-012-0708-1
https://doi.org/10.1007/s11094-012-0708-1