Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yu. A. Piven"'
Autor:
T. S. Khlebniсova, V. G. Zinovich, Yu. A. Piven, A. V. Baranovsky, F. A. Lakhvich, R. E. Trifonov, Yu. A. Golubeva, L. S. Klyushova, E. V. Lider
Publikováno v:
Russian Journal of General Chemistry. 93:268-277
Abstract Triazole-containing 1,5,6,7-tetrahydro-4H-indazol-4-ones and 6,7-dihydrobenzo[d]isoxazol-4(5H)-ones were synthesized by cyclocondensation of 2-[(1H-1,2,3-triazol-1-yl)acetyl]cyclohexane-1,3-diones with phenylhydrazine (4-fluorophenylhydrazin
Autor:
T. S. Khlebniсova, V. G. Zinovich, Yu. A. Piven, A. V. Baranovsky, F. A. Lakhvich, R. E. Trifonov, Yu. A. Golubeva, E. V. Lider
Publikováno v:
Russian Journal of General Chemistry. 92:359-366
Autor:
Veronica G. Zinovich, Tatyana S. Khlebnicova, Yu. A. Piven, Alexander V. Baranovsky, R. E. Trifonov, Fedor A. Lakhvich
Publikováno v:
Russian Journal of General Chemistry. 91:1438-1443
2-(Tetrazolylacetyl)cyclohexane-1,3-diones were synthesized via C-acylation of cyclohexane-1,3-diones with tetrazolylacetic acids in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride and N,N-dimethylaminopyridine in acetonit
Autor:
E. M. Tumar, O. V. Panibrat, V. G. Zinovich, Yu. A. Piven, S. E. Ogurtsova, Fedor A. Lakhvich, T. S. Khlebnikova
Publikováno v:
Pharmaceutical Chemistry Journal. 55:219-223
The cytotoxic activity of perfluoroalkyl imidazoindazoles and imidazobenzisoxazoles with respect to MCF-7 (human breast carcinoma) and HepG2 cell lines (human hepatocellular carcinoma) was studied. The imidazoindazoles exhibited significant cytotoxic
Autor:
O. V. Panibrat, É. B. Rusanov, V. G. Zinovich, Fedor A. Lakhvich, S. E. Ogurtsova, A. V. Baranovskii, T. S. Khlebnikova, Yu. A. Piven
Publikováno v:
Pharmaceutical Chemistry Journal. 54:700-706
The oximes of fluorine-containing 6,7-dihydroindazole-4,5-diones and 6,7-dihydrobenzisoxazole-4-5-diones, 5-[3-fluorobenzoyloxy)imino)]-6,6-dimethyl-3-(3-fluorophenyl)-6,7-dihydrobenz[d]]isoxazol-4(5H)-one, and 5,5-dimethyl-7-phenyl-9-(4-fluorophenyl
Autor:
Alexander V. Baranovsky, V. G. Isakova, Yu. A. Piven, T. S. Khlebnikova, V. A. Smaliak, Fedor A. Lakhvich
Publikováno v:
Russian Journal of General Chemistry. 90:746-749
Synthesis of regioisomeric 8-trifluoromethyl-4,5-dihydro-3H-imidazo[4',5':5,6]benz[1,2-d]isoxazoles and 8-trifluoromethyl-4,5-dihydro-3H-imidazo[4',5':3,4]benz[1,2-c]isoxazolones was realized by one-pot oxidation of 3-trifluromethyl-6,7-dihydrobenz[d
Autor:
Alexander E. Sorochinsky, Yu. A. Piven, Igor I. Gerus, Fedor A. Lakhvich, Tatyana S. Khlebnicova
Publikováno v:
Doklady of the National Academy of Sciences of Belarus. 63:716-720
On the example of synthesis of 4-acetylamino-3-fluoroalkyl(aryl)-4,5,6,7-tetrahydro-1,2-benzisoxazoles, the effective approach to a synthesis of novel 4-acylamino-4,5,6,7-tetrahydro-1,2-benzisoxazoles is proposed. 3-Fluoroalkyl(aryl)- 6,7-dihydro-1,2
Autor:
T. S. Khlebnikova, Fedor A. Lakhvich, I. V. Sorokina, Yu. A. Piven, T. S. Frolova, T. G. Tolstikova
Publikováno v:
Chemistry of Natural Compounds. 54:1100-1105
Conjugates of betulinic acid with 2-(fluoroacyl)cycloalkane-1,3-dione motifs were synthesized by reacting 3-chloro-2-(fluoroacyl)-2-cycloalkene-1-ones with an equivalent amount of betulinic acid aminoalkylamide hydrochlorides in the presence of Et3N
Publikováno v:
Russian Journal of Organic Chemistry. 51:650-656
Refluxing 3-perfluoroalkyl-6,7-dihydro-1H-indazol-4(5H)-ones with 4-fold excess of hydroxylamine hydrochloride in pyridine afforded their (E)-oximes. The obtained oximes were alkylated with ethyl iodide and acylated with carboxylic acids chlorides to
Publikováno v:
Russian Journal of General Chemistry. 84:465-473
The interaction of aromatic amines (4-fluorinebenzylamine, 3-trifluoromethylbenzylamine, 4-fluoroaniline, or 3,4-difluoroaniline) with either 2-acylcyclopentane-1,3-diones (fluorine-substituted or fluorine-free) or their enol derivatives (chlorovinyl