Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yu. A. Mokrushina"'
Autor:
S. A. Goncharuk, M. N. Baranova, A. S. Shcheglov, A. Yu. Gorokhovatsky, Ilia V. Yampolsky, T. V. Chepurnykh, K. V. Purtov, Natalja S. Rodionova, Valentin N. Petushkov, Yu. A. Mokrushina
Publikováno v:
Doklady. Biochemistry and Biophysics
Abstract A key component of the recently described bioluminescent system of higher fungi is luciferase, a new class of proteins. The properties of fungal luciferase and their relationship with its structure are interesting both for improving autolumi
Autor:
Arthur O. Zalevsky, Andrey V. Golovin, Yu. A. Mokrushina, Olga V. Kartseva, Alexander Zlobin, Ivan V. Smirnov
Publikováno v:
Acta Naturae. 10:121-124
In this paper, we, for the first time, describe the interaction between the butyrylcholinesterase enzyme and echothiophate, a popular model compound and an analogue of the chemical warfare agents VX and VR, at the atomistic level. Competition between
Autor:
Sofiya O. Pipiya, Ivan V. Smirnov, Stanislav S. Terekhov, Alexander G. Gabibov, V. D. Knorre, Yu. A. Mokrushina
Publikováno v:
Biochemistry. Biokhimiia. 85(11)
The discovery of antibiotics was one of the fundamental stages in the development of humanity, leading to a dramatic increase in the life expectancy of millions of people all over the world. The uncontrolled use of antibiotics resulted in the selecti
Autor:
S V Panteleev, Ivan V. Smirnov, O. N. Khokhlova, V. A. Palikov, Stanislav S. Terekhov, V. A. Kazakov, Yu. A. Palikova, O. G. Shamborant, Igor A. Dyachenko, Yu. A. Mokrushina, Alexander G. Gabibov, V. D. Knorre
Publikováno v:
Acta Naturae
The development of antidotes to organophosphate poisons is an important aspect of modern pharmacology. Recombinant acetylcholinesterase and butyrylcholinesterase are effective DNA-encoded acceptors of organophosphate poisons and, in particular, pesti
Autor:
Yu. A. Mokrushina, S. O. Pipiya, A. V. Stepanova, O. G. Shamborant, V. D. Knorre, I. V. Smirnov, A. G. Gabibov, I. I. Vorobiev
Publikováno v:
Molecular Biology. 51:830-839
Autor:
Yu. A. Mokrushina, V. D. Knorre, Alexander G. Gabibov, A. V. Stepanova, Sofiya O. Pipiya, Ivan I. Vorobiev, Ivan V. Smirnov, O. G. Shamborant
Publikováno v:
Молекулярная биология. :958-968
Catalytic antibodies are a promising model for creating highly specific biocatalysts with predetermined activity. However, in order to realize the directed change or improve their properties, it is necessary to understand the basics of catalysis and
Autor:
Yu. A. Mokrushina, O. G. Shamborant, T K Aliev, E. N. Khurs, V. D. Knorre, R. Yu. Popov, Alexander G. Gabibov, Ivan V. Smirnov, T. V. Bobik
Publikováno v:
Bulletin of experimental biology and medicine. 167(3)
The development and manufacturing of serum-free culture media allowing reducing the costs of preparations and standardizing the biotechnological process are important trends in biotechnology. Substitution of protein compounds in the serum-free media
Publikováno v:
Bulletin of Experimental Biology and Medicine. 161:83-87
We propose a new method of obtaining of stable Fab-fragments of antibodies in Pichia pastoris expression system. Recently, we obtained Fab-fragments of antibodies neutralizing organophosphorus toxins. However, high yield of the target products was no
Autor:
S. S. Terekhov, T. V. Bobik, Yu. A. Mokrushina, A. V. Stepanov, N. M. Aleksandrova, I. V. Smirnov, A. A. Belogurov, N. A. Ponomarenko, A. G. Gabibov
Publikováno v:
Прикладная биохимия и микробиология. 52:184-192
Autor:
Yu A, Mokrushina, S O, Pipiya, A V, Stepanova, O G, Shamborant, V D, Knorre, I V, Smirnov, A G, Gabibov, I I, Vorobiev
Publikováno v:
Molekuliarnaia biologiia. 51(6)
Catalytic antibodies are a promising model for creating highly specific biocatalysts with predetermined activity. However, in order to realize the directed change or improve their properties, it is necessary to understand the basics of catalysis and