Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yu. A. Lopatnikova"'
Autor:
Yu. A. Lopatnikova, Yu. V. Zhukova, A. A. Alshevskaya, I. A. Obleukhova, F. D. Kireev, I. A. Belomestnova, S. V. Sennikov
Publikováno v:
Медицинская иммунология, Vol 25, Iss 3, Pp 459-464 (2023)
TNFa is a pro-inflammatory cytokine that is signaled through type 1 (TNFR1) and type 2 (TNFR2) receptors. TNFR1 normally mediates apoptosis, cell survival, and cytokine secretion, while TNFR2 selectively mediates cell survival and cytokine secretion.
Externí odkaz:
https://doaj.org/article/90c612f004394c449523be0cc6a339af
Autor:
Yu. V. Zhukova, A. A. Alshevskaya, F. D. Kireev, O. A. Chumasova, N. S. Shkaruba, A. E. Sizikov, Yu. A. Lopatnikova, D. V. Demina, A. V. Karaulov, A. N. Silkov, S. V. Sennikov
Publikováno v:
Медицинская иммунология, Vol 23, Iss 4, Pp 903-908 (2021)
A pleiotropic cytokine TNFα is an important inflammatory mediator of a number of diseases; its biological functions are fulfilled through two different receptors, TNFR1 and TNFR2. Changes in the ratio between these types of receptors shifting the ba
Externí odkaz:
https://doaj.org/article/482fd1a256c14ef8b21598e321ea6907
Autor:
S. V. Sennikov, A. A. Alshevskaya, Yu. V. Zhukova, I. A. Belomestnova, A. V. Karaulov, Yu. A. Lopatnikova
Publikováno v:
Медицинская иммунология, Vol 21, Iss 3, Pp 379-396 (2019)
The present review article summarizes the latest world scientific data on the role of receptors for immune mediators in regulating biological effects on the cells. For the main classes of immune regulators (interleukins, interferons, growth factors a
Externí odkaz:
https://doaj.org/article/18bc7b422fa24f5ab96ba8bd5a96743e
Autor:
T. V. Tyrinova, S. V. Mishinov, O. Yu. Leplina, A. A. Alshevskaya, Yu. D. Kurochkina, E. A. Oleynik, А. V. Kalinovskiy, Yu. A. Lopatnikova, S. V. Chernov, V. V. Stupak, S. V. Sennikov, A. A. Ostanin, E. R. Chernykh
Publikováno v:
Медицинская иммунология, Vol 20, Iss 3, Pp 353-364 (2018)
Dendritic cells (DCs) of patients with high-grade brain glioma exhibit impaired expression of membrane TNFα associated with low DC cytotoxicity against TNF-R1-expressing tumor cell line HEp-2. To assess the significance of these findings, we investi
Externí odkaz:
https://doaj.org/article/55d82abeb5a845fca8999827edb477a9
Autor:
A. Z. Maksyutov, Yu. A. Lopatnikova, V. V. Kurilin, Yu. A. Shevchenko, Yu. N. Khantakova, E. V. Gavrilova, R. A. Maksyutov, A. G. Peregudov, S. A. Zaytsev, V. A. Kozlov, S. V. Sennikov
Publikováno v:
Медицинская иммунология, Vol 16, Iss 5, Pp 417-424 (2014)
This study describes a design of genetic constructs encoding either non-specific, or HLA-A *0201-specific polyepitopic immunogens containing antigenic determinants for HER2 protein. We have shown that transfection of mature dendritic cells by polyepi
Externí odkaz:
https://doaj.org/article/27bfad0017444550bbf58a5766869c9c
Autor:
D. D. Tsyrendorzhiev, S. V. Sennikov, I. A. Orlovskaya, I. P. Gileva, I. A. Ryazankin, L. B. Toporkova, V. V. Kurilin, Yu. A. Lopatnikova, A. A. Grydina, S. N. Schelkunov
Publikováno v:
Медицинская иммунология, Vol 15, Iss 6, Pp 513-524 (2014)
Abstract. This paper presents the results of the research on the effectiveness of recombinant TNF-binding protein of variola virus (VARV-CrmB) in a model of collagen-induced arthritis (CIA) in mice (CBAxC57Bl6) F1. The introduction of VARV-CrmB and p
Externí odkaz:
https://doaj.org/article/6bd0fc6fdfea43959facbd28c55ebf8b
Autor:
F. D. Kireev, O. A. Chumasova, N. S. Shkaruba, Yu. V. Zhukova, Yu. A. Lopatnikova, A. N. Silkov, Sergey Sennikov, A. A. Alshevskaya, Aleksander V. Karaulov, A. Sizikov, D. V. Demina
Publikováno v:
Medicinskaâ Immunologiâ, Vol 23, Iss 4, Pp 903-908 (2021)
A pleiotropic cytokine TNFα is an important inflammatory mediator of a number of diseases; its biological functions are fulfilled through two different receptors, TNFR1 and TNFR2. Changes in the ratio between these types of receptors shifting the ba
Publikováno v:
Bulletin of Experimental Biology and Medicine. 153:68-71
Associations of cytokine production by mononuclear cells and the TNF-α genetic polymorphism in positions -238, -308, -376, -857, -1031, and of IL-1β in positions -31 and +3954 were studied. The data on distribution of allele and genotype incidence