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Akademický článek

Fructose overconsumption impairs hepatic manganese homeostasis and ammonia disposal

Autor: Jian-Hui Shi, Yu-Xia Chen, Yingying Feng, Xiaohang Yang, Jie Lin, Ting Wang, Chun-Chun Wei, Xian-Hua Ma, Rui Yang, Dongmei Cao, Hai Zhang, Xiangyang Xie, Zhifang Xie, Weiping J. Zhang

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)

Abstract Arginase, a manganese (Mn)-dependent enzyme, is indispensable for urea generation and ammonia disposal in the liver. The potential role of fructose in Mn and ammonia metabolism is undefined. Here we demonstrate that fructose overconsumption

Externí odkaz: https://doaj.org/article/014ff36b029a4ce38946bd821c2f6fce

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Akademický článek

Roles of Psychosocial Factors on the Association Between Online Social Networking Use Intensity and Depressive Symptoms Among Adolescents: Prospective Cohort Study

Autor: Ji-Bin Li, Li-Fen Feng, Anise M S Wu, Jin-Chen Mai, Yu-Xia Chen, Phoenix K H Mo, Joseph T F Lau

Publikováno v: Journal of Medical Internet Research, Vol 23, Iss 9, p e21316 (2021)

BackgroundThe potential mechanisms underlying the association between online social networking use intensity and depressive symptoms are unclear and underresearched. ObjectiveWe aimed to investigate the potential roles of interpersonal psychosocial

Externí odkaz: https://doaj.org/article/9a513a8c8122450dafe9e6c6ba85ce31

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Akademický článek

Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20

Autor: Gan Liu, Luting Zhou, Hai Zhang, Rong Chen, Ye Zhang, Ling Li, Jun-Yu Lu, Hui Jiang, Dong Liu, Shasha Qi, Ying-Ming Jiang, Kai Yin, Zhifang Xie, Yuguang Shi, Yong Liu, Xuetao Cao, Yu-Xia Chen, Dajin Zou, Weiping J. Zhang

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

De novo lipogenesis is tightly controlled by hormonal and nutritional signals and plays an important role in energy homoeostasis. Here, Liu et al. show that zinc finger protein ZBTB20 regulates the expression of key glycolytic and lipogenic genes by

Externí odkaz: https://doaj.org/article/b81cc4076fdc4b64ab9d4bbb68641880

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Akademický článek

ZBTB20 is required for anterior pituitary development and lactotrope specification

Autor: Dongmei Cao, Xianhua Ma, Jiao Cai, Jing Luan, An-Jun Liu, Rui Yang, Yi Cao, Xiaotong Zhu, Hai Zhang, Yu-Xia Chen, Yuguang Shi, Guang-Xia Shi, Dajin Zou, Xuetao Cao, Michael J. Grusby, Zhifang Xie, Weiping J. Zhang

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)

The pituitary is a complex structure with the anterior lobe containing five specialized cell types secreting different hormones. Here Cao et al. unravel a role for ZBTB20 in pituitary development and specifically in lactrotrope specification.

Externí odkaz: https://doaj.org/article/7d92585d1fcf43e69c1f7145ec6e33f1

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Akademický článek

Involvement of small G protein RhoB in the regulation of proliferation, adhesion and migration by dexamethasone in osteoblastic cells.

Autor: Fei Diao, Kangyao Chen, Yan Wang, Yidong Li, Weidong Xu, Jian Lu, Yu-Xia Chen

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0174273 (2017)

Long-term exposure to therapeutic doses of glucocorticoids (GCs) results in bone remodeling, which frequently causes osteoporosis and fracture healing retardation because of the abnormality of osteoblastic proliferation and differentiation. The mecha

Externí odkaz: https://doaj.org/article/c8ca9a095fd84761b17290b289bbd8e0

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Akademický článek

Characterization of blaCTX-M Gene in One Klebsiella pneumoniae Isolate from Sick Chickens in China

Autor: Gong-zheng HU, Han HU, Bao-guang LIU, Li YUAN, Jian-hua LIU, Yu-shan PAN, Hua WU, Yu-xia CHEN

Publikováno v: Journal of Integrative Agriculture, Vol 11, Iss 10, Pp 1714-1720 (2012)

Two Klebsiella pneumoniae isolates (Kpc1 and Kpc2) were obtained from liver samples of seven dead chickens and identified with Vitek-32 automated identification system. Antimicrobial susceptibilities were determined by the microdilution broth method.

Externí odkaz: https://doaj.org/article/cf7dcda6ba2b4627b234bb2e82eac162

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Akademický článek

The long⁃term follow⁃up report of an 18q⁃syndrome patient for 4 years and literature review

Autor: Yu⁃xia CHEN, Nong XIAO

Publikováno v: Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 12, Iss 5, Pp 618-621 (2012)

DOI：10.3969/j.issn.1672⁃6731.2012.05.022

Externí odkaz: https://doaj.org/article/776638ece9ac46f7afe51138b53747fd

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