Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yu-ting Qin"'
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 214-231 (2022)
Background: Several studies scatteredly identified the myelodysplastic syndromes’ transcriptomic profiles (MDS). However, the exploration of transcriptional signatures, key signalling pathways, and their association with prognosis and diagnosis in
Externí odkaz:
https://doaj.org/article/387da276ffba438f913f3053b0e44ad9
Autor:
Niluopaer Tuerxun, Jie Wang, Yu-ting Qin, Fang Zhao, Huan Wang, Jian-hua Qu, Md. Nazim Uddin, Jian-ping Hao
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 506-517 (2022)
The deregulation of microRNAs (miRNAs) and genes in the bone marrow microenvironment have been involved with the pathogenesis of multiple myeloma (MM). However, the exploration of miRNA-mRNA regulatory networks in MM remains lacking. We used GSE12536
Externí odkaz:
https://doaj.org/article/84925285fcce43038e5a5f75a4a286ce
Autor:
Huanhuan Li, Tingting Long, Jun Tan, Bochu Wang, Wei Dong, Mingxin Xiong, Chengjiang Du, Jianxia Zhan, Qin Kuang, Deshuai Lou, Chenxu Ge, Ping Huang, Qiang Li, Minxuan Xu, Qiufeng Yang, Jing Feng, Linfeng Hu, Xuepeng Teng, Yan Sun, Liancai Zhu, Yekuan Wu, Xianling Dai, Yu-Ting Qin
Publikováno v:
Hepatology. 73:1346-1364
BACKGROUND AND AIMS Nonalcoholic fatty liver disease (NAFLD) has been widely recognized as a precursor to metabolic complications. Elevated inflammation levels are predictive of NAFLD-associated metabolic disorder. Inactive rhomboid-like protein 2 (i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79514e027c6c206b820fd9b97f4c23ad
https://doi.org/10.1002/hep.31436
https://doi.org/10.1002/hep.31436
Autor:
Niluopaer Tuerxun, Liu Yao, Jian-Ping Hao, Yu-Ting Qin, Fang Zhao, Ming Jiang, Jie Wang, Huan Wang
Publikováno v:
Hematology. 26:518-528
OBJECTIVE Hypomethylating agents (HMAs) have been reported to target the Sonic Hedgehog (Shh) signaling pathway in myelodysplastic syndrome (MDS). However, the synergistic inhibitory effect of Smo inhibitor jervine and its combination with decitabine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b780d641de8c8ab083c80e133329a3e4
https://doi.org/10.1080/16078454.2021.1950897
https://doi.org/10.1080/16078454.2021.1950897
Autor:
Bochu Wang, Chenxu Ge, Linfeng Hu, Yekuan Wu, Minxuan Xu, Yu-Ting Qin, Jun Tan, Jing Feng, Deshuai Lou, Qiang Li
Publikováno v:
Molecular Metabolism, Vol 34, Iss, Pp 112-123 (2020)
Molecular Metabolism
Molecular Metabolism
Objective Chronic inflammation of adipose tissues contributes to obesity-triggered insulin resistance. Unfortunately, the potential molecular mechanisms regarding obesity-associated systemic inflammation and metabolic disorder remain complicated. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f211fd00c274721a48398a74065437
http://www.sciencedirect.com/science/article/pii/S2212877820300107
http://www.sciencedirect.com/science/article/pii/S2212877820300107
Autor:
Fang, Zhao, Kai-Li, Wang, Yu-Ting, Qin, Tuerxun, Nilupar, Abulizi, Patiguli, Ming, Jiang, Jian-Ping, Hao
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 29(6)
To investigate the characteristics of gene mutations in patients with myelodysplastic syndromes (MDS) and its prognostic significance.High-throughput sequencing was used to detect 34 blood tumor-related genes in 210 patients with MDS, and the relatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0665bcd47e9cc2f31add4c1ff5c2b627
https://pubmed.ncbi.nlm.nih.gov/34893124
https://pubmed.ncbi.nlm.nih.gov/34893124
Autor:
Huanhuan Li, Mingxing Xiong, Tingting Long, Qin Kuang, Yu-Ting Qin, Jianxia Zhan, Xu Minxuan, Tingting Tang, Ge Chenxu, Tan Jun, Xianling Dai, Yan Sun
Publikováno v:
Journal of Functional Foods, Vol 53, Iss, Pp 7-21 (2019)
Excess fat-rich diet ingestion predisposes the liver to non-alcoholic fatty liver disease (NAFLD), but the mechanism is complicated. Fisetin (Fn) as a natural flavonoid with many bio-activities was determined in a number of diseases models. TACE (tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2361fd464f6f56a6dfbac5c897c2afd8
https://doi.org/10.1016/j.jff.2018.12.007
https://doi.org/10.1016/j.jff.2018.12.007
Autor:
Yu-Ting, Qin, Liu, Yao, Zhen, Yin, Shuang, Chen, Huan, Wang, Wen-Xia, Fan, Ming, Jiang, Jian-Ping, Hao
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 28(5)
To study the expression of Shh singaling related gene, including Shh, Ptch1, Smo and Gli1 in bone marrow CD34The count of CD34The expression levels of Shh, Smo and Gli1 of patients in MDS and AML-MRC group were significantly higher than those in cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6b6f1355aa8c3fe796a6c600b65f75c
https://pubmed.ncbi.nlm.nih.gov/33067966
https://pubmed.ncbi.nlm.nih.gov/33067966
Autor:
Yu-Ting, Qin, Liu, Yao, Zhen, Yin, Huan, Wang, Shuang, Chen, Tuerxun, Nilupar, Yasen, Halida, Yang, Liu, Abulizi, Patiguli, Ming, Jiang, Jian-Ping, Hao
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 28(4)
To study the effect of SMO inhibitor (Jervine) on proliferation, apoptosis and cell cycle of MDS cell line MUTZ-1, and its mechanism.The effect of different concentrations Jervine on proliferation of MUTZ-1 cells was detected by CCK-8 method. Apoptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf2ca750938e82ba15af2898510d43a2
https://pubmed.ncbi.nlm.nih.gov/32798415
https://pubmed.ncbi.nlm.nih.gov/32798415
Publikováno v:
Gene. 754
Objective This study aims to investigate the roles of Sonic hedgehog (Shh) signaling pathway in the occurrence and progression of Myelodysplastic Syndrome (MDS) and further evaluate using jervine as therapeutic strategy for MDS by inhibiting Shh path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b6527d62458380cb0adb8f66daaced
https://pubmed.ncbi.nlm.nih.gov/32526259
https://pubmed.ncbi.nlm.nih.gov/32526259