Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Yu-ichiro Koma"'
Autor:
Shuichi Tsukamoto, Takayuki Kodama, Mari Nishio, Manabu Shigeoka, Tomoo Itoh, Hiroshi Yokozaki, Yu-ichiro Koma
Publikováno v:
Cells, Vol 13, Iss 20, p 1682 (2024)
(Background) Cancer-associated fibroblasts (CAFs) are major cancer stromal components. CAFs have diverse functions and cell origins. Podoplanin (PDPN), a lymphatic vessel marker, is also a CAF marker in certain cancers. On daily diagnosis of early co
Externí odkaz:
https://doaj.org/article/e7bea0ecd0ce4360ab1bb2ce376bc195
Autor:
Takashi Nakanishi, Yu-ichiro Koma, Shoji Miyako, Rikuya Torigoe, Hiroki Yokoo, Masaki Omori, Keitaro Yamanaka, Nobuaki Ishihara, Shuichi Tsukamoto, Takayuki Kodama, Mari Nishio, Manabu Shigeoka, Hiroshi Yokozaki, Yoshihiro Kakeji
Publikováno v:
Cells, Vol 13, Iss 20, p 1733 (2024)
Cancer-associated fibroblasts (CAFs) are a key component of the tumor microenvironment and significantly contribute to the progression of various cancers, including esophageal squamous cell carcinoma (ESCC). Our previous study established a direct co
Externí odkaz:
https://doaj.org/article/e88aac8cdec644a4ad84ca048592f162
Autor:
Jun‐ichi Noiri, Yu Taniguchi, Yu Izawa, Nobuyuki Saga, Kaori Kusakabe, Yu‐ichiro Koma, Ken‐ichi Hirata
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare and critical malignancy‐related disease characterized by acute progressive pulmonary hypertension (PH). In most cases of PTTM, the cancer can be diagnosed in advance. Identificati
Externí odkaz:
https://doaj.org/article/ff97113a28fe40bd900fb19cdc15754c
Autor:
Yasuyuki Saito, Rie Iida-Norita, Tania Afroj, Alaa Refaat, Daisuke Hazama, Satomi Komori, Shinya Ohata, Tomoko Takai, Okechi S. Oduori, Takenori Kotani, Yohei Funakoshi, Yu-Ichiro Koma, Yoji Murata, Kimikazu Yakushijin, Hiroshi Matsuoka, Hironobu Minami, Hiroshi Yokozaki, Markus G. Manz, Takashi Matozaki
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tumor-associated macrophages (TAMs) are abundant in the tumor microenvironment and are considered potential targets for cancer immunotherapy. To examine the antitumor effects of agents targeting human TAMs in vivo, we here established preclinical tum
Externí odkaz:
https://doaj.org/article/784d3137dd2e455384e08104a9ce3615
Autor:
Yuki Azumi, Yu-ichiro Koma, Shuichi Tsukamoto, Yu Kitamura, Nobuaki Ishihara, Keitaro Yamanaka, Takashi Nakanishi, Shoji Miyako, Satoshi Urakami, Kohei Tanigawa, Takayuki Kodama, Mari Nishio, Manabu Shigeoka, Yoshihiro Kakeji, Hiroshi Yokozaki
Publikováno v:
Cells, Vol 12, Iss 22, p 2603 (2023)
Tumor-associated macrophages (TAMs), one of the major components of the tumor microenvironment, contribute to the progression of esophageal squamous cell carcinoma (ESCC). We previously established a direct co-culture system of human ESCC cells and m
Externí odkaz:
https://doaj.org/article/f9182f441fce484cbc97822d1d7798b3
Publikováno v:
Diagnostics, Vol 13, Iss 17, p 2857 (2023)
Hepatic inflammatory pseudotumors (IPTs) are defined as benign, non-malignant, non-metastasizing tumors characterized by the presence of myofibroblastic spindle cells, hetorogenous populations of inflammatory cells, particularly plasma cells, lymphoc
Externí odkaz:
https://doaj.org/article/ad67c9cf3a2c4756bd68e36cc61218c9
Autor:
Shoji Miyako, Takeru Matsuda, Yu-ichiro Koma, Takahiro Koide, Ryuichiro Sawada, Hiroshi Hasegawa, Kimihiro Yamashita, Hitoshi Harada, Naoki Urakawa, Hironobu Goto, Shingo Kanaji, Taro Oshikiri, Yoshihiro Kakeji
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 174 (2023)
Although a therapeutic response to neoadjuvant chemoradiotherapy (NACRT) is important to improve oncological outcomes after surgery in patients with locally advanced rectal cancer, there is no reliable predictor for this. The Wnt/β-catenin signal is
Externí odkaz:
https://doaj.org/article/a6ec3c7ea22c4a288638eb13b64a34fc
Publikováno v:
Clinical and Experimental Dental Research, Vol 5, Iss 6, Pp 627-637 (2019)
Abstract Objective Accumulating evidence suggests that macrophages are involved in the immunoediting of oral squamous cell carcinoma but the role of macrophages in oral carcinogenesis is unclear. We aimed to clarify the role of macrophages in oral le
Externí odkaz:
https://doaj.org/article/16e8645123dd451bb1d582614d4a3f96
Autor:
Manabu Shigeoka, Yu-ichiro Koma, Takayuki Kodama, Mari Nishio, Masaya Akashi, Hiroshi Yokozaki
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundCD163-positive macrophages contribute to the aggressiveness of oral squamous cell carcinoma. We showed in a previous report that CD163-positive macrophages infiltrated not only to the cancer nest but also to its surrounding epithelium, depe
Externí odkaz:
https://doaj.org/article/2bf8c3da899f415fa34b1236525b3cb6
Publikováno v:
Diagnostics, Vol 10, Iss 9, p 624 (2020)
Oral lichenoid conditions (OLC), including oral lichen planus (OLP), oral lichenoid lesions and oral lichenoid dysplasia, differ in pathogenesis and biological malignancy. However, distinguishing them based on clinical or histological features is dif
Externí odkaz:
https://doaj.org/article/7f78d976e8844680becd683124f6f0ef