Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Yu-ichi Kamikubo"'
Autor:
Yu-ichi Kamikubo
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 32:42-45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9711a03a8f7b8a2c0403e3245e92dcd
https://doi.org/10.2491/jjsth.32.42
https://doi.org/10.2491/jjsth.32.42
Autor:
Yu-ichi Kamikubo, Rashmi Sood, Yosuke Morodomi, Stefano Forli, Jennifer N. Orje, Robert R. Montgomery, Zaverio M. Ruggeri, Sachiko Kanaji, Sandra L. Haberichter, Alessandro Zarpellon, Yunfeng Chen, Jerome Eberhardt, Taisuke Kanaji, Scot A. Fahs
Publikováno v:
Blood Advances. 2:2522-2532
The interaction of platelet glycoprotein Ibα (GPIbα) with von Willebrand factor (VWF) initiates hemostasis after vascular injury and also contributes to pathological thrombosis. GPIbα binding to the VWF A1 domain (VWFA1) is a target for antithromb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41e100404a3c4ed875f6ca1fb010a00
https://doi.org/10.1182/bloodadvances.2018023507
https://doi.org/10.1182/bloodadvances.2018023507
Autor:
Wolfram Ruf, Sriram Krishnaswamy, Jennifer N. Orje, Andrew J. Gale, Andrea S. Rothmeier, Yu-ichi Kamikubo, Lars Christian Petersen, Zaverio M. Ruggeri, Antonella Zampolli, G. Loredana Mendolicchio, Patrizia Marchese, Henrik Østergaard, Andras Gruber
Publikováno v:
Blood. 130:1661-1670
Safe and effective antithrombotic therapy requires understanding of mechanisms that contribute to pathological thrombosis but have a lesser impact on hemostasis. We found that the extrinsic tissue factor (TF) coagulation initiation complex can select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6cd00ccf870ac8a8747350da348a95
https://doi.org/10.1182/blood-2017-02-767079
https://doi.org/10.1182/blood-2017-02-767079
Autor:
Joseph M. Cantor, Andrea S. Rothmeier, Mark H. Ginsberg, Florian Langer, Florence Schaffner, Wolfram Ruf, Zaverio M. Ruggeri, Patrizia Marchese, Yu-ichi Kamikubo
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology, vol 37, iss 7
Objective— Coagulation initiation by tissue factor (TF) is regulated by cellular inhibitors, cell surface availability of procoagulant phosphatidylserine, and thiol-disulfide exchange. How these mechanisms contribute to keeping TF in a noncoagulant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ec0581ab94d1654bc07fdc9d5b1ebc
https://europepmc.org/articles/PMC5501484/
https://europepmc.org/articles/PMC5501484/
Publikováno v:
Biochemical Journal. 410:595-604
The extracellular domain of the human leptin receptor (Ob-R) contains 20 potential N-glycosylation sites whose role in leptin binding remains to be elucidated. We found that a mammalian cell-expressed sOb-R (soluble Ob-R) fragment (residues 22-839 of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddb56e40f423a0ec7a7da9f011f82db
https://doi.org/10.1042/bj20071137
https://doi.org/10.1042/bj20071137
Autor:
Peter A. Andreasen, Yu-ichi Kamikubo, Andras Gruber, Andrey A. Komissarov, Paul Declerck, Aiwu Zhou
Publikováno v:
Thrombosis Research. 122:397-404
Background Activated protein C (APC) reduces mortality in severe sepsis. Protecting APC in the circulatory system from inactivation by serine protease inhibitors (serpins) could improve its therapeutic efficiency. Significantly elevated levels of a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1fa6125c196481551713f45f093d58
https://doi.org/10.1016/j.thromres.2007.10.012
https://doi.org/10.1016/j.thromres.2007.10.012
Autor:
De Guzman R, Stanisław Ołdziej, A. Jagielska, Yu-ichi Kamikubo, Harold A. Scheraga, Jaap G. Neels, David J. Loskutoff, Michael J. Churchill, Gerard Kroon, Scott A. Curriden, H.J. Dyson, Philip E. Dawson
Publikováno v:
ResearcherID
The N-terminal cysteine-rich somatomedin B (SMB) domain (residues 1-44) of the human glycoprotein vitronectin contains the high-affinity binding sites for plasminogen activator inhibitor-1 (PAI-1) and the urokinase receptor (uPAR). We previously show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36c3b1bcf7217ee995e8f186c9c604a
https://doi.org/10.1021/bi049647c
https://doi.org/10.1021/bi049647c
Publikováno v:
Journal of Biological Chemistry. 277:27109-27119
The NH(2)-terminal somatomedin B (SMB) domain (residues 1-44) of human vitronectin contains eight Cys residues organized into four disulfide bonds and is required for the binding of type 1 plasminogen activator inhibitor (PAI-1). In the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba020a6755d6386546d1a2414a96685
https://doi.org/10.1074/jbc.m200354200
https://doi.org/10.1074/jbc.m200354200
Autor:
Hiroshi Nonogi, Kousuke Kumeda, Akito Kawaguchi, Hisao Kato, Akira Yamamoto, Masakazu Yamagishi, Kunio Miyatake, Yu-ichi Kamikubo, Yuji Miyao, Motoo Tsushima, Teruo Noguchi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 20:251-258
Abstract —To elucidate the distribution and clinical implications of tissue factor pathway inhibitor (TFPI) concentrations, we measured TFPI levels consisting of preheparin free, lipoprotein-bound (Lp-bound), and endothelial cell–anchor pools in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c26365c10e80ebfb82bc6be414c8a1b
https://doi.org/10.1161/01.atv.20.1.251
https://doi.org/10.1161/01.atv.20.1.251
Publikováno v:
Thrombosis and Haemostasis. 83:60-64
SummaryWe recently observed a patient with acquired inhibitor-induced F.VII deficiency whose plasma level of F.VII was < 1.0%. However, the biochemical nature of the inhibitor has not yet been clarified. In the present study, we purified the F.VII in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2be88a171623108281edc291760492
https://doi.org/10.1055/s-0037-1613758
https://doi.org/10.1055/s-0037-1613758