Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yu-hua Ran"'
Autor:
Ting-Ting Zhang, Rui Xue, Shi-Yong Fan, Qiong-Yin Fan, Lei An, Juan Li, Lei Zhu, Yu-Hua Ran, Li-Ming Zhang, Bo-Hua Zhong, Yun-Feng Li, Cai-Ying Ye, You-Zhi Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background Diabetic neuropathic pain (DNP) is a common and distressing complication in patients with diabetes, and the underlying mechanism remains unclear. Tricyclic antidepressants (TCAs) and serotonin and norepinephrine reuptake inhibitor
Externí odkaz:
https://doaj.org/article/390fc61dea9e4a97a7ad99cd4387098f
Autor:
Zeng-liang Jin, Xiao-Fei Chen, Yu-hua Ran, Xiao-rong Li, Jie Xiong, Yuan-yuan Zheng, Na-na Gao, Yun-Feng Li
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Selective serotonin reuptake inhibitors (SSRIs) bind 5-HT transporters, leading to the accumulation of 5-HT and amelioration of depression. Although different mouse strains show varying sensitivity to SSRIs in mouse models of depression, the
Externí odkaz:
https://doaj.org/article/78bdd53ea6f84db08c81c21dfa765df5
Autor:
Chao Shang, Yun-Feng Li, Jian-Min Zhang, Li-Ming Zhang, Zhen-Chun Ding, You-Zhi Zhang, Rui Xue, Ying Guo, Ru-Meng Yao, Yu-Hua Ran, Huai-Shan Wang, Li-Jun Sun
Publikováno v:
Journal of Psychopharmacology. 34:441-451
Background: Fast-acting and cognitive-enhancing antidepressants are desperately needed. Activation of translocator protein (18 kDa, TSPO) is a novel strategy for developing potential antidepressants, but there are no data available on the onset time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da2eeac342cc54a2140663593ad4c3e
https://doi.org/10.1177/0269881119896304
https://doi.org/10.1177/0269881119896304
The role of the excitation:inhibition functional balance in the mPFC in the onset of antidepressants
Autor:
Jin Yuan, Ze-Han Li, Li-Ming Zhang, Jun-Qi Yao, Yun-Hui Wang, Yun-Feng Li, Wen-Gang Liu, Yong-Yu Yin, Yu-Hua Ran
Publikováno v:
Neuropharmacology. 191
Currently available antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), generally require weeks to months to produce a therapeutic response, but the mechanism of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36469d6a4bbbb717ad6ec29dfb1c52b2
https://pubmed.ncbi.nlm.nih.gov/33945826
https://pubmed.ncbi.nlm.nih.gov/33945826
Autor:
Yu-Hua Ran, Xin-Xin Fang, Chang Liu, Yan-Qin Liu, Jun-Qi Yao, Yong-Yu Yin, Yun-Feng Li, Zeng-liang Jin, Li-Ming Zhang
Publikováno v:
Neuropharmacology. 178
Anxiety disorders are the most prevalent group of mental disorders globally, leading to considerable losses in health, functioning and increase of medical costs. Till now, the search for novel pharmacological treatments is driven by the growing medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e780debcf88576ff5510ed9a51c215
https://pubmed.ncbi.nlm.nih.gov/32693005
https://pubmed.ncbi.nlm.nih.gov/32693005
Autor:
Nan Zhao, Zeng-liang Jin, Yun-Feng Li, You-Zhi Zhang, Xiao-fei Chen, Ying Gong, Li-Ming Zhang, Yu-Hua Ran, Xiao-Yun Wang
Publikováno v:
Neuropharmacology. 138:1-9
Most current antidepressants are lacking a pro-cognition effect or even impair cognition as a side effect, and there are few effective psychopharmacological options that improve cognitive dysfunction in depression. Our previous studies revealed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a85e71cd51f9e09ac8aa22dcc6d25f
https://doi.org/10.1016/j.neuropharm.2018.05.027
https://doi.org/10.1016/j.neuropharm.2018.05.027
Publikováno v:
Acta Pharmacologica Sinica. 39:12-23
YL-0919 has been identified as a novel dual 5-HT1A partial agonist and serotonin reuptake inhibitor. In the current study, we demonstrated that YL-0919 produced prominent antidepressant-like and anxiolytic-like effects in a chronic unpredictable stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::667d2eaae8ccdd065dfa74fcc85013ad
https://doi.org/10.1038/aps.2017.83
https://doi.org/10.1038/aps.2017.83
Autor:
Yun-Feng Li, Jie Xiong, Xiaorong Li, Nana Gao, Zeng-liang Jin, Yu-Hua Ran, Yuanyuan Zheng, Xiao-Fei Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Selective serotonin reuptake inhibitors (SSRIs) bind 5-HT transporters, leading to the accumulation of 5-HT and amelioration of depression. Although different mouse strains show varying sensitivity to SSRIs in mouse models of depression, the underlyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfe2c408c0191d6706ab30bbe2c24fe
https://doaj.org/article/78bdd53ea6f84db08c81c21dfa765df5
https://doaj.org/article/78bdd53ea6f84db08c81c21dfa765df5
Autor:
Xiao-Xu Hu, Ri-Fang Yang, You-Zhi Zhang, Yun-Feng Li, Nan Zhao, Yu-Lu Wang, Li-Ming Zhang, Yu-Hua Ran, Xiao-Yun Wang, Yan-Qin Liu
Publikováno v:
British Journal of Pharmacology. 174:769-780
The purpose of the present study was to investigate the pharmacology of hypidone hydrochloride (YL-0919), a novel selective serotonin reuptake inhibitor (SSRI) and 5-hydroxytryptamine (5-HT)1A receptor agonist with high affinity for serotonin transpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c649a6051f523e2e714d84c2a8dcd47
https://doi.org/10.1111/bph.13675
https://doi.org/10.1111/bph.13675
Autor:
Xin-Xin Fang, Li-Jun Sun, Jun-Qi Yao, Chao Shang, Li-Ming Zhang, Yun-Feng Li, Yu-Hua Ran, Xiang-Yun Jiang, Zhen-Chun Ding, Heng-Lin Wang, Ying Guo
Publikováno v:
Behavioural Brain Research. 379:112320
There is a serious need for fast-acting drugs to treat post-traumatic stress disorder (PTSD). Our previous studies revealed that YL-IPA08, a novel small-molecule TSPO agonist, exerted significant anti-PTSD effects in various animal models. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199f4b171dbadfcd2a7dba5f52f6570d
https://doi.org/10.1016/j.bbr.2019.112320
https://doi.org/10.1016/j.bbr.2019.112320