Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Yu-he Yuan"'
Autor:
Yaping Zheng, Pei Li, Jie Shen, Kailin Yang, Xinyan Wu, Yue Wang, Yu-he Yuan, Peigen Xiao, Chunnian He
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
IntroductionPaeonia ostii T. Hong & J.X. Zhang (s.s.) (Chinese name, Fengdan) is a widely cultivated food-medicine plant in China, in which root bark, seed kernels, and flowers are utilized for their medicinal and edible values. However, other parts
Externí odkaz:
https://doaj.org/article/6cc141768e3c4035af9f4e4760849a2f
Publikováno v:
Molecules, Vol 27, Iss 21, p 7414 (2022)
Accumulating evidence has shown that Parkinson’s disease (PD) is a systemic disease other than a mere central nervous system (CNS) disorder. One of the most important peripheral symptoms is gastrointestinal dysfunction. The enteric nervous system (
Externí odkaz:
https://doaj.org/article/8c1e15b8634e4627b260c68ad9837bd7
Publikováno v:
Molecules, Vol 23, Iss 11, p 2839 (2018)
Genetic studies have revealed that rare mutations and multiplications of the gene locus in α-synuclein (α-syn) are implicated in the pathogenesis of Parkinson’s disease (PD). However, the pathological effects of α-syn are still obscure. The neur
Externí odkaz:
https://doaj.org/article/19153a004f57497aa87dea5d7eb73446
Autor:
Lian-Kun Song, Kai-Li Ma, Yu-He Yuan, Zheng Mu, Xiu-Yun Song, Fei Niu, Ning Han, Nai-Hong Chen
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131281 (2015)
Mutations, duplication and triplication of α-synuclein genes are linked to familial Parkinson's disease (PD), and aggregation of α-synuclein (α-syn) in Lewy bodies (LB) is involved in the pathogenesis of the disease. The targeted overexpression of
Externí odkaz:
https://doaj.org/article/8830b2b388a04668a2a9f8ef43b3ab0e
Publikováno v:
F1000Research, Vol 3 (2014)
The accumulation of misfolded a-synuclein is mechanistically linked to neurodegeneration in Parkinson’s disease (PD) and other alpha-synucleinopathies. However, how alpha-synuclein causes neurodegeneration is unresolved. Several studies have suppor
Externí odkaz:
https://doaj.org/article/73aac9f23d2a4ea892ab6a333827b5dc
Publikováno v:
Neurochemical Research. 47:3627-3634
Parkinson's disease (PD) is a chronic neurodegenerative disease mainly characterized by movement disorders and other non-motor symptoms, including the loss of dopaminergic neurons in the substantia nigra parts. Abnormal α-synuclein aggregation in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c932133461a2b328605446c564bafb4
https://doi.org/10.1007/s11064-022-03586-0
https://doi.org/10.1007/s11064-022-03586-0
Publikováno v:
Acta Pharmacologica Sinica. 43:2253-2266
Neuroinflammation is closely related to the pathogenesis of neurodegenerative diseases. Activation of microglia, the resident immune cells in CNS, induces inflammatory responses, resulting in the release of neurotoxic molecules, which favors neuronal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0115339faf15f3eb8f10dcc4143e9cf
https://doi.org/10.1038/s41401-021-00853-8
https://doi.org/10.1038/s41401-021-00853-8
Autor:
Nai-Hong Chen, Si-Tong Feng, Zhi-Peng Li, Xiao-Le Wang, Yu-He Yuan, Ya-Ting Wang, Yi Zhang, Zhen-Zhen Wang
Publikováno v:
Cellular and Molecular Neurobiology. 42:1321-1339
Parkinson's disease (PD) is a severe neurodegenerative disorder caused by the progressive loss of dopaminergic neurons in the substantia nigra and affects millions of people. Currently, mitochondrial dysfunction is considered as a central role in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20344222ab833983ba7c72383df3539
https://doi.org/10.1007/s10571-021-01039-w
https://doi.org/10.1007/s10571-021-01039-w
Publikováno v:
Acta Pharmacol Sin
Huntington’s disease (HD) is one of main neurodegenerative diseases, characterized by striatal atrophy, involuntary movements, and motor incoordination. Ginsenoside Rg1 (Rg1), an active ingredient in ginseng, possesses a variety of neuroprotective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b5f01f43d018be064b6ad386e96335
https://doi.org/10.1038/s41401-020-00558-4
https://doi.org/10.1038/s41401-020-00558-4
Autor:
Min Zhang, Qing-Lan Guo, Yanan Wang, Yongchun Yang, Chengbo Xu, Yu-He Yuan, Xue Zhou, Nai-Hong Chen, Cheng-Gen Zhu, Jiangong Shi
Publikováno v:
Natural Products and Bioprospecting
Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 31-50 (2020)
Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 31-50 (2020)
From an aqueous extract of “tian ma” (the steamed and dried rhizomes of Gastrodia elata), ten new compounds gastrodibenzins A−D (1−4) and gastrotribenzins A−F (5−10), along with known analogues (11−20), having structure features couplin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfc24843c448fb959378bf08e7e1094
http://europepmc.org/articles/PMC7933327
http://europepmc.org/articles/PMC7933327