Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Yu-Zhi Fu"'
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract The newly emerging coronavirus SARS-CoV-2 causes severe lung disease and substantial mortality. How the virus evades host defense for efficient replication is not fully understood. In this report, we found that the SARS-CoV-2 nucleocapsid pr
Externí odkaz:
https://doaj.org/article/632c797bc210429ea21d9b702364a008
Publikováno v:
Cell Insight, Vol 1, Iss 2, Pp 100014- (2022)
After herpes simplex virus type 1 (HSV-1) infection, the cytosolic sensor cyclic GMP-AMP synthase (cGAS) recognizes DNA and catalyzes synthesis of the second messenger 2′3′-cGAMP. cGAMP binds to the ER-localized adaptor protein MITA (also known a
Externí odkaz:
https://doaj.org/article/fcb8742a208d4c82becae0bdf1e0a522
Autor:
Huan Lian, Jin Wei, Ru Zang, Wen Ye, Qing Yang, Xia-Nan Zhang, Yun-Da Chen, Yu-Zhi Fu, Ming-Ming Hu, Cao-Qi Lei, Wei-Wei Luo, Shu Li, Hong-Bing Shu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
cGAS is an important mediator of antiviral immune responses, but the regulation of its activity is unknown. Here, the authors identify a zinc finger protein, ZCCHC3, that enhances the binding of cGAS to dsDNA and is important for its activation follo
Externí odkaz:
https://doaj.org/article/787e1f46425144ed98d0dc92723cdac6
Autor:
Huan Lian, Jin Wei, Ru Zang, Wen Ye, Qing Yang, Xia-Nan Zhang, Yun-Da Chen, Yu-Zhi Fu, Ming-Ming Hu, Cao-Qi Lei, Wei-Wei Luo, Shu Li, Hong-Bing Shu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/6bbe448f6a6e4e3688bfcad46115a65d
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007691 (2019)
Cyclic GMP-AMP synthase (cGAS) senses viral DNA in the cytosol and then catalyzes synthesis of the second messenger cGAMP, which activates the ER-localized adaptor protein Mediator of IRF3 Activator (MITA) to initiate innate antiviral response. Human
Externí odkaz:
https://doaj.org/article/65ce37c2e1a147088143dc8d2dae55b8
Autor:
Chia-Man Chou, Le Tran Thanh Thi, Nguyen Thi Quynh Nhu, Su-Yu Liao, Yu-Zhi Fu, Le Vu Tuan Hung, Vincent K. S. Hsiao
Publikováno v:
Applied Sciences, Vol 10, Iss 14, p 5015 (2020)
We fabricated surface-enhanced Raman scattering (SERS) substrates using gold nanoparticle (AuNP)-decorated zinc oxide (ZnO) nanorods (NRs). Prior to decoration with AuNPs, ZnO NRs on the glass substrate fabricated using the sol–gel method could enh
Externí odkaz:
https://doaj.org/article/78227a5672d84c72b827eaf78df5b1f6
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Cell Discovery
Cell Discovery
The newly emerging coronavirus SARS-CoV-2 causes severe lung disease and substantial mortality. How the virus evades host defense for efficient replication is not fully understood. In this report, we found that the SARS-CoV-2 nucleocapsid protein (NP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80704054452c7801787e9b8789c5143
https://doaj.org/article/632c797bc210429ea21d9b702364a008
https://doaj.org/article/632c797bc210429ea21d9b702364a008
Autor:
Wei-Wei Luo, Huan Lian, Shu Li, Wen Ye, Yun-Da Chen, Cao-Qi Lei, Xia-Nan Zhang, Ming-Ming Hu, Yu-Zhi Fu, Hong-Bing Shu, Qing Yang, Jin Wei, Ru Zang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae7a79eaaaec8921a77c490a6ca6817
https://doi.org/10.1038/s41467-021-25397-7
https://doi.org/10.1038/s41467-021-25397-7
Publikováno v:
In Journal of Pain and Symptom Management June 2021 61(6):1297-1304
Publikováno v:
Cellular & Molecular Immunology
Cellular and Molecular Immunology
Cellular and Molecular Immunology
A novel SARS-related coronavirus (SARS-CoV-2) has recently emerged as a serious pathogen that causes high morbidity and substantial mortality. However, the mechanisms by which SARS-CoV-2 evades host immunity remain poorly understood. Here, we identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e9f18eea328fafb25037e87302a8d9