Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yu-Zhang Cao"'
Autor:
Lorraine M. Sordillo, Yu-Zhang Cao, Isis K. Mullarky, James Weaver, Matthew J. Sylte, Chris M. Corl
Publikováno v:
Prostaglandins & Other Lipid Mediators. 76:19-34
Oxidant stress plays an important role in the etiology of vascular diseases by increasing rates of endothelial cell apoptosis, but few data exist on the mechanisms involved. Using a unique model of oxidative stress based on selenium deficiency (-Se),
Publikováno v:
Biochemical and Biophysical Research Communications. 302:610-614
Oxidant stress, as a consequence of selenium (Se) deficiency, alters production of vasoactive compounds including platelet-activating factor (PAF). Recent studies report that enhanced PAF production during Se deficiency is a consequence of increased
Publikováno v:
Antioxidants & Redox Signaling. 3:1147-1152
Selenium (Se) deficiency has been reported to increase platelet-activating factor (PAF) production in human endothelial cells; however, the mechanism is unclear. This study demonstrated that tumor necrosis factor-alpha (TNF-alpha) stimulated Se-defic
Publikováno v:
Free Radical Biology and Medicine. 30:299-308
Selenium (Se) is an integral component of glutathione peroxidase and is able to detoxify peroxides that can affect arachidonic acid (AA) metabolism, thereby influencing eicosanoid biosynthesis. This study investigated the effects of oxidant stress, a
Publikováno v:
Free Radical Biology and Medicine. 28:381-389
Selenium (Se) is an integral part of the Se-dependent glutathione peroxidase (Se-GSH-Px) catalytic domain. By modulating the cellular levels of fatty acid hydroperoxides, Se-GSH-Px can influence key enzymes of arachidonic acid cascade, in this case c
Publikováno v:
Biochemical and Biophysical Research Communications. 229:630-634
Previously we reported that tumor-promoting phorbol esters stimulate phospholipase D (PLD) independent of protein kinase C (PKC) activation in bovine lymph node lymphocytes. (Cao et al., Biochem. Biophys. Res. Commun. 171, 955–962, 1990; 217, 908
Autor:
George Hildenbrandt, Andrea M. Mastro, Richard W. Scholz, C. Channa Reddy, Jane F. Maddox, Yu-Zhang Cao
Publikováno v:
The Journal of Nutrition. 122:2121-2127
We investigated the effect of altered selenium (Se) nutrition on arachidonic acid oxidation in immune cells. Experiments were conducted with peripheral blood lymphocytes obtained from dairy cattle fed diets either supplemented with or deficient in Se
Autor:
George Hildenbrandt, Yu Zhang Cao, C. Channa Reddy, Richard W. Scholz, Andrea M. Mastro, Jane F. Maddox
Publikováno v:
Biochemical and Biophysical Research Communications. 181:389-395
When peripheral blood lymphocytes were incubated with arachidonic acid in the presence of Ca++ ionophore (A23187), the cells from the selenium-deficient dairy cows produced significantly greater quantities of 12-hydroxyeicosatetraenoic acid (12-HETE)
Certain selenoproteins such as GPX-1 (glutathione peroxidase-1) and TrxR1 (thioredoxin reductase-1) possess important antioxidant defence functions in vascular endothelial cells. Reduced selenoprotein activity during dietary selenium (Se) deficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836f4d6bdfd7255bc820faaa652a2548
https://europepmc.org/articles/PMC1386018/
https://europepmc.org/articles/PMC1386018/
Publikováno v:
Prostaglandinsother lipid mediators. 70(1-2)
Previous reports have shown that selenium (Se) nutrition alters the lipoxygenase pathway and mitogenic responses in bovine lymphocytes. In order to further understand how Se may alter lymphocyte function, we examined the effects of Se nutrition on ar