Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Yu-Yuan Hsiao"'
Autor:
Kuan-Wei Huang, Jing-Wen Chen, Tzu-Yu Hua, Yu-Yu Chu, Tsai-Yuan Chiu, Jung-Yu Liu, Chun-I Tu, Kai-Cheng Hsu, Ya-Ting Kao, Jhih-Wei Chu, Yu-Yuan Hsiao
Publikováno v:
JACS Au, Vol 1, Iss 12, Pp 2315-2327 (2021)
Externí odkaz:
https://doaj.org/article/343f16f7f3374c72b7e2b55573f77491
Autor:
Tung-Chang Liu, Chun-Ting Lin, Kai-Cheng Chang, Kai-Wei Guo, Shuying Wang, Jhih-Wei Chu, Yu-Yuan Hsiao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The exonuclease Apurinic/apyrimidinic endonuclease 1 (APE1) is important for processing matched/mismatched terminus during DNA repair. Here the authors resolve the X-ray crystallography structures of APE1 with varied dsDNAs substrates to assay the nu
Externí odkaz:
https://doaj.org/article/ffb6ab14e7a9497fa2f390f15e2f2fc4
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3682-3691 (2021)
Mammalian apurinic/apyrimidinic (AP) endonuclease 1 (APE1) has versatile enzymatic functions, including redox, endonuclease, and exonuclease activities. APE1 is thus broadly associated with pathways in DNA repair, cancer cell growth, and drug resista
Externí odkaz:
https://doaj.org/article/362d09d77c0541c598a4972fc08e0477
Autor:
Kuan-Wei Huang, Tung-Chang Liu, Ruei-Yue Liang, Lee-Ya Chu, Hiu-Lo Cheng, Jhih-Wei Chu, Yu-Yuan Hsiao
Publikováno v:
PLoS Biology, Vol 16, Iss 5, p e2005653 (2018)
Three prime repair exonuclease 1 (TREX1) is an essential exonuclease in mammalian cells, and numerous in vivo and in vitro data evidenced its participation in immunity regulation and in genotoxicity remediation. In these very complicated cellular fun
Externí odkaz:
https://doaj.org/article/a2f79deab4214b6ca46936993c4384f4
Autor:
Jui-Chieh Yin, Chun-Hsien Fei, Yen-Chen Lo, Yu-Yuan Hsiao, Jyun-Cyuan Chang, Jay C Nix, Yuan-Yu Chang, Lee-Wei Yang, I-Hsiu Huang, Shuying Wang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Sortases function as cysteine transpeptidases that catalyze the covalent attachment of virulence-associated surface proteins into the cell wall peptidoglycan in Gram-positive bacteria. The substrate proteins targeted by sortase enzymes have a cell wa
Externí odkaz:
https://doaj.org/article/90455814d99144e1a8ba94ad5238dbc3
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001803 (2014)
DNA repair mechanisms are essential for preservation of genome integrity. However, it is not clear how DNA are selected and processed at broken ends by exonucleases during repair pathways. Here we show that the DnaQ-like exonuclease RNase T is critic
Externí odkaz:
https://doaj.org/article/bb08ec8882724f25930b0f0b784c269c
Autor:
Yu-Yuan Hsiao, 蕭瑜源
99
This study focuses on fully integrated radio frequency power amplifier by using TSMC 0.35μm BiCMOS process and 0.18μm BiCMOS process. In the first part, a fully integrated power amplifier by using power combining is studied first. The major
This study focuses on fully integrated radio frequency power amplifier by using TSMC 0.35μm BiCMOS process and 0.18μm BiCMOS process. In the first part, a fully integrated power amplifier by using power combining is studied first. The major
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/27851548594477410110
Autor:
Yu-Yuan Hsiao, 蕭羽媛
97
The total amount of motorcycles increased continuously as well as the emissions of pollution. Under the issue of global warming, the development of traffic and environmental policies should be further investigated into life science and techno
The total amount of motorcycles increased continuously as well as the emissions of pollution. Under the issue of global warming, the development of traffic and environmental policies should be further investigated into life science and techno
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/ssy56j
Autor:
Yu-Yuan Hsiao, 蕭裕元
87
The portal war has become an endless competition. Although it is important to add services and move in advance for a portal site, developing virtual community and reinforce customer loyalty with discretion are also powerful techniques. The "o
The portal war has become an endless competition. Although it is important to add services and move in advance for a portal site, developing virtual community and reinforce customer loyalty with discretion are also powerful techniques. The "o
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/57447595385629139520
Autor:
Kai-Cheng Hsu, Ya-Ting Kao, Jung-Yu Liu, Tsai-Yuan Chiu, Jhih-Wei Chu, Tzu-Yu Hua, Chun-I Tu, Jing-Wen Chen, Yu-Yuan Hsiao, Kuan-Wei Huang, Yu-Yu Chu
Publikováno v:
JACS Au, Vol 1, Iss 12, Pp 2315-2327 (2021)
JACS Au
JACS Au
For using targeted covalent inhibitors (TCIs) as anticancer and antiviral drugs, we establish that the model compounds PCMPS (p-chloromercuriphenyl sulfate) and PCMB (p-chloromercuribenzoate) are inhibitors of the DEDDh family of exonucleases. The un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0567140347d391c20d6124f8c22f37
https://doi.org/10.1021/jacsau.1c00420
https://doi.org/10.1021/jacsau.1c00420