Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yu-Yang Bi"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Non-small cell lung cancer (NSCLC) shows high drug resistance and leads to low survival due to the high level of mutated Tumor Protein p53 (TP53). Cisplatin is a first-line treatment option for NSCLC, and the p53 mutation is a major factor i
Externí odkaz:
https://doaj.org/article/1e69bc703a6140a1a2e5af77e5e2a22a
Autor:
Ming-Yuan, Yang, Yi-Jun, Lin, Meng-Meng, Han, Yu-Yang, Bi, Xing-Yue, He, Lei, Xing, Jee-Heon, Jeong, Tian-Jiao, Zhou, Hu-Lin, Jiang
Publikováno v:
Journal of Controlled Release. 351:623-637
Idiopathic pulmonary fibrosis (IPF) is a fibrotic interstitial lung disease in which collagen progressively deposits in the supporting framework of the lungs. The pathological collagen creates a recalcitrant barrier in mesenchyme for drug penetration
Autor:
Ming-Yuan Yang, Yi-Jun Lin, Meng-Meng Han, Yu-Yang Bi, Xing-Yue He, Lei Xing, Jee-Heon Jeong, Tian-Jiao Zhou, Hu-Lin Jiang
Publikováno v:
Journal of Controlled Release.
Autor:
Tian Lv, Chenxi Yang, Yu-Yang Bi, Jiang Hulin, Yuan Xu, Tao Sun, Jianbing Wu, Hao Wen, Zhangjian Huang, Rigang Cong, Jun Zhao, Yong Ling, Jianhua Wang, Yihua Zhang, Fei Li
Publikováno v:
Biomaterials Science. 9:1816-1825
Bond cleavage bioorthogonal chemistry has been widely employed to restore or activate proteins or prodrugs. Nitric oxide (NO), as a free radical molecule, has joined the clinical arena of cancer therapy, since high levels of NO could produce a cancer
Autor:
Chen-Xi Yang, Xin Chang, Yu-Yang Bi, Hu-Lin Jiang, Zhi-Qi Zhang, Lei Xing, Zhiqiang Yu, Tian-Jiao Zhou
Publikováno v:
Molecular Pharmaceutics. 17:1300-1309
Chemotherapy still accounts for a large proportion of the treatments of tumors, but the drug resistance and side effects caused by long-term chemotherapy should not be underestimated. In this work, the drug combination strategy has been widely develo