Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yu-Shuan Shiau"'
Autor:
Yu-Shuan Shiau, Pei-Ming Chen, Horng-Huei Liou, Po-Tsang Huang, Kuo-Long Lou, Michael James, Ming-Tao Lee, Meng-Hsuan Hsieh, Po-Huang Liang, Isaac Furay Yu, Tsang-Lang Lin, Stephen A. Holt
Publikováno v:
Langmuir. 34:9036-9046
Hanatoxin (HaTx) from spider venom works as an inhibitor of Kv2.1 channels, most likely by interacting with the voltage sensor (VS). However, the way in which this water-soluble peptide modifies the gating remains poorly understood as the VS is deepl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbcd27825a6c05c36913b391951d835
https://doi.org/10.1021/acs.langmuir.8b01076
https://doi.org/10.1021/acs.langmuir.8b01076
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 34(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d7e6c4000063b04da74e3fc7a935d2
https://pubmed.ncbi.nlm.nih.gov/28260386
https://pubmed.ncbi.nlm.nih.gov/28260386
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 33(11)
Membrane perturbation induced by cysteine-rich peptides is a crucial biological phenomenon but scarcely investigated, in particular with effective biophysical-chemical methodologies. Hanatoxin (HaTx), a 35-residue polypeptide from spider venom, works
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f8db1ce888b493da02b768e3133320
https://pubmed.ncbi.nlm.nih.gov/29299910
https://pubmed.ncbi.nlm.nih.gov/29299910
Autor:
Chan Lin, Kuo-Long Lou, Shu-Bin Horng, Po-Tsang Huang, Yi-Ching Hsueh, Ching-San Chen, Yu-Shuan Shiau
Publikováno v:
Journal of Molecular Recognition. 19:441-450
A variety of evolutionarily related defensin molecules is found in plants and animals. Plant gamma-thionins and scorpion neurotoxins, for instance, may be categorized in this functional group, although each class recognizes a distinct receptor bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e93787d0fdb1e19714c72f4468ee401
https://doi.org/10.1002/jmr.779
https://doi.org/10.1002/jmr.779
Autor:
Yuh-Yuan Shiau, Po-Tsang Huang, Kuo-Long Lou, Yu-Shuan Shiau, Horng-Huei Liou, Yen-Chywan Liaw
Publikováno v:
Journal of Molecular Recognition. 16:392-395
While S4 is known as the voltage sensor in voltage-gated potassium channels, the carboxyl terminus of S3 (S3C) is of particular interest concerning the site for gating modifier toxins like hanatoxin. The thus derived helical secondary structural arra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896c7bc568213800b0d9ab9858ebd6e6
https://doi.org/10.1002/jmr.614
https://doi.org/10.1002/jmr.614
Autor:
Hsiu-Chuan Chou, Yau-Wie Tsai, Po-Tsang Huang, Ting-Yu Chen, Yu-Shuan Shiau, Kuo-Long Lou, Robert J. French, Yuh-Yuan Shiau
Publikováno v:
Journal of Molecular Modeling. 7:20-25
Rundown is a generally encountered problem while recording KATP channel activity with inside-out patches. No assigned structural fragment related to this mechanism has yet been derived from any of the functional analyses performed. Therefore, based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6b77e155f3b11f7e8d3b1365e54f186
https://doi.org/10.1007/s008940100010
https://doi.org/10.1007/s008940100010
Autor:
Yuh-Yuan Shiau, Po-Tsang Huang, Yu-Shuan Shiau, Horng-Huei Liou, Yen-Chywan Liaw, Kuo-Long Lou
Publikováno v:
Chemical research in toxicology. 16(10)
Voltage-dependent potassium channel Kv2.1 is widely expressed in mammalian neurons and was suggested responsible for mediating the delayed rectifier (I(K)) currents. Further investigation of the central role of this channel requires the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c130f8ae98ef5212ad1f6ba4d5df1129
https://pubmed.ncbi.nlm.nih.gov/14565763
https://pubmed.ncbi.nlm.nih.gov/14565763
Publikováno v:
Journal of molecular recognition : JMR. 15(4)
The carboxyl terminus of S3 segment (S3C) in voltage-gated potassium channels was proposed to bear the binding site for gating modifier toxins like Hanatoxin and a helical secondary structural arrangement was suggested. Due to the lack of complete st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2302442ff6d876fd65750def0c728f3f
https://pubmed.ncbi.nlm.nih.gov/12382234
https://pubmed.ncbi.nlm.nih.gov/12382234
Publikováno v:
Journal of molecular modeling. 8(8)
The carboxyl terminus of the S3 segment (S3C) in voltage-gated potassium channels was suggested to be the binding site of gating modifier toxins like hanatoxin. It has also been proposed to have a helical secondary structural arrangement. The current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0af0fae9b1e8692c1bfd62f2975b42
https://pubmed.ncbi.nlm.nih.gov/12324802
https://pubmed.ncbi.nlm.nih.gov/12324802
Autor:
Yuh-Yuan Shiau, Pi-Jung Hsu, Yau-Wei Tsai, Hsiou-Chuan Chou, Lih-Jung Tseng, Po-Tsarng Huang, Wen-Tar Wu, Yu-Shuan Shiau, Kuo-Long Lou, Jean-San Chia
Publikováno v:
Journal of molecular modeling. 9(3)
Glucosyltransferases (GtfB/C/D) in Streptococcus mutans are responsible for synthesizing water-insoluble and water-soluble glucans from sucrose and play very crucial roles in the formation of dental plaque. A monoclonal antibody against a 19-mer pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0189636acae241f262c2bd1651f70754
https://pubmed.ncbi.nlm.nih.gov/12750965
https://pubmed.ncbi.nlm.nih.gov/12750965