Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yu-Shu Ge"'
Publikováno v:
Acta crystallographica. Section D, Structural biology. 77(Pt 12)
As one of the most abundant bacteria in the human oral cavity, Fusobacterium nucleatum is closely involved in various oral diseases and is also a risk factor for other diseases. The peptidases of F. nucleatum can digest exogenous peptides into amino
Publikováno v:
European Journal of Medicinal Chemistry. 143:1090-1102
Considering the vital role of cellular redox state, more and more researches focus on the design of drugs targeting thioredoxin reductase (TrxR), an important enzyme in maintaining the balance of cellular redox. Here two organic arsenicals, 2-(((4-(1
Publikováno v:
The Journal of Membrane Biology. 248:727-740
Quantum dots (QDs) are increasingly applied in sensing, drug delivery, biomedical imaging, electronics industries, etc. Consequently, it is urgently required to examine their potential threat to humans and the environment. In the present work, the to
Publikováno v:
The journal of physical chemistry. B. 121(6)
The amino naphthalene 2-cyanoacrylate (ANCA) probe is a kind of fluorescent amyloid binding probe that can report different fluorescence emissions when bound to various amyloid deposits in tissue, while their interactions with amyloid fibrils remain
Publikováno v:
ChemMedChem. 12(6)
Cdc25 phosphatase was studied as an attractive target for cancer therapy. Multiple pharmacophore models with the unique core features of classic quinone inhibitors and those of novel inhibitors were used to discover a novel lead inhibitor. A total of
Publikováno v:
Journal of the American Chemical Society. 136:56-59
We have first demonstrated the distinctive effects of three newly reported epigenetic modifications, including 5hmC, 5fC, and 5caC, on B-Z transition of CpG dinucleotide DNAs. We have performed detailed assays and compared their effects. We further s
Autor:
Xiang Zhou, Qianqian Zhai, Xiaocheng Weng, Yi Liu, Yu-Shu Ge, Tingting Hong, Lin Liu, Peng Hu
Publikováno v:
Inorganica Chimica Acta. 394:385-390
Ruthenium complexes are well known for their high affinity and reactivity with DNA. There are so many reports about the interactions of ruthenium complexes and duplex DNA. However, their effects on other DNA structures are poorly studied. In this pap
Publikováno v:
Luminescence. 28:865-872
5-Fluorouracil (5-FU) has been widely used as a chemotherapy agent in the treatment of many types of solid tumors. Investigation of its antimetabolites led to the development of an entire class of fluorinated pyrimidines. However, the toxicity profil
Autor:
Yu-Shu Ge, Lu Lai, Dong-Wei Li, Zi-Qiang Xu, Ping Mei, Chen Lin, Ye-Zhong Zhang, Xiao-Le Han, Feng-Lei Jiang, Fang-Fang Tian, Yi Liu
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 97:366-376
This paper investigates the interactions between human serum albumin (HSA) and CdTe quantum dots (QDs) with nearly identical hydrodynamic size, but capped with four different ligands (MPA, NAC, and GSH are negatively charged; CA is positively charged
Autor:
Fang-Fang Tian, Feng-Lei Jiang, Yu-Shu Ge, Dong-Wei Li, Xiao-Le Han, Chen Lin, Jia Wang, Lu Lai, Qiuliyang Yu, Yi Liu
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 109:1-11
Chlorpyrifos (CPF) is a widely used organophosphate insecticide which could bind with human serum albumin (HSA) and bovine serum albumin (BSA). The binding behavior was studied employing fluorescence, three-dimensional fluorescence, Circular dichrois