Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Yu-Shi Tian"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Monoamine oxidase B (MAO-B) inhibitors are used to control Parkinson’s disease (PD). Selegiline, rasagiline, and safinamide are widely used as MAO-B inhibitors worldwide. Although these drugs inhibit MAO-B, there are pharmacological and ch
Externí odkaz:
https://doaj.org/article/5739f0e758bb48f68a0afef196f729f6
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-22 (2023)
Abstract Background Microarray data have been widely utilized for cancer classification. The main characteristic of microarray data is “large p and small n” in that data contain a small number of subjects but a large number of genes. It may affec
Externí odkaz:
https://doaj.org/article/8044e78e779141c182e931fa11576716
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The severe side effects of some drugs can threaten the lives of patients and financially jeopardize pharmaceutical companies. Computational methods utilizing chemical, biological, and phenotypic features have been used to address this proble
Externí odkaz:
https://doaj.org/article/99ee22706af2419b8097c26b3c666f1d
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Even though R is one of the most commonly used statistical computing environments, it lacks a graphical user interface (GUI) that appeals to students, researchers, lecturers, and practitioners in medicine and pharmacy for conducti
Externí odkaz:
https://doaj.org/article/5180b32dffce43088b76f892c9c26ce7
Autor:
Asuka Hatabu, Xinhua Mao, Yi Zhou, Norihito Kawashita, Zheng Wen, Mikiko Ueda, Tatsuya Takagi, Yu-Shi Tian
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244350 (2020)
The coronavirus disease (COVID-19) pandemic has greatly altered peoples' daily lives, and it continues spreading as a crucial concern globally. Knowledge, attitudes, and practices (KAP) toward COVID-19 are related to individuals' adherence to governm
Externí odkaz:
https://doaj.org/article/30a4c2f2744d47eda6a1d15c327c70dd
Publikováno v:
Journal of Cheminformatics, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Molecular descriptors are widely employed to present molecular characteristics in cheminformatics. Various molecular-descriptor-calculation software programs have been developed. However, users of those programs must contend with several iss
Externí odkaz:
https://doaj.org/article/42b97054632d43efaad83802d36a441f
Publikováno v:
International Journal of Clinical Pharmacy. 44:587-598
Clinical differences between degludec U100 (Deg-100) and glargine U300 (Gla-300) in type 1 diabetes (T1D) were unknown.To indirectly compare the safety, efficacy, and cost-effectiveness between Deg-100 and Gla-300 in T1D adults via systematic review.
In this PRISMA-compliant systematic review and meta-analysis, we aimed to assess the efficacy of golimumab (GOL) against non-infectious uveitis (NIU). We included eight articles in the meta-analysis. The primary outcome was inflammation remission. Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4224166b8efd7ee1ec2307188006d06c
Autor:
Norihito Kawashita, Kazuki Watanabe, Yusuke Kawashima, Yu-Shi Tian, Teruki Honma, Kaori Fukuzawa, Chiduru Watanabe, Tatsuya Takagi
Publikováno v:
The Journal of Physical Chemistry Letters
The spike glycoprotein (S-protein) mediates SARS-CoV-2 entry via intermolecular interaction with human angiotensin-converting enzyme 2. The receptor binding domain (RBD) of the S-protein has been considered critical for this interaction and acts as t
Publikováno v:
Chem-Bio Informatics Journal. 21:1-10