Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Yu-Qiu Zhang"'
Autor:
Jia-Rui Zhang, Shi-Yu Shen, Meng-Ying Zhai, Zu-Qi Shen, Wei Li, Ling-Feng Liang, Shu-Yuan Yin, Qiu-Qin Han, Bing Li, Yu-Qiu Zhang, Jin Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Extracellular ATP (eATP) signaling through the P2X7 receptor pathway is widely believed to trigger NLRP3 inflammasome assembly in microglia, potentially contributing to depression. However, the cellular stress responses of microglia to both
Externí odkaz:
https://doaj.org/article/82568303fa194a57ad4b0a544635e762
Autor:
Shi-Yu Shen, Rui Yu, Wei Li, Ling-Feng Liang, Qiu-Qin Han, Hui-Jie Huang, Bing Li, Shi-Fen Xu, Gen-Cheng Wu, Yu-Qiu Zhang, Jin Yu
Publikováno v:
Neurobiology of Disease, Vol 169, Iss , Pp 105743- (2022)
Depression is one of the most prevalent mental illnesses in the world today, and the onset of depression is usually accompanied by neuroinflammation and impaired adult neurogenesis. As a new potential member of the endocannabinoid (eCB) system, G pro
Externí odkaz:
https://doaj.org/article/b838943548264e199b1cd44f08e01588
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Ca2+/calmodulin-stimulated group I adenylyl cyclase (AC) isoforms AC1 and AC8 have been involved in nociceptive processing and morphine responses. However, whether AC3, another member of group I ACs, is involved in nociceptive transmission and regula
Externí odkaz:
https://doaj.org/article/6984fb3776c743ff8e23408a2ad519aa
Autor:
Hao-Yuan Li, Jing Wang, Ling-Feng Liang, Shi-Yu Shen, Wei Li, Xiao-Rong Chen, Bing Li, Yu-Qiu Zhang, Jin Yu
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1886 (2022)
An estimated 20% of women experience depression at some point during menopause. Hormone replacement therapy (HRT), as the main therapy for depression and other menopausal syndromes, comes with a few undesirable side effects and a potential increase i
Externí odkaz:
https://doaj.org/article/49da4fe3cd304c2b8f38138b64bf642e
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
Recently programmed death-ligand 1 (PD-L1) receptor PD-1 was found in dorsal root ganglion (DRG) neurons, and PD-L1 activates PD-1 to inhibit inflammatory and neuropathic pain by modulating neuronal excitability. However, the downstream signaling of
Externí odkaz:
https://doaj.org/article/003b32980f8645629b203457462617c5
Autor:
Hai-Yan Sheng, Su-Su Lv, Ya-Qi Cai, Wu Shi, Wei Lin, Ting-Ting Liu, Ning Lv, Hong Cao, Ling Zhang, Yu-Qiu Zhang
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Depression and anxiety are frequently observed in patients suffering from neuropathic pain. The underlying mechanisms remained unclear. The ventrolateral orbital cortex (VLO) has attracted considerable interest in its role in antidepressive effect in
Externí odkaz:
https://doaj.org/article/e2a99edc007a455b84a5de5770fcd210
Autor:
Hao Luo, Hui-Zhu Liu, Wen-Wen Zhang, Megumi Matsuda, Ning Lv, Gang Chen, Zhen-Zhong Xu, Yu-Qiu Zhang
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2384-2397.e5 (2019)
Summary: The proinflammatory cytokine interleukin-17 (IL-17) is implicated in pain regulation. However, the synaptic mechanisms by which IL-17 regulates pain transmission are unknown. Here, we report that glia-produced IL-17 suppresses inhibitory syn
Externí odkaz:
https://doaj.org/article/f297f1605049415dad3dca90753f9ad7
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118842 (2015)
The long-term potentiation (LTP) of spinal C-fiber-evoked field potentials is considered as a fundamental mechanism of central sensitization in the spinal cord. Accumulating evidence has showed the contribution of spinal microglia to spinal LTP and p
Externí odkaz:
https://doaj.org/article/9e181c614e394cc98cda879626ffe4f9
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94312 (2014)
Decline in the ovarian hormones with menopause may influence somatosensory, cognitive, and affective processing. The present study investigated whether hormonal depletion alters the nociceptive, depressive-like and learning behaviors in experimental
Externí odkaz:
https://doaj.org/article/17c27f570f1f4d179f35adb0e6b2fbe5
Autor:
Liu Yang, Li-Jun Shi, Shi-Yu Shen, Jing-Yan Yang, Su-Su Lv, Zhe-Chen Wang, Qian Huang, Wen-Dong Xu, Jin Yu, Yu-Qiu Zhang
Publikováno v:
Psychological Science. 34:616-632
Social adversity not only causes severe psychological diseases but also may improve people’s ability to learn and grow. However, the beneficial effects of social adversity are often ignored. In this study, we investigated whether and how social adv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b07ef9e85e95678f5ad26abc9747aa5
https://doi.org/10.1177/09567976231160098
https://doi.org/10.1177/09567976231160098