Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Yu-Liang Ran"'
Anti-ENO1 antibody combined with metformin against tumor resistance: a novel antibody-based platform
Publikováno v:
PeerJ, Vol 12, p e16817 (2024)
Background Antibody-based platforms (i.e., ADC) have emerged as one of the most encouraging tools for the cancer resistance caused by cancer stem cells (CSCs) enrichment. Our study might provide a promising therapeutic direction against drug resistan
Externí odkaz:
https://doaj.org/article/2ccf73ec7e4a4014aa6c3c72707ade67
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Identification of promising targeted antigens that exhibited cancer-specific expression is a crucial step in the development of novel antibody-targeted therapies. We here aimed to investigate the anti-tumor activity of a novel mon
Externí odkaz:
https://doaj.org/article/c7170e3734904acb9ae5d7abb68d3078
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 4510-4520 (2023)
Abstract Background Cancer stem cells (CSCs) are responsible for drug resistance, cancer relapse, and metastasis. Here, we report the first analysis of Palladin expression and its impacts on stem cell‐like properties in lung cancer. Methods Tissue
Externí odkaz:
https://doaj.org/article/8ecc521751d14e81b0a094f834ab8fc2
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract The fatality rate of non-small cell lung cancer (NSCLC) has been high due to the existence of cancer stem cells (CSCs). Non-muscle myosin heavy chain 9 (MYH9) can promote the progression of various tumors, but its effect on the stem cell-lik
Externí odkaz:
https://doaj.org/article/f189122911c94f8dae0738e25e9c8a2d
Autor:
Xiong Shu, Kai-Yue Cao, Hui-Qi Liu, Long Yu, Li-Xin Sun, Zhi-Hua Yang, Cheng-Ai Wu, Yu-Liang Ran
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Tumor-associated antigens (TAAs) can be targeted in cancer therapy. We previously identified a monoclonal antibody (mAb) 12C7, which presented anti-tumor activity in lung cancer stem cells (LCSCs). Here, we aimed to identify the t
Externí odkaz:
https://doaj.org/article/9996d4d6fee94d6aa21bc9ea48b3312c
Publikováno v:
PeerJ, Vol 9, p e12115 (2021)
Osteosarcoma (OS) is a primary malignant tumor of bone occurring in young adults. OS stem cells (OSCs) play an important role in the occurrence, growth, metastasis, drug resistance and recurrence of OS. CD133 is an integral membrane glycoprotein, whi
Externí odkaz:
https://doaj.org/article/95b663f1eca94d3495ae45b078375ee8
Autor:
Xiong Shu, Pan-Pan Zhan, Li-Xin Sun, Long Yu, Jun Liu, Li-Chao Sun, Zhi-Hua Yang, Yu-Liang Ran, Yue-Min Sun
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
BackgroundFocusing on antiangiogenesis may provide promising choices for treatment of gastric cancer (GC). This study aimed to investigate the mechanistic role of BCAT1 in the pathogenesis of GC, particularly in angiogenesis.MethodsBioinformatics and
Externí odkaz:
https://doaj.org/article/2cb5f8821fcf44bbb669d046cd832e9c
Publikováno v:
Precision Radiation Oncology, Vol 3, Iss 2, Pp 44-51 (2019)
Abstract Objective The incidence and mortality rate of lung cancer ranks first among all malignant tumors. Lymph node metastasis is the most common mode of metastasis in lung cancer, and it is also an important indicator for treatment strategies and
Externí odkaz:
https://doaj.org/article/1fbd1a0f1a8c49de8cf6cc7f8c564970
Publikováno v:
Cancer medicineREFERENCES.
Cancer stem cells (CSCs) are responsible for drug resistance, cancer relapse, and metastasis. Here, we report the first analysis of Palladin expression and its impacts on stem cell-like properties in lung cancer.Tissue microarrays were used to invest
Autor:
Zhi-jun, Yang, Guang, Yang, Yan-ming, Jiang, Yu-liang, Ran, Zhi-hua, Yang, Wei, Zhang, Jie-qing, Zhang, Zhong-mian, Pan, Li, Li
Publikováno v:
Zhonghua fu chan ke za zhi. 46(2)
To evaluate the clinical value of autoantibody spectrum against ovarian cancer associated antigens combine CA(125) in detecting and monitoring ovarian cancer.Circulating IgG, IgM autoantibodies against ovarian cancer associated antigens which include