Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Yu-Jui Ho"'
Autor:
Takahiro Shibayama, Akimasa Hayashi, Masao Toki, Keiichiro Kitahama, Yu-Jui Ho, Kenichiro Kato, Takahiro Yamada, Sho Kawamoto, Komei Kambayashi, Kazushige Ochiai, Koichi Gondo, Naohiro Okano, Jerry P. Melchor, Christine A. Iacobuzio-Donahue, Yoshihiro Sakamoto, Tadakazu Hisamatsu, Junji Shibahara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Although sequence-based studies show that basal-like features lead to worse prognosis and chemotherapy-resistance compared to the classical subtype in advanced pancreatic ductal adenocarcinoma (PDAC), a surrogate biomarker distinguishing bet
Externí odkaz:
https://doaj.org/article/62dc4ee5968d4df19cb11b90bf76aca0
Autor:
Changyu Zhu, Yadira M Soto-Feliciano, John P Morris, Chun-Hao Huang, Richard P Koche, Yu-jui Ho, Ana Banito, Chun-Wei Chen, Aditya Shroff, Sha Tian, Geulah Livshits, Chi-Chao Chen, Myles Fennell, Scott A Armstrong, C David Allis, Darjus F Tschaharganeh, Scott W Lowe
Publikováno v:
eLife, Vol 12 (2023)
Mutations in genes encoding components of chromatin modifying and remodeling complexes are among the most frequently observed somatic events in human cancers. For example, missense and nonsense mutations targeting the mixed lineage leukemia family me
Externí odkaz:
https://doaj.org/article/00891c2adbc24612b3cca84dd953d236
Autor:
Arnab Ghosh, Judith Michels, Riccardo Mezzadra, Divya Venkatesh, Lauren Dong, Ricardo Gomez, Fadi Samaan, Yu-Jui Ho, Luis Felipe Campesato, Levi Mangarin, John Fak, Nathan Suek, Aliya Holland, Cailian Liu, Mohsen Abu-Akeel, Yonina Bykov, Hong Zhong, Kelly Fitzgerald, Sadna Budhu, Andrew Chow, Roberta Zappasodi, Katherine S. Panageas, Olivier de Henau, Marcus Ruscetti, Scott W. Lowe, Taha Merghoub, Jedd D. Wolchok
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 18 (2022)
In addition to playing a major role in tumor cell biology, p53 generates a microenvironment that promotes antitumor immune surveillance via tumor-associated macrophages. We examined whether increasing p53 signaling in the tumor microenvironment influ
Externí odkaz:
https://doaj.org/article/4dd0c33291a24e69965b3018d2f98727
103
Background: Inhibiting the responses to inappropriate stimuli or behaviors is an essential cognitive ability for humans. Go/No-Go tasks have been widely used to investigate response inhibition processes. Pre-attentive Sensory gating, or cort
Background: Inhibiting the responses to inappropriate stimuli or behaviors is an essential cognitive ability for humans. Go/No-Go tasks have been widely used to investigate response inhibition processes. Pre-attentive Sensory gating, or cort
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/28184509510013790543
101
It has been more than forty years since the raising of ecotourism concept. Improving tourists education, environmental protection and preservation zone sustainable development have been the ultimate objective for many ecotourism locations. T
It has been more than forty years since the raising of ecotourism concept. Improving tourists education, environmental protection and preservation zone sustainable development have been the ultimate objective for many ecotourism locations. T
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/60994123802611355991
Autor:
Jing Hu, Francisco J. Sánchez-Rivera, Zhenghan Wang, Gabriela N. Johnson, Yu-jui Ho, Karuna Ganesh, Shigeaki Umeda, Siting Gan, Adriana M. Mujal, Rebecca B. Delconte, Jessica P. Hampton, Huiyong Zhao, Sanjay Kottapalli, Elisa de Stanchina, Christine A. Iacobuzio-Donahue, Dana Pe’er, Scott W. Lowe, Joseph C. Sun, Joan Massagué
Publikováno v:
Nature. 616:806-813
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502025a43230aef2521cdf7689f1290c
https://doi.org/10.1038/s41586-023-05880-5
https://doi.org/10.1038/s41586-023-05880-5
Autor:
Yadira M. Soto-Feliciano, Francisco J. Sánchez-Rivera, Florian Perner, Douglas W. Barrows, Edward R. Kastenhuber, Yu-Jui Ho, Thomas Carroll, Yijun Xiong, Disha Anand, Alexey A. Soshnev, Leah Gates, Mary Clare Beytagh, David Cheon, Shengqing Gu, X. Shirley Liu, Andrei V. Krivtsov, Maximiliano Meneses, Elisa de Stanchina, Richard M. Stone, Scott A. Armstrong, Scott W. Lowe, C. David Allis
Publikováno v:
Cancer Discovery. 13:146-169
Menin interacts with oncogenic MLL1-fusion proteins, and small molecules that disrupt these associations are in clinical trials for leukemia treatment. By integrating chromatin-focused and genome-wide CRISPR screens with genetic, pharmacologic, and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5aebdeae24ecc0935e8aeab3707bed
https://doi.org/10.1158/2159-8290.cd-22-0416
https://doi.org/10.1158/2159-8290.cd-22-0416
Autor:
Timour Baslan, John P. Morris, Zhen Zhao, Jose Reyes, Yu-Jui Ho, Kaloyan M. Tsanov, Jonathan Bermeo, Sha Tian, Sean Zhang, Gokce Askan, Aslihan Yavas, Nicolas Lecomte, Amanda Erakky, Anna M. Varghese, Amy Zhang, Jude Kendall, Elena Ghiban, Lubomir Chorbadjiev, Jie Wu, Nevenka Dimitrova, Kalyani Chadalavada, Gouri J. Nanjangud, Chaitanya Bandlamudi, Yixiao Gong, Mark T. A. Donoghue, Nicholas D. Socci, Alex Krasnitz, Faiyaz Notta, Steve D. Leach, Christine A. Iacobuzio-Donahue, Scott W. Lowe
Publikováno v:
Nature. 608:795-802
Although p53 inactivation promotes genomic instability1 and presents a route to malignancy for more than half of all human cancers2,3, the patterns through which heterogenous TP53 (encoding human p53) mutant genomes emerge and influence tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d92e4faced4f3453550dbf42fecb004
https://doi.org/10.1038/s41586-022-05082-5
https://doi.org/10.1038/s41586-022-05082-5
Autor:
Walid K. Chatila, Jin K. Kim, Henry Walch, Michael R. Marco, Chin-Tung Chen, Fan Wu, Dana M. Omer, Danny N. Khalil, Karuna Ganesh, Xuan Qu, Anisha Luthra, Seo-Hyun Choi, Yu-Jui Ho, Ritika Kundra, Katharine I. Groves, Oliver S. Chow, Andrea Cercek, Martin R. Weiser, Maria Widmar, Iris H. Wei, Emmanouil P. Pappou, Garrett M. Nash, Philip B. Paty, Qian Shi, Efsevia Vakiani, S. Duygu Selcuklu, Mark T. A. Donoghue, David B. Solit, Michael F. Berger, Jinru Shia, Raphael Pelossof, Paul B. Romesser, Rona Yaeger, J. Joshua Smith, Nikolaus Schultz, Francisco Sanchez-Vega, Julio Garcia-Aguilar
Publikováno v:
Nat Med
The incidence of rectal cancer is increasing in patients younger than 50 years. Locally advanced rectal cancer is still treated with neoadjuvant radiation, chemotherapy and surgery, but recent evidence suggests that patients with a complete response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7587d7b225d8c923fe2f9f0ee5570cca
https://doi.org/10.1038/s41591-022-01930-z
https://doi.org/10.1038/s41591-022-01930-z
Autor:
Cassandra Burdziak, Direna Alonso-Curbelo, Thomas Walle, José Reyes, Francisco M. Barriga, Doron Haviv, Yubin Xie, Zhen Zhao, Chujun Julia Zhao, Hsuan-An Chen, Ojasvi Chaudhary, Ignas Masilionis, Zi-Ning Choo, Vianne Gao, Wei Luan, Alexandra Wuest, Yu-Jui Ho, Yuhong Wei, Daniela F. Quail, Richard Koche, Linas Mazutis, Ronan Chaligné, Tal Nawy, Scott W. Lowe, Dana Pe’er
Publikováno v:
Science. 380
The response to tumor-initiating inflammatory and genetic insults can vary among morphologically indistinguishable cells, suggesting as yet uncharacterized roles for epigenetic plasticity during early neoplasia. To investigate the origins and impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c1d23407cd338152d43ece94589b91a
https://doi.org/10.1126/science.add5327
https://doi.org/10.1126/science.add5327