Cis-3-O-p-hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells

Autor: Chi Ren Liao, Ching Ying Wang, Yuan-Shiun Chang, Chun Hung Hua, Mann-Jen Hour, Cheng Wen Lin, Su Hua Huang, Chen Sheng Lin, Yu Jen Jou, Lei Wan

Publikováno v: Biomolecules & Therapeutics

Cis-3-O-p-hydroxycinnamoyl ursolic acid (HCUA), a triterpenoid compound, was purified from Elaeagnus oldhamii Maxim. This traditional medicinal plant has been used for treating rheumatoid arthritis and lung disorders as well as for its anti-inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455efc70cb87e9dc253d88a3afa14b83
http://europepmc.org/articles/PMC6319548

S100A8 as potential salivary biomarker of oral squamous cell carcinoma using nanoLC–MS/MS

Autor: Chun Hung Hua, Yu Jen Jou, Chia-Der Lin, Chih Ho Lai, Su Hua Huang, Jung-Yie Kao, Ming Hsui Tsai, Cheng Wen Lin

Publikováno v: Clinica Chimica Acta. 436:121-129

Background Oral squamous cell carcinoma (OSCC) shows low 5-year survival; early treatment greatly reduces mortality and morbidity. Saliva is a non-invasive sample, with good potential to discover biomarkers for early detection. Methods NanoLC–MS/MS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94fb7e5240f90c13d7d040e6f1113e8
https://doi.org/10.1016/j.cca.2014.05.009

SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6

Autor: Yu Jen Jou, Lei Wan, Cheng Wen Lin, Szu Hao Kung, Ying Ju Lin, Ching Ying Wang, Shih Wen Li, Li Hsin Hsiao, Su Hua Huang

Publikováno v: International journal of molecular sciences, 17(5):678
International Journal of Molecular Sciences, Vol 17, Iss 5, p 678 (2016)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 5; Pages: 678

Severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLPro) reportedly inhibits the production of type I interferons (IFNs) and pro-inflammatory cytokines in Toll-like receptor 3 (TLR3) and retinoic acid-inducible gene 1 (RI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a99efde6b5362a62fd34974972cae9
https://repository.publisso.de/resource/frl:6420605

Study on human salivary biomarkers of oral cancer and molecular mechanisms of anti-oral cancer agents using proteomic technology

Autor: Yu-Jen Jou, 周于楨

103
Oral squamous cell carcinoma (OSCC) is a worldwide malignant that has emerging as a public health problem in Taiwan. Saliva is a non-invasive sample with good potential to investigate biomarkers for early diagnosis of oral cancer. In our pro

Externí odkaz: http://ndltd.ncl.edu.tw/handle/93599009990105050285

Eupafolin and Ethyl Acetate Fraction of Kalanchoe gracilis Stem Extract Show Potent Antiviral Activities against Enterovirus 71 and Coxsackievirus A16

Autor: Yu Jen Jou, Szu Hao Kung, Yongjun Zhang, Ching Ying Wang, Zhen Rung Lai, Shun Chueh Huang, Yu-Ling Ho, Cheng Wen Lin, Yuan-Shiun Chang

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2013 (2013)

Enterovirus 71 (EV71) and coxsackievirus A16 (CoxA16) are main pathogens of hand-foot-and-mouth disease, occasionally causing aseptic meningitis and encephalitis in tropical and subtropical regions.Kalanchoe gracilis,Da-Huan-Hun, is a Chinese folk me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed60ba00e64b7beab8384123d5a93d0